KEGG ORTHOLOGY: K04189

ORTHOLOGY: K04189

Entry

K04189 KO

Name

CXCR4

Definition

C-X-C chemokine receptor type 4

Pathway

ko04060	Cytokine-cytokine receptor interaction
ko04062	Chemokine signaling pathway
ko04144	Endocytosis
ko04360	Axon guidance
ko04670	Leukocyte transendothelial migration
ko04672	Intestinal immune network for IgA production

Disease

H00097

Chemokine receptor defect

Brite

KEGG Orthology (KO) [BR:ko00001]
Environmental Information Processing
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K04189  CXCR4; C-X-C chemokine receptor type 4
Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    K04189  CXCR4; C-X-C chemokine receptor type 4
Organismal Systems
  Immune system
   04670 Leukocyte transendothelial migration
    K04189  CXCR4; C-X-C chemokine receptor type 4
   04672 Intestinal immune network for IgA production
    K04189  CXCR4; C-X-C chemokine receptor type 4
   04062 Chemokine signaling pathway
    K04189  CXCR4; C-X-C chemokine receptor type 4
  Development
   04360 Axon guidance
    K04189  CXCR4; C-X-C chemokine receptor type 4
G protein-coupled receptors [BR:ko04030]
Class A. Rhodopsin family
  Chemokine
   CXC Chemokine
    K04189  CXCR4; C-X-C chemokine receptor type 4
Cytokine receptors [BR:ko04050]
Chemokine receptors
  CXC Chemokine
   K04189  CXCR4; C-X-C chemokine receptor type 4
Cellular antigens [BR:ko04090]
Proteins
  K04189  CD184, CXCR4; chemokine (C-X-C motif) receptor 4

Other DBs

GO:

0016494

Genes

HSA:	7852(CXCR4)
PTR:	450130(CXCR4)
PPS:	100968161(CXCR4)
GGO:	101137662(CXCR4)
PON:	100451032(CXCR4)
MCC:	707329(CXCR4)
MMU:	12767(Cxcr4)
RNO:	60628(Cxcr4)
CFA:	483900(CXCR4)
AML:	100468194
FCA:	493676(CXCR4)
BTA:	281736(CXCR4)
SSC:	396659(CXCR4)
ECB:	100050974
MDO:	100016627
SHR:	100918513
OAA:	100079713
GGA:	395324(CXCR4)
MGP:	100541154
TGU:	100229955(CXCR4)
ACS:	100567304
XLA:	100192360(cxcr4-a) 380373(cxcr4-b)
XTR:	100038176(cxcr4)
DRE:	114447(cxcr4b) 140747(cxcr4a)
TRU:	101066475
OLA:	100049444(cxcr4)

» show all

Reference

PMID:11544102

Authors

Horuk R.

Title

Chemokine receptors.

Journal

Cytokine Growth Factor Rev 12:313-35 (2001)

All links

Ontology (9)   
   KEGG BRITE (8)   
   GO (1)   
Pathway (12)   
   KEGG PATHWAY (12)   
Disease (1)   
   KEGG DISEASE (1)   
Drug (1)   
   KEGG DRUG (1)   
Chemical substance (1)   
   KEGG COMPOUND (1)   
Gene (37)   
   KEGG GENES (28)   
   KEGG DGENES (1)   
   KEGG EGENES (8)   
Protein sequence (22)   
   UniProt (22)   
Literature (1)   
   PubMed (1)   
All databases (84)   

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