KEGG   ORTHOLOGY: K04374Help
Entry
K04374                      KO                                     

Name
ATF4, CREB2
Definition
cyclic AMP-dependent transcription factor ATF-4
Pathway
MAPK signaling pathway
cGMP-PKG signaling pathway
Protein processing in endoplasmic reticulum
PI3K-Akt signaling pathway
Adrenergic signaling in cardiomyocytes
TNF signaling pathway
Long-term potentiation
Neurotrophin signaling pathway
Cholinergic synapse
Dopaminergic synapse
Insulin secretion
GnRH signaling pathway
Estrogen signaling pathway
Thyroid hormone synthesis
Non-alcoholic fatty liver disease (NAFLD)
Cocaine addiction
Amphetamine addiction
Alcoholism
Hepatitis B
HTLV-I infection
Viral carcinogenesis
Prostate cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Genetic Information Processing
  Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
   04668 TNF signaling pathway
    K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
   04022 cGMP - PKG signaling pathway
    K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
   04151 PI3K-Akt signaling pathway
    K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
 Organismal Systems
  Endocrine system
   04911 Insulin secretion
    K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
   04912 GnRH signaling pathway
    K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
   04915 Estrogen signaling pathway
    K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
   04918 Thyroid hormone synthesis
    K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
  Nervous system
   04725 Cholinergic synapse
    K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
   04728 Dopaminergic synapse
    K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
   04720 Long-term potentiation
    K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
   04722 Neurotrophin signaling pathway
    K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
 Human Diseases
  Cancers
   05203 Viral carcinogenesis
    K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
   05215 Prostate cancer
    K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
  Substance dependence
   05030 Cocaine addiction
    K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
   05031 Amphetamine addiction
    K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
   05034 Alcoholism
    K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
  Infectious diseases
   05166 HTLV-I infection
    K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
   05161 Hepatitis B
    K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
Transcription factors [BR:ko03000]
 Eukaryotic Type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, CRE-BP/ATF
    K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
468(ATF4)
PTR: 
744513(ATF4)
PPS: 
GGO: 
101139584(ATF4)
PON: 
100462459(ATF4)
NLE: 
100588160(ATF4)
MCC: 
703965(ATF4)
MCF: 
102117938(ATF4)
CJC: 
100392193(ATF4)
MMU: 
11911(Atf4)
RNO: 
79255(Atf4)
CGE: 
100689386(Atf4)
HGL: 
101724287(Atf4)
TUP: 
102478154(ATF4)
CFA: 
474503(ATF4)
AML: 
UMR: 
103676372(ATF4)
FCA: 
101084297(ATF4)
PTG: 
102950077(ATF4)
BTA: 
509107(ATF4)
BOM: 
102267423(ATF4)
PHD: 
102316221(ATF4)
CHX: 
102185072(ATF4)
OAS: 
100216465(ATF4)
SSC: 
100144302(ATF4)
CFR: 
102508076(ATF4)
BACU: 
103017770(ATF4)
LVE: 
103083306(ATF4)
ECB: 
100070334(ATF4)
MYB: 
102238786(ATF4)
MYD: 
102763654(ATF4)
PALE: 
102896553(ATF4)
MDO: 
100012224(ATF4)
SHR: 
100913697(ATF4)
OAA: 
100089902(ATF4)
GGA: 
395693(ATF4)
MGP: 
APLA: 
TGU: 
FAB: 
101814204(ATF4)
PHI: 
102100681(ATF4)
FPG: 
101921834(ATF4)
FCH: 
102049324(ATF4)
CLV: 
102093872(ATF4)
ASN: 
102369745(ATF4)
AMJ: 
102564186(ATF4)
PSS: 
102449551(ATF4)
CMY: 
102941988(ATF4)
ACS: 
100565177(atf4)
PBI: 
103055721(ATF4)
XLA: 
398804(atf4-a) 734165(atf4-b)
XTR: 
448005(atf4)
DRE: 
406514(atf4b1)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102365086(ATF4)
CMK: 
CIN: 
778545(atf4/5)
AAG: 
AME: 
410226(crc)
NVI: 
TCA: 
658480(ATF4)
API: 
ISC: 
LGI: 
TAD: 
AQU: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Ameri K, Harris AL
  Title
Activating transcription factor 4.
  Journal
Int J Biochem Cell Biol 40:14-21 (2008)
Reference
  Authors
Mayr B, Montminy M
  Title
Transcriptional regulation by the phosphorylation-dependent factor CREB.
  Journal
Nat Rev Mol Cell Biol 2:599-609 (2001)

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