KEGG   ORTHOLOGY: K04354Help
Entry
K04354                      KO                                     

Name
PPP2R2
Definition
serine/threonine-protein phosphatase 2A regulatory subunit B
Pathway
mRNA surveillance pathway
Cell cycle - yeast
PI3K-Akt signaling pathway
AMPK signaling pathway
Adrenergic signaling in cardiomyocytes
Hippo signaling pathway
Hippo signaling pathway - fly
Tight junction
Dopaminergic synapse
Chagas disease (American trypanosomiasis)
Hepatitis C
Disease
H00063  
Spinocerebellar ataxia (SCA)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Genetic Information Processing
  Translation
   03015 mRNA surveillance pathway
    K04354  PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
 Environmental Information Processing
  Signal transduction
   04390 Hippo signaling pathway
    K04354  PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
   04391 Hippo signaling pathway -fly
    K04354  PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
   04151 PI3K-Akt signaling pathway
    K04354  PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
   04152 AMPK signaling pathway
    K04354  PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
 Cellular Processes
  Cell growth and death
   04111 Cell cycle - yeast
    K04354  PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
  Cellular commiunity
   04530 Tight junction
    K04354  PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
 Organismal Systems
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K04354  PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
  Nervous system
   04728 Dopaminergic synapse
    K04354  PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
 Human Diseases
  Infectious diseases
   05160 Hepatitis C
    K04354  PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
   05142 Chagas disease (American trypanosomiasis)
    K04354  PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
Protein phosphatases and associated proteins [BR:ko01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-2 (PP2A)
    Regulatory subunits
     K04354  PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
Chromosome [BR:ko03036]
 Eukaryotic Type
  Centromeric chromatin formation proteins
   Other centromeric chromatin formation proteins
    PP2A (protein phosphatase 2A)
     K04354  PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
5520(PPP2R2A) 5521(PPP2R2B) 5522(PPP2R2C) 55844(PPP2R2D)
PTR: 
461101(PPP2R2C) 462170(PPP2R2B) 464068(PPP2R2A) 466265(PPP2R2D)
PPS: 
100968814(PPP2R2D) 100983884(PPP2R2C) 100990236(PPP2R2B) 100991998(PPP2R2A)
GGO: 
101129571(PPP2R2A) 101132841(PPP2R2D) 101135043(PPP2R2B) 101140471(PPP2R2C)
PON: 
100174027(PPP2R2B) 100436819(PPP2R2D) 100443527(PPP2R2A)
NLE: 
100583131(PPP2R2C) 100583311(PPP2R2A) 100584267(PPP2R2B) 100585667(PPP2R2D)
MCC: 
699520(PPP2R2D) 706988(PPP2R2B) 711023(PPP2R2C) 711920
MCF: 
101926197(PPP2R2A) 101926525 102125257(PPP2R2B) 102142696(PPP2R2D)
CJC: 
100385385(PPP2R2D) 100386371(PPP2R2C) 100407485(PPP2R2A) 100407627(PPP2R2B)
MMU: 
