KEGG   ORTHOLOGY: K04357Help
Entry
K04357                      KO                                     

Name
EGF
Definition
epidermal growth factor
Pathway
EGFR tyrosine kinase inhibitor resistance
MAPK signaling pathway
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Cytokine-cytokine receptor interaction
HIF-1 signaling pathway
FoxO signaling pathway
Phospholipase D signaling pathway
Endocytosis
PI3K-Akt signaling pathway
Focal adhesion
Gap junction
Regulation of actin cytoskeleton
Hepatitis C
Pathways in cancer
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Bladder cancer
Non-small cell lung cancer
Breast cancer
Choline metabolism in cancer
Disease
H00018  
Gastric cancer
H01210  
Hypomagnesemia
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K04357  EGF; epidermal growth factor
   04015 Rap1 signaling pathway
    K04357  EGF; epidermal growth factor
   04010 MAPK signaling pathway
    K04357  EGF; epidermal growth factor
   04012 ErbB signaling pathway
    K04357  EGF; epidermal growth factor
   04066 HIF-1 signaling pathway
    K04357  EGF; epidermal growth factor
   04068 FoxO signaling pathway
    K04357  EGF; epidermal growth factor
   04072 Phospholipase D signaling pathway
    K04357  EGF; epidermal growth factor
   04151 PI3K-Akt signaling pathway
    K04357  EGF; epidermal growth factor
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K04357  EGF; epidermal growth factor
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    K04357  EGF; epidermal growth factor
  Cell motility
   04810 Regulation of actin cytoskeleton
    K04357  EGF; epidermal growth factor
  Cellular community - eukaryotes
   04510 Focal adhesion
    K04357  EGF; epidermal growth factor
   04540 Gap junction
    K04357  EGF; epidermal growth factor
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K04357  EGF; epidermal growth factor
   05231 Choline metabolism in cancer
    K04357  EGF; epidermal growth factor
   05212 Pancreatic cancer
    K04357  EGF; epidermal growth factor
   05214 Glioma
    K04357  EGF; epidermal growth factor
   05218 Melanoma
    K04357  EGF; epidermal growth factor
   05219 Bladder cancer
    K04357  EGF; epidermal growth factor
   05215 Prostate cancer
    K04357  EGF; epidermal growth factor
   05213 Endometrial cancer
    K04357  EGF; epidermal growth factor
   05224 Breast cancer
    K04357  EGF; epidermal growth factor
   05223 Non-small cell lung cancer
    K04357  EGF; epidermal growth factor
  Infectious diseases
   05160 Hepatitis C
    K04357  EGF; epidermal growth factor
  Drug resistance
   01521 EGFR tyrosine kinase inhibitor resistance
    K04357  EGF; epidermal growth factor
Cytokines [BR:ko04052]
 PDGF family
  Other growth factors
   K04357  EGF; epidermal growth factor
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
1950(EGF)
PTR: 
461435(EGF)
PPS: 
GGO: 
PON: 
NLE: 
MCC: 
698619(EGF)
MCF: 
CSAB: 
RRO: 
CJC: 
SBQ: 
MMU: 
13645(Egf)
RNO: 
25313(Egf)
CGE: 
NGI: 
HGL: 
OCU: 
TUP: 
CFA: 
403657(EGF)
AML: 
UMR: 
FCA: 
493978(EGF)
PTG: 
BTA: 
530315(EGF)
BOM: 
PHD: 
CHX: 
OAS: 
SSC: 
397083(EGF)
CFR: 
BACU: 
LVE: 
ECB: 
MYB: 
MYD: 
PALE: 
LAV: 
MDO: 
SHR: 
OAA: 
GGA: 
408035(EGF)
MGP: 
CJO: 
APLA: 
TGU: 
GFR: 
FAB: 
PHI: 
CCW: 
FPG: 
FCH: 
CLV: 
AAM: 
ASN: 
AMJ: 
PSS: 
CMY: 
ACS: 
PBI: 
GJA: 
XTR: 
DRE: 
403045(egf)
TRU: 
TNG: 
MZE: 
OLA: 
XMA: 
SASA: 
LCM: 
CMK: 
SKO: 
ADF: 
AQU: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:3491360
  Authors
Bell GI, Fong NM, Stempien MM, Wormsted MA, Caput D, Ku LL, Urdea MS, Rall LB, Sanchez-Pescador R
  Title
Human epidermal growth factor precursor: cDNA sequence, expression in vitro and gene organization.
  Journal
Nucleic Acids Res 14:8427-46 (1986)
  Sequence
[hsa:1950]
Reference
  Authors
Hermann PM, van Kesteren RE, Wildering WC, Painter SD, Reno JM, Smith JS, Kumar SB, Geraerts WP, Ericsson LH, Smit AB, Bulloch AG, Nagle GT
  Title
Neurotrophic actions of a novel molluscan epidermal growth factor.
  Journal
J Neurosci 20:6355-64 (2000)
  Sequence
[mmu:13645]

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