KEGG   ORTHOLOGY: K04348Help
Entry
K04348                      KO                                     

Name
PPP3C, CNA
Definition
serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Pathway
MAPK signaling pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
Oocyte meiosis
Apoptosis
Wnt signaling pathway
Axon guidance
VEGF signaling pathway
Osteoclast differentiation
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Long-term potentiation
Glutamatergic synapse
Dopaminergic synapse
Oxytocin signaling pathway
Alzheimer's disease
Amyotrophic lateral sclerosis (ALS)
Amphetamine addiction
Tuberculosis
HTLV-I infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
   04310 Wnt signaling pathway
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
   04370 VEGF signaling pathway
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
   04020 Calcium signaling pathway
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
   04022 cGMP - PKG signaling pathway
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
 Cellular Processes
  Cell growth and death
   04114 Oocyte meiosis
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
   04210 Apoptosis
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
   04660 T cell receptor signaling pathway
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
   04662 B cell receptor signaling pathway
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
  Endocrine system
   04921 Oxytocin signaling pathway
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
  Nervous system
   04724 Glutamatergic synapse
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
   04728 Dopaminergic synapse
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
   04720 Long-term potentiation
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
  Development
   04360 Axon guidance
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
   04380 Osteoclast differentiation
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
 Human Diseases
  Neurodegenerative diseases
   05010 Alzheimer's disease
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
   05014 Amyotrophic lateral sclerosis (ALS)
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
  Substance dependence
   05031 Amphetamine addiction
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
  Infectious diseases
   05152 Tuberculosis
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
   05166 HTLV-I infection
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
Protein phosphatases and associated proteins [BR:ko01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
BRITE hierarchy
Other DBs
COG: 
GO: 
Genes
HSA: 
5530(PPP3CA) 5532(PPP3CB) 5533(PPP3CC)
PTR: 
450898(PPP3CB) 461403(PPP3CA) 742406(PPP3CC)
PPS: 
100968593(PPP3CB) 100976831(PPP3CC) 100976987(PPP3CA)
GGO: 
101132713(PPP3CB) 101144930(PPP3CA) 101146305(PPP3CC)
PON: 
100174530(PPP3CA) 100436675(PPP3CB) 100455542(PPP3CC)
NLE: 
100583664(PPP3CA) 100597098 100598029(PPP3CC) 100607264(PPP3CB)
MCC: 
706955(PPP3CB) 708233(PPP3CC) 709773(PPP3CA)
MCF: 
CJC: 
100386369(PPP3CA) 100386452(PPP3CC) 100387059(PPP3CB)
MMU: 
19055(Ppp3ca) 19056(Ppp3cb) 19057(Ppp3cc)
RNO: 
171378(Ppp3cc) 24674(Ppp3ca) 24675(Ppp3cb)
CGE: 
100751412(Ppp3cc) 100752571 100764987(Ppp3cb)
NGI: 
103728037(Ppp3ca) 103736944(Ppp3cb) 103747869(Ppp3cc)
HGL: 
101698959(Ppp3ca) 101708178(Ppp3cb) 101719947(Ppp3cc)
OCU: 
100009423(PPP3CA) 100009487(PPP3CB) 100356245(PPP3CC)
TUP: 
102478627(PPP3CB) 102478870 102480885(PPP3CC)
CFA: 
403486(PPP3CA) 479248(PPP3CB) 609027(PPP3CC)
AML: 
UMR: 
103667825(PPP3CB) 103673318(PPP3CC) 103677943(PPP3CA)
FCA: 
101086926(PPP3CB) 101093097(PPP3CC) 101097144(PPP3CA)
PTG: 
102949359(PPP3CC) 102952632(PPP3CA) 102963447(PPP3CB)
BTA: 
286852(PPP3CA) 533527(PPP3CC) 790867(PPP3CB)
BOM: 
102266749(PPP3CA) 102275863(PPP3CB) 102286752(PPP3CC)
PHD: 
102316775(PPP3CC) 102317711(PPP3CA) 102329404(PPP3CB)
CHX: 
102176770(PPP3CA) 102179767(PPP3CC) 102184033(PPP3CB)