269643(Ppp2r2c) 52432(Ppp2r2d) 71978(Ppp2r2a) 72930(Ppp2r2b)
RNO: 
117104(Ppp2r2a) 117256(Ppp2r2c) 246255(Ppp2r2d) 60660(Ppp2r2b)
CGE: 
100750924(Ppp2r2c) 100758873(Ppp2r2a) 100763205(Ppp2r2b) 100774343(Ppp2r2d) 103162642
HGL: 
101700573(Ppp2r2b) 101708645(Ppp2r2a) 101709789(Ppp2r2d) 101711517(Ppp2r2c)
TUP: 
102470174(PPP2R2C) 102480799(PPP2R2D) 102485560(PPP2R2B) 102488546(PPP2R2A)
CFA: 
477374(PPP2R2A) 478053(PPP2R2B) 491587(PPP2R2D) 610262(PPP2R2C)
AML: 
UMR: 
103658340(PPP2R2C) 103658377(PPP2R2D) 103663691(PPP2R2B) 103673291(PPP2R2A)
FCA: 
101084083(PPP2R2B) 101086093(PPP2R2D) 101091784(PPP2R2C) 101099546(PPP2R2A)
PTG: 
102949872(PPP2R2D) 102951261(PPP2R2B) 102952971(PPP2R2A) 102970289(PPP2R2C)
BTA: 
508045(PPP2R2A) 509290(PPP2R2B) 782110(PPP2R2C)
BOM: 
102272209(PPP2R2C) 102287363(PPP2R2B) 102287455(PPP2R2A)
PHD: 
102323130(PPP2R2A) 102338279(PPP2R2B) 102338662(PPP2R2C)
CHX: 
102170971(PPP2R2B) 102181952(PPP2R2A) 102188298(PPP2R2C)
OAS: 
101102148(PPP2R2C) 101108180(PPP2R2D) 101110299(PPP2R2A) 101113409(PPP2R2B)
SSC: 
397089(PPP2R2B) 397090(PPP2R2A)
CFR: 
102509034(PPP2R2C) 102513309(PPP2R2D) 102514622(PPP2R2A) 102517457(PPP2R2B)
BACU: 
103001451(PPP2R2C) 103003377(PPP2R2B) 103015446(PPP2R2D) 103020854(PPP2R2A)
LVE: 
103070944(PPP2R2C) 103075527(PPP2R2B) 103085298(PPP2R2A) 103090378(PPP2R2D)
ECB: 
100051737(PPP2R2D) 100059955(PPP2R2A) 100060957(PPP2R2B) 100070133(PPP2R2C)
MYB: 
102238990(PPP2R2A) 102240425(PPP2R2B) 102243537(PPP2R2C) 102254637(PPP2R2D)
MYD: 
102756870(PPP2R2A) 102772844(PPP2R2B) 102773953(PPP2R2D) 102774976(PPP2R2C)
PALE: 
102882824(PPP2R2A) 102888692(PPP2R2B) 102892945
MDO: 
100014202(PPP2R2C) 100018121(PPP2R2A) 100023749(PPP2R2B) 100023958(PPP2R2D)
SHR: 
100922930(PPP2R2C) 100931978(PPP2R2A) 100933266(PPP2R2B) 100935274(PPP2R2D)
OAA: 
GGA: 
416350(PPP2R2B) 419523(PPP2R2A) 422858(PPP2R2C) 423970(PPP2R2D)
MGP: 
APLA: 
101792196(PPP2R2A) 101797307(PPP2R2B) 101798527 101801149(PPP2R2C)
TGU: 
100225233(PPP2R2B) 100225699(PPP2R2C) 100232829(PPP2R2A)
FAB: 
101810844(PPP2R2B) 101812324(PPP2R2A) 101814165(PPP2R2D) 101819160(PPP2R2C)
PHI: 
102105305(PPP2R2B) 102105717(PPP2R2C) 102107324(PPP2R2A) 102114376(PPP2R2D)
FPG: 
101921274(PPP2R2B) 101921738(PPP2R2D) 101921932(PPP2R2C) 101924330(PPP2R2A)
FCH: 
102047212(PPP2R2C) 102050344(PPP2R2A) 102050692(PPP2R2B) 102053115(PPP2R2D)
CLV: 
102090341(PPP2R2C) 102091831(PPP2R2B) 102094079(PPP2R2A) 102098008(PPP2R2D)
ASN: 
102374906(PPP2R2B) 102380229 102380791(PPP2R2C) 102385445(PPP2R2A)
AMJ: 
102559987(PPP2R2C) 102572311(PPP2R2A) 102574203(PPP2R2D) 102574435(PPP2R2B)
PSS: 
102449014(PPP2R2A) 102449572 102450062 102457546(PPP2R2B) 102461089(PPP2R2C)
CMY: 
102930979(PPP2R2D) 102931164(PPP2R2C) 102931325(PPP2R2A) 102938384(PPP2R2B)
ACS: 
100555366(ppp2r2a) 100558872(ppp2r2c) 100563742(ppp2r2b) 100567969(ppp2r2d)
PBI: 
103049560(PPP2R2A) 103050725(PPP2R2C) 103055041(PPP2R2B) 103063571(PPP2R2D)
XLA: 
379305(ppp2r2d) 394301(ppp2r2b) 399328(ppp2r2a)
XTR: 
100490097(ppp2r2c) 448324(ppp2r2d) 496486(ppp2r2a) 549212(ppp2r2b)
DRE: 
