KEGG   ORTHOLOGY: K04372Help
Entry
K04372                      KO                                     

Name
MKNK, MNK
Definition
MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
Pathway
MAPK signaling pathway
HIF-1 signaling pathway
Insulin signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K04372  MKNK, MNK; MAP kinase interacting serine/threonine kinase
   04066 HIF-1 signaling pathway
    K04372  MKNK, MNK; MAP kinase interacting serine/threonine kinase
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    K04372  MKNK, MNK; MAP kinase interacting serine/threonine kinase
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K04372  MKNK, MNK; MAP kinase interacting serine/threonine kinase
Protein kinases [BR:ko01001]
 Serine/threonine protein kinases: CAMK group
  MAPKAPK family [Table]
   K04372  MKNK, MNK; MAP kinase interacting serine/threonine kinase
BRITE hierarchy
Genes
HSA: 
2872(MKNK2) 8569(MKNK1)
PTR: 
455561(MKNK2) 469189(MKNK1)
PPS: 
100978591(MKNK2) 100980382(MKNK1)
GGO: 
101136046(MKNK1) 101144950(MKNK2)
PON: 
100446049(MKNK2) 100448005(MKNK1)
MCC: 
710061(MKNK1) 721436(MKNK2)
MCF: 
102129375(MKNK1) 102138091(MKNK2)
MMU: 
17346(Mknk1) 17347(Mknk2)
RNO: 
299618(Mknk2) 500526(Mknk1)
CGE: 
100759870(Mknk1) 100769766(Mknk2)
HGL: 
101716935(Mknk2) 101723982(Mknk1)
TUP: 
102491698(MKNK1) 102493702(MKNK2)
CFA: 
482509(MKNK1) 612212(MKNK2)
AML: 
FCA: 
101082505(MKNK1) 101087206(MKNK2)
BTA: 
525647(MKNK1) 538519(MKNK2)
BOM: 
102269500(MKNK2) 102284499(MKNK1)
PHD: 
102318386(MKNK2) 102325800(MKNK1)
CHX: 
102174453(MKNK1) 102180932(MKNK2)
SSC: 
100233194(MKNK1) 100517077(MKNK2)
CFR: 
102503567(MKNK1) 102521828(MKNK2)
ECB: 
100064521(MKNK1)
MYB: 
102241394(MKNK2) 102259569(MKNK1)
MDO: 
SHR: 
100917828(MKNK2) 100931320(MKNK1)
OAA: 
GGA: 
429269(MKNK2) 771961(MKNK1)
MGP: 
TGU: 
FAB: 
101806775(MKNK2) 101809741(MKNK1)
PHI: 
102100999(MKNK2) 102114105(MKNK1)
APLA: 
101791054(MKNK2) 101794448(MKNK1)
FPG: 
101912281(MKNK1) 101917525(MKNK2)
FCH: 
102045852(MKNK1) 102053617(MKNK2)
CLV: 
102086177(MKNK1) 102088437(MKNK2)
ASN: 
PSS: 
102454088(MKNK1) 102456802(MKNK2)
ACS: 
XLA: 
100036803 387327(mknk1) 399068(mknk2)
XTR: 
493413(mknk1) 780232(mknk2)
DRE: 
334167(mknk2a) 373121(mknk2b) 555974(mknk1)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102345480(MKNK1) 102352116(MKNK2)
BFO: 
CIN: 
SPU: 
575733(mnk1)
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
CQU: 
AME: 
412470(Lk6)
NVI: 
TCA: 
BMOR: 
API: 
PHU: 
ISC: 
CEL: 
CBR: 
CBG03074(Cbr-mnk-1)
BMY: 
LOA: 
TSP: 
NVE: 
HMG: 
AQU: 
MBR: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Parra JL, Buxade M, Proud CG
  Title
Features of the catalytic domains and C termini of the MAPK signal-integrating kinases Mnk1 and Mnk2 determine their differing activities and regulatory properties.
  Journal
J Biol Chem 280:37623-33 (2005)

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