OAS: 
101108104(PPP3CB) 101115429(PPP3CC) 101122602(PPP3CA)
SSC: 
100158082(PPP3CC) 396603(PPP3CB) 397241(PPP3CA)
CFR: 
102505131(PPP3CA) 102513924(PPP3CB) 102515660(PPP3CC)
BACU: 
102997475(PPP3CA) 103008480(PPP3CC) 103009446(PPP3CB)
LVE: 
103070526(PPP3CC) 103088182(PPP3CB) 103090427(PPP3CA)
ECB: 
100057357(PPP3CC) 100067434(PPP3CA) 100072862(PPP3CB)
MYB: 
102245752 102251300(PPP3CB) 102264111(PPP3CC)
MYD: 
102753757(PPP3CC) 102754623(PPP3CB) 102755500(PPP3CA)
PALE: 
102880029(PPP3CA) 102883156(PPP3CB) 102898473(PPP3CC)
MDO: 
100011077(PPP3CB) 100014900(PPP3CA) 100033104(PPP3CC)
SHR: 
100915297(PPP3CC) 100917281(PPP3CB) 100918408(PPP3CA)
OAA: 
100073776(PPP3CB) 100083890(PPP3CA) 100084594 100087467(PPP3CC)
GGA: 
378890(PPP3CB) 395113(PPP3CA)
MGP: 
100543676(PPP3CB) 100547009(PPP3CA)
APLA: 
101792272(PPP3CA) 101794308(PPP3CC) 101800684(PPP3CB)
TGU: 
100222189(PPP3CB) 100225527(PPP3CC) 100232244(PPP3CA)
FAB: 
101807808(PPP3CC) 101813689(PPP3CB) 101818111(PPP3CA)
PHI: 
102100025(PPP3CC) 102106610(PPP3CB) 102109818(PPP3CA)
FPG: 
101914455(PPP3CA) 101917506(PPP3CC) 101918536(PPP3CB)
FCH: 
102048177(PPP3CB) 102052148(PPP3CC) 102053077(PPP3CA)
CLV: 
102086447(PPP3CA) 102088936(PPP3CC) 102096117(PPP3CB)
ASN: 
102377124(PPP3CC) 102382032(PPP3CB) 102386011(PPP3CA)
AMJ: 
102573328(PPP3CB) 102576061(PPP3CC) 102576759(PPP3CA)
PSS: 
102445775(PPP3CC) 102453558(PPP3CB) 102457798(PPP3CA)
CMY: 
102929773(PPP3CA) 102931885(PPP3CB) 102941746(PPP3CC)
ACS: 
100552158(ppp3cc) 100555622(ppp3ca) 100562089(ppp3cb)
PBI: 
103052619(PPP3CC) 103059540(PPP3CA)
XLA: 
380507(ppp3ca) 432106(ppp3cb) 447196(ppp3ca)
XTR: 
100037840(ppp3cb) 100037857(ppp3cc) 100144934(ppp3ca)
DRE: 
550554(ppp3cb) 557926(ppp3cca) 565241(ppp3ccb) 794574(ppp3ca)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
103177620(ppp3ca) 103185841(ppp3cb) 103186967 103187759(ppp3cc)
CIN: 
SPU: 
588695(ppp3ca)
DME: 
Dmel_CG1455(CanA1) Dmel_CG9819(CanA-14F) Dmel_CG9842(Pp2B-14D)
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
CQU: 
AME: 
411046(GB12904)
NVI: 
TCA: 
BMOR: 
692577(Cna)
API: 
PHU: 
ISC: 
CEL: 
CBR: 
CBG08362(Cbr-tax-6)
BMY: 
LOA: 
TSP: 
HRO: 
LGI: 
SMM: 
NVE: 
HMG: 
100205420(ppp3ca)
TAD: 
AQU: 
PXB: 
SCE: 
YLR433C(CNA1) YML057W(CMP2)
AGO: 
ERC: 
KLA: 
LTH: 
VPO: 
ZRO: 
CGR: 
NCS: 
NCAS_0A02820(NCAS0A02820) NCAS_0J01890(NCAS0J01890)
NDI: 
NDAI_0J02460(NDAI0J02460)
TPF: 
TPHA_0B00570(TPHA0B00570)
TBL: 
TBLA_0E04600(TBLA0E04600) TBLA_0G02130(TBLA0G02130)
TDL: 
TDEL_0D01050(TDEL0D01050)
KAF: 
KAFR_0I00480(KAFR0I00480)
PPA: 
DHA: 
PIC: 
PGU: 
SPAA: 
LEL: 
CAL: 
CTP: 
COT: 
CDU: 
CTEN: 
YLI: 
CLU: 
NCR: 
SMP: 
PAN: 
TTT: 
MTM: 
CTHR: 
MGR: 
TMN: 
FGR: 
NHE: 
TRE: 
MAW: 
MAJ: 
CMT: 
VAL: 
ELA: 
SSL: 
BFU: 
MBE: 
ANI: 
AFM: 
AOR: 
AOR_1_962084(AO090020000552)
ANG: 
ANI_1_444064(An07g03620)
AFV: 
ACT: 
NFI: 
PCS: 
CIM: 
CPW: 
PBL: 
URE: 
ABE: 
TVE: 
AJE: 
PNO: 
PTE: 
BZE: 
BSC: 
BOR: 
ZTR: 
PFJ: 
BCOM: 
NPA: 
TML: 
SPO: 
CNE: 
CNB: 
CGI: 
TMS: 
PPL: 
DSQ: 
PCO: 
SHS: 
PSQ: 
ADL: 
FME: 
GTR: 
LBC: 
MPR: 
MRR: 
CCI: 
SCM: 
ABP: 
AGABI1DRAFT115816(AGABI1DRAFT_115816) AGABI1DRAFT76707(AGABI1DRAFT_76707)
ABV: 
AGABI2DRAFT194461(AGABI2DRAFT_194461) AGABI2DRAFT77099(AGABI2DRAFT_77099)
CPUT: 
SLA: 
UMA: 
PFP: 
MGL: 
PGR: 
MLR: 
WSE: 
MBR: 
DDI: 
DPP: 
DFA: 
DFA_02232(canA)
EHI: 
EHI_017600(126.t00023) EHI_048590(107.t00006) EHI_050920(60.t00035) EHI_051020(5.t00022) EHI_069970(393.t00001) EHI_109570 EHI_115710(355.t00003) EHI_118600 EHI_136190(33.t00008) EHI_146350(260.t00008) EHI_151180(2.t00018) EHI_167510(69.t00006) EHI_178030(261.t00011) EHI_199120(87.t00027)
EDI: 
ACAN: 
PFA: 
PFD: 
PFH: 
PYO: 
PCB: 
PBE: 
PKN: 
PVX: 
PCY: 
CPV: 
CHO: 
TGO: 
TET: 
PTM: 
PIF: 
TBR: 
TCR: 
LMA: 
LIF: 
LDO: 
LMI: 
LBZ: 
NGR: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Rusnak F, Mertz P
  Title
Calcineurin: form and function.
  Journal
Physiol Rev 80:1483-521 (2000)

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