KEGG   ORTHOLOGY: K04363Help
Entry
K04363                      KO                                     
Name
PDGFRA
Definition
platelet-derived growth factor receptor alpha [EC:2.7.10.1]
Pathway
MAPK signaling pathway
Calcium signaling pathway
Cytokine-cytokine receptor interaction
Endocytosis
PI3K-Akt signaling pathway
Focal adhesion
Gap junction
Regulation of actin cytoskeleton
HTLV-I infection
Pathways in cancer
Glioma
Prostate cancer
Melanoma
Disease
H00042  
Glioma
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K04363  PDGFRA; platelet-derived growth factor receptor alpha
   04020 Calcium signaling pathway
    K04363  PDGFRA; platelet-derived growth factor receptor alpha
   04151 PI3K-Akt signaling pathway
    K04363  PDGFRA; platelet-derived growth factor receptor alpha
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K04363  PDGFRA; platelet-derived growth factor receptor alpha
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    K04363  PDGFRA; platelet-derived growth factor receptor alpha
  Cell motility
   04810 Regulation of actin cytoskeleton
    K04363  PDGFRA; platelet-derived growth factor receptor alpha
  Cell communication
   04510 Focal adhesion
    K04363  PDGFRA; platelet-derived growth factor receptor alpha
   04540 Gap junction
    K04363  PDGFRA; platelet-derived growth factor receptor alpha
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K04363  PDGFRA; platelet-derived growth factor receptor alpha
   05214 Glioma
    K04363  PDGFRA; platelet-derived growth factor receptor alpha
   05218 Melanoma
    K04363  PDGFRA; platelet-derived growth factor receptor alpha
   05215 Prostate cancer
    K04363  PDGFRA; platelet-derived growth factor receptor alpha
  Infectious diseases
   05166 HTLV-I infection
    K04363  PDGFRA; platelet-derived growth factor receptor alpha
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     K04363  PDGFRA; platelet-derived growth factor receptor alpha
Protein kinases [BR:ko01001]
 Tyrosine protein kinases
  PDGFR family
   K04363  PDGFRA; platelet-derived growth factor receptor alpha
Enzyme-linked receptors [BR:ko01020]
 Receptor tyrosine kinases
  RTK class III (PDGF receptor family)
   K04363  PDGFRA; platelet-derived growth factor receptor alpha
Cytokine receptors [BR:ko04050]
 Receptor tyrosine kinase
  RTK class III (PDGF receptor family)
   K04363  PDGFRA; platelet-derived growth factor receptor alpha
Cellular antigens [BR:ko04090]
 Proteins
  K04363  CD140a, PDGFRA; platelet-derived growth factor receptor, alpha polypeptide
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
5156(PDGFRA)
PTR: 
461318(PDGFRA)
PPS: 
100982337(PDGFRA)
GGO: 
101124928(PDGFRA)
PON: 
100431735(PDGFRA)
MCC: 
697002(PDGFRA)
MMU: 
18595(Pdgfra)
RNO: 
25267(Pdgfra)
CFA: 
442860(PDGFRA)
AML: 
100464991(PDGFRA)
FCA: 
101090765(PDGFRA)
BTA: 
282301(PDGFRA)
ECB: 
100059815(PDGFRA)
MDO: 
100013088(PDGFRA)
SHR: 
100925116(PDGFRA)
OAA: 
100084432(PDGFRA)
GGA: 
395509(PDGFRA)
MGP: 
100542010
TGU: 
100218386(PDGFRA)
ACS: 
100565834
XLA: 
380245(pdgfra)
XTR: 
100124862
TRU: 
101073543
OLA: 
100049280(pdgfr)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Acconcia F, Sigismund S, Polo S
  Title
Ubiquitin in trafficking: the network at work.
  Journal
Exp Cell Res 315:1610-8 (2009)
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