KEGG   ORTHOLOGY: K04175Help
Entry
K04175                      KO                                     

Name
CXCR1, IL8RA, CD181
Definition
C-X-C chemokine receptor type 1
Pathway
Cytokine-cytokine receptor interaction
Chemokine signaling pathway
Phospholipase D signaling pathway
Endocytosis
Epithelial cell signaling in Helicobacter pylori infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04072 Phospholipase D signaling pathway
    K04175  CXCR1, IL8RA, CD181; C-X-C chemokine receptor type 1
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K04175  CXCR1, IL8RA, CD181; C-X-C chemokine receptor type 1
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    K04175  CXCR1, IL8RA, CD181; C-X-C chemokine receptor type 1
 Organismal Systems
  Immune system
   04062 Chemokine signaling pathway
    K04175  CXCR1, IL8RA, CD181; C-X-C chemokine receptor type 1
 Human Diseases
  Infectious diseases
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K04175  CXCR1, IL8RA, CD181; C-X-C chemokine receptor type 1
G protein-coupled receptors [BR:ko04030]
 Class A. Rhodopsin family
  Chemokine
   CXC Chemokine
    K04175  CXCR1, IL8RA, CD181; C-X-C chemokine receptor type 1
Cytokine receptors [BR:ko04050]
 Chemokine receptors
  CXC Chemokine
   K04175  CXCR1, IL8RA, CD181; C-X-C chemokine receptor type 1
CD molecules [BR:ko04090]
 Proteins
  K04175  CD181, CXCR1; chemokine (C-X-C motif) receptor 1
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
3577(CXCR1)
PTR: 
470645(CXCR1)
PPS: 
100979257(CXCR1)
GGO: 
101152473(CXCR1)
PON: 
100461947(CXCR1)
NLE: 
MCC: 
692074(CXCR1)
MCF: 
102140902(CXCR1)
CSAB: 
103217856(CXCR1)
RRO: 
104660012(CXCR1)
CJC: 
100385951(CXCR1)
SBQ: 
101037560(CXCR1)
MMU: 
227288(Cxcr1)
RNO: 
54258(Cxcr1)
CGE: 
NGI: 
103727810(Cxcr1)
HGL: 
101712235(Cxcr1)
OCU: 
100328622(CXCR1)
TUP: 
102484375(CXCR1)
BTA: 
281863(CXCR1)
LAV: 
100653621(CXCR1)
TNG: 
SASA: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1840701
  Authors
Holmes WE, Lee J, Kuang WJ, Rice GC, Wood WI
  Title
Structure and functional expression of a human interleukin-8 receptor.
  Journal
Science 253:1278-80 (1991)
DOI:10.1126/science.1840701
  Sequence
[hsa:3577]
Reference
  Authors
Horuk R.
  Title
Chemokine receptors.
  Journal
Cytokine Growth Factor Rev 12:313-35 (2001)
DOI:10.1016/S1359-6101(01)00014-4
Reference
  Authors
Fan X, Patera AC, Pong-Kennedy A, Deno G, Gonsiorek W, Manfra DJ, Vassileva G, Zeng M, Jackson C, Sullivan L, Sharif-Rodriguez W, Opdenakker G, Van Damme J, Hedrick JA, Lundell D, Lira SA, Hipkin RW
  Title
Murine CXCR1 is a functional receptor for GCP-2/CXCL6 and interleukin-8/CXCL8.
  Journal
J Biol Chem 282:11658-66 (2007)
DOI:10.1074/jbc.M607705200
  Sequence
[mmu:227288]

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