100002802(ppp2r2ca) 327263(ppp2r2d) 405816(ppp2r2d) 558752(ppp2r2a) 558810(ppp2r2bb) 558884 559392
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102350099(PPP2R2B) 102355760(PPP2R2C) 102362122(PPP2R2A) 102364042(PPP2R2D)
CMK: 
103177292(ppp2r2b) 103180386(ppp2r2d) 103181323(ppp2r2c) 103191459
BFO: 
CIN: 
SPU: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
CQU: 
AME: 
410604(tws)
NVI: 
TCA: 
BMOR: 
API: 
PHU: 
ISC: 
CEL: 
CBR: 
CBG03807(Cbr-sur-6)
BMY: 
LOA: 
TSP: 
HRO: 
LGI: 
SMM: 
NVE: 
HMG: 
TAD: 
AQU: 
ATH: 
AT1G17720(ATB_BETA) AT1G51690(B_ALPHA)
ALY: 
CRB: 
EUS: 
CIT: 
CIC: 
TCC: 
GMX: 
PVU: 
MTR: 
CAM: 
FVE: 
PPER: 
PMUM: 
MDM: 
CSV: 
CMO: 
RCU: 
POP: 
POPTR_0001s20400g POPTR_0003s02900g POPTR_0006s24710g(POPTRDRAFT_1081434) POPTR_0015s09060g(POPTRDRAFT_575190) POPTR_0018s05050g(POPTRDRAFT_1105642)
VVI: 
SLY: 
SOT: 
OSA: 
DOSA: 
Os01t0600200-01(Os01g0600200) Os02t0224200-01(Os02g0224200) Os02t0617600-01(Os02g0617600) Os06t0563300-01(Os06g0563300)
OBR: 
BDI: 
SBI: 
SORBI_03g027000(SORBIDRAFT_03g027000) SORBI_04g026100(SORBIDRAFT_04g026100) SORBI_10g022260(SORBIDRAFT_10g022260)
ZMA: 
SITA: 
ATR: 
s00036p00236520(AMTR_s00036p00236520) s00085p00151790(AMTR_s00085p00151790) s00169p00051950(AMTR_s00169p00051950)
SMO: 
PPP: 
CRE: 
VCN: 
OLU: 
OTA: 
BPG: 
MIS: 
MPP: 
CSL: 
CVR: 
CME: 
GSL: 
SCE: 
YGL190C(CDC55)
AGO: 
ERC: 
KLA: 
LTH: 
VPO: 
ZRO: 
CGR: 
NCS: 
NCAS_0B04470(NCAS0B04470) NCAS_0B05510(NCAS0B05510)
NDI: 
NDAI_0B01910(NDAI0B01910) NDAI_0B02680(NDAI0B02680)
TPF: 
TPHA_0H00350(TPHA0H00350)
TBL: 
TBLA_0D02160(TBLA0D02160)
TDL: 
TDEL_0B04610(TDEL0B04610)
KAF: 
KAFR_0C02950(KAFR0C02950)
PPA: 
DHA: 
PIC: 
PGU: 
SPAA: 
LEL: 
CAL: 
CaO19.1468(CDC55) CaO19.9043(CDC55)
CTP: 
COT: 
CDU: 
CTEN: 
CLU: 
NCR: 
SMP: 
PAN: 
TTT: 
MTM: 
CTHR: 
MGR: 
TMN: 
FGR: 
NHE: 
TRE: 
MAW: 
MAJ: 
CMT: 
VAL: 
ELA: 
SSL: 
BFU: 
MBE: 
ANI: 
AFM: 
AOR: 
AOR_1_1032174(AO090005000590)
ANG: 
ANI_1_942144(An16g07130)
AFV: 
ACT: 
NFI: 
PCS: 
CIM: 
CPW: 
PBL: 
URE: 
ABE: 
TVE: 
AJE: 
PNO: 
PTE: 
BZE: 
BSC: 
BOR: 
ZTR: 
MYCGRDRAFT_67389(MgPP2Aregb1)
PFJ: 
BCOM: 
NPA: 
TML: 
SPO: 
CNE: 
CNB: 
CGI: 
TMS: 
DSQ: 
SHS: 
PCO: 
PSQ: 
ADL: 
FME: 
GTR: 
LBC: 
MPR: 
MRR: 
CCI: 
SCM: 
ABP: 
AGABI1DRAFT83170(AGABI1DRAFT_83170)
ABV: 
AGABI2DRAFT136742(AGABI2DRAFT_136742)
CPUT: 
SLA: 
UMA: 
PFP: 
MGL: 
PGR: 
MLR: 
WSE: 
ECU: 
EIN: 
EHE: 
NCE: 
MBR: 
DDI: 
DPP: 
DFA: 
EHI: 
EHI_148170(1.t00140)
EDI: 
ACAN: 
TET: 
PTM: 
PIF: 
EHX: 
GTT: 
TBR: 
TCR: 
LMA: 
LIF: 
LDO: 
LMI: 
LBZ: 
NGR: 
TVA: 
GLA: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Lechward K, Awotunde OS, Swiatek W, Muszynska G
  Title
Protein phosphatase 2A: variety of forms and diversity of functions.
  Journal
Acta Biochim Pol 48:921-33 (2001)
Reference
  Authors
Sontag E
  Title
Protein phosphatase 2A: the Trojan Horse of cellular signaling.
  Journal
Cell Signal 13:7-16 (2001)
Reference
  Authors
Janssens V, Goris J
  Title
Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling.
  Journal
Biochem J 353:417-39 (2001)

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