KEGG   ORTHOLOGY: K04373Help
Entry
K04373                      KO                                     
Name
RPS6KA, RSK2
Definition
p90 ribosomal S6 kinase [EC:2.7.11.1]
Pathway
MAPK signaling pathway
Oocyte meiosis
mTOR signaling pathway
Long-term potentiation
Neurotrophin signaling pathway
Progesterone-mediated oocyte maturation
Disease
H00480  
Non-syndromic X-linked mental retardation
H00574  
Coffin-Lowry syndrome (CLS)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K04373  RPS6KA, RSK2; p90 ribosomal S6 kinase
   04150 mTOR signaling pathway
    K04373  RPS6KA, RSK2; p90 ribosomal S6 kinase
 Cellular Processes
  Cell growth and death
   04114 Oocyte meiosis
    K04373  RPS6KA, RSK2; p90 ribosomal S6 kinase
 Organismal Systems
  Endocrine system
   04914 Progesterone-mediated oocyte maturation
    K04373  RPS6KA, RSK2; p90 ribosomal S6 kinase
  Nervous system
   04720 Long-term potentiation
    K04373  RPS6KA, RSK2; p90 ribosomal S6 kinase
   04722 Neurotrophin signaling pathway
    K04373  RPS6KA, RSK2; p90 ribosomal S6 kinase
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K04373  RPS6KA, RSK2; p90 ribosomal S6 kinase
Protein kinases [BR:ko01001]
 Serine/threonine protein kinases: AGC group
  RSK family
   K04373  RPS6KA, RSK2; p90 ribosomal S6 kinase
BRITE hierarchy
Genes
HSA: 
27330(RPS6KA6) 6195(RPS6KA1) 6196(RPS6KA2) 6197(RPS6KA3)
PTR: 
450110(RPS6KA3) 456664(RPS6KA1) 463127(RPS6KA2) 743327(RPS6KA6)
PPS: 
100967605(RPS6KA6) 100970504(RPS6KA1) 100971242(RPS6KA2) 100986115(RPS6KA3)
GGO: 
101128748(RPS6KA1) 101131367(RPS6KA6) 101132937(RPS6KA2) 101132954(RPS6KA3)
PON: 
100438726(RPS6KA6) 100450481(RPS6KA2) 100451332(RPS6KA3) 100459459(RPS6KA1)
MCC: 
MMU: 
110651(Rps6ka3) 20111(Rps6ka1) 20112(Rps6ka2) 67071(Rps6ka6)
RNO: 
117269(Rps6ka2) 317203(Rps6ka6) 501560(Rps6ka3) 81771(Rps6ka1)
CFA: 
487353(RPS6KA1) 491768(RPS6KA3) 491989(RPS6KA6) 612448(RPS6KA2)
AML: 
FCA: 
101082546(RPS6KA3) 101086492(RPS6KA1) 101094163(RPS6KA6) 101099466(RPS6KA2)
BTA: 
511190(RPS6KA3) 517953(RPS6KA2) 526227(RPS6KA6) 533908(RPS6KA1)
SSC: 
100515286 100522174(RPS6KA3) 100522294(RPS6KA6) 100523972(RPS6KA1)
ECB: 
100050176(RPS6KA2) 100057166(RPS6KA1) 100058911
MDO: 
100011215 100016076(RPS6KA1) 100017114 100028312(RPS6KA2)
SHR: 
100923157(RPS6KA1) 100928498(RPS6KA6) 100931566(RPS6KA3) 100931854(RPS6KA2)
OAA: 
100077380 100083378 100088568
GGA: 
386579(RPS6KA1) 418605(RPS6KA3) 421570(RPS6KA2) 422273(RPS6KA6)
MGP: 
100540546 100541690 100547002 100548475(RPS6KA3)
TGU: 
100217905(RPS6KA6) 100217995 100227972(RPS6KA3) 100229905(RPS6KA2)
ACS: 
100552319 100553161
XLA: 
399376(rps6ka3) 443729(rps6ka6) 445821(rps6ka1)
XTR: 
100144704(rps6ka1) 100488417 100495717(rps6ka2) 100496161
DRE: 
100009657(rps6ka3b) 337670(rps6kal) 338219(rps6ka3a) 571285(rps6ka2) 777728(rps6ka1)
TRU: 
101062814 101069910 101070821 101071645
OLA: 
101165012 101168378 101169648
BFO: 
BRAFLDRAFT_89962
CIN: 
100175855(rps6ka3)
SPU: 
592417(rps6ka3)
DME: 
Dmel_CG17596(S6kII)
DPO: 
Dpse_GA14570
DAN: 
Dana_GF21004
DER: 
Dere_GG19750
DPE: 
Dper_GL13301
DSE: 
Dsec_GM11736
DSI: 
Dsim_GD17550
DWI: 
Dwil_GK25774
DYA: 
Dyak_GE17944(Dyak_S6kII)
DGR: 
Dgri_GH24077
DMO: 
Dmoj_GI14475
DVI: 
Dvir_GJ18812
AGA: 
AgaP_AGAP003040
AAG: 
AaeL_AAEL004474
CQU: 
CpipJ_CPIJ014359
AME: 
411481(S6kII)
NVI: 
100117187(RPS6KA3)
TCA: 
664211
API: 
100163709
PHU: 
Phum_PHUM599900
CEL: 
CELE_T01H8.1(rskn-1)
CBR: 
CBG12516(Cbr-rskn-1)
BMY: 
Bm1_24015
TSP: 
Tsp_10306
SMM: 
Smp_017900
NVE: 
NEMVE_v1g135493
TAD: 
TRIADDRAFT_60987
AQU: 
100634677(Rps6ka3)
MBR: 
MONBRDRAFT_7694
TET: 
TTHERM_00016020
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Anjum R, Blenis J
  Title
The RSK family of kinases: emerging roles in cellular signalling.
  Journal
Nat Rev Mol Cell Biol 9:747-58 (2008)
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