KEGG   ORTHOLOGY: K04382Help
Entry
K04382                      KO                                     

Name
PPP2C
Definition
serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
Pathway
mRNA surveillance pathway
MAPK signaling pathway - fly
Sphingolipid signaling pathway
Cell cycle - yeast
Meiosis - yeast
Oocyte meiosis
PI3K-Akt signaling pathway
AMPK signaling pathway
Adrenergic signaling in cardiomyocytes
TGF-beta signaling pathway
Hippo signaling pathway
Hippo signaling pathway - fly
Tight junction
Dopaminergic synapse
Long-term depression
Chagas disease (American trypanosomiasis)
Hepatitis C
Brite
KEGG Orthology (KO) [BR:ko00001]
 Genetic Information Processing
  Translation
   03015 mRNA surveillance pathway
    K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
 Environmental Information Processing
  Signal transduction
   04013 MAPK signaling pathway - fly
    K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
   04350 TGF-beta signaling pathway
    K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
   04390 Hippo signaling pathway
    K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
   04391 Hippo signaling pathway -fly
    K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
   04071 Sphingolipid signaling pathway
    K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
   04151 PI3K-Akt signaling pathway
    K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
   04152 AMPK signaling pathway
    K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
 Cellular Processes
  Cell growth and death
   04111 Cell cycle - yeast
    K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
   04113 Meiosis - yeast
    K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
   04114 Oocyte meiosis
    K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
  Cellular community - eukaryotes
   04530 Tight junction
    K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
 Organismal Systems
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
  Nervous system
   04728 Dopaminergic synapse
    K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
   04730 Long-term depression
    K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
 Human Diseases
  Infectious diseases
   05160 Hepatitis C
    K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
   05142 Chagas disease (American trypanosomiasis)
    K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
Protein phosphatases and associated proteins [BR:ko01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-2 (PP2A)
    Catalytic subunits
     K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
Chromosome [BR:ko03036]
 Eukaryotic Type
  Centromeric chromatin formation proteins
   Other centromeric chromatin formation proteins
    PP2A (protein phosphatase 2A)
     K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
BRITE hierarchy
Other DBs
COG: 
GO: 
Genes
HSA: 
5515(PPP2CA) 5516(PPP2CB)
PTR: 
100614247(PPP2CA) 464100(PPP2CB) 471633
PPS: 
100976101(PPP2CB) 100981626(PPP2CA) 100987323
GGO: 
101125226(PPP2CB) 101152519(PPP2CA)
PON: 
100437405(PPP2CB) 100461606(PPP2CA)
NLE: 
100585393(PPP2CB) 100596525(PPP2CA)
MCC: 
695118(PPP2CB) 710326(PPP2CA)
MCF: 
101864925(PPP2CA) 102137928(PPP2CB)
CSAB: 
103215586(PPP2CB) 103244545(PPP2CA)
RRO: 
104659809(PPP2CA) 104668221(PPP2CB)
CJC: 
100395261(PPP2CB) 100398536(PPP2CA)
SBQ: 
101028752(PPP2CA) 101037428(PPP2CB)
MMU: 
19052(Ppp2ca) 19053(Ppp2cb)
RNO: 
103694903 24672(Ppp2ca) 24673(Ppp2cb)
CGE: 
100757400(Ppp2cb) 100766084(Ppp2ca)
NGI: 
103729809(Ppp2ca) 103743584(Ppp2cb)
HGL: 
101707511(Ppp2ca) 101726191(Ppp2cb)
OCU: 
100009252(PPP2CA) 100009300(PPP2CB)
TUP: 
102479161(PPP2CA) 102487950 102500173(PPP2CB)
CFA: 
403608(PPP2CA) 482873(PPP2CB)
AML: 
100464293(PPP2CA) 100473021(PPP2CB)
UMR: 
103659105(PPP2CB)
FCA: 
101094667(PPP2CB) 101099271(PPP2CA)
PTG: 
102954008(PPP2CA) 102956715(PPP2CB)
BTA: 
282320(PPP2CA) 524361(PPP2CB)
BOM: 
102266065(PPP2CA) 102279886 102282540(PPP2CB)
PHD: 
102326922(PPP2CB) 102337284(PPP2CA)
CHX: 
102175016(PPP2CA) 102182013(PPP2CB)
OAS: 
101114930(PPP2CB) 443009(PPP2CA)
SSC: 
397136(PPP2CB) 397656(PPP2CA)
CFR: 
102509650(PPP2CB) 106728419(PPP2CA)
BACU: 
103000342(PPP2CB) 103018989(PPP2CA) 103019215
LVE: 
103074714(PPP2CA) 103086967(PPP2CB)
ECB: 
100062224(PPP2CB) 100072780(PPP2CA)
MYB: 
102246010(PPP2CA) 102255371(PPP2CB)
MYD: 
102762679(PPP2CA) 102771922(PPP2CB)
PALE: 
102885289(PPP2CA) 102887013(PPP2CB)
LAV: 
100664132(PPP2CA) 100676230(PPP2CB)
MDO: 
100012652(PPP2CB) 100017519(PPP2CA)
SHR: 
100921980(PPP2CB) 100927043(PPP2CA)
OAA: 
GGA: 
396021(PPP2CB) 416318(PPP2CA)
MGP: 
100546612(PPP2CA) 100549769(PPP2CB)
CJO: 
107313198(PPP2CB) 107320210(PPP2CA)
APLA: 
101799879(PPP2CB) 101803206(PPP2CA)
TGU: 
100190531(PPP2CB) 100218838 100228749(PPP2CA)
GFR: 
102036925(PPP2CA) 102042538(PPP2CB)
FAB: 
101814178(PPP2CA)
PHI: 
102100299(PPP2CA) 102109205(PPP2CB)
CCW: 
104683725(PPP2CA) 104696831(PPP2CB)
FPG: 
101919502(PPP2CA) 101920842(PPP2CB)
FCH: 
102052989(PPP2CB) 102058381(PPP2CA)
CLV: 
AAM: 
ASN: 
102386870(PPP2CB) 102387234(PPP2CA)
AMJ: 
102576713(PPP2CB) 102576911(PPP2CA)
PSS: 
102446185(PPP2CA) 102457538(PPP2CB)
CMY: 
ACS: 
100558622(ppp2cb) 100568233(ppp2ca)
PBI: 
GJA: 
XLA: 
380045(ppp2ca.L) 399343(ppp2cb.L)
XTR: 
394888(ppp2ca) 448031(ppp2cb)
DRE: 
393885(Ppp2ca) 406582(ppp2cb) 550585(ppp2ca)
TRU: 
101065017(ppp2cb) 101068850(ppp2ca)
TNG: 
MZE: 
101470047(ppp2ca) 101479611(ppp2cb) 101487597
OLA: 
XMA: 
102221749(ppp2ca) 102223777 102237558(ppp2cb)
SASA: 
LCM: 
CMK: 
BFO: 
CIN: 
SPU: 
SKO: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
Dsimw501_GD23492(Dsim_GD23492)
DWI: 
DYA: 
Dyak_GE14639(dyak_GLEANR_1487)
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
CQU: 
AME: 
550710(mts)
BIM: 
BTER: 
SOC: 
AEC: 
HST: 
CFO: 
NVI: 
TCA: 
BMOR: 
DPL: 
PXY: 
API: 
PHU: 
DPX: 
ISC: 
CEL: 
CELE_F38H4.9(let-92)
CBR: 
CBG06179(Cbr-let-92)
BMY: 
LOA: 
TSP: 
HRO: 
LGI: 
CRG: 
OBI: 
SMM: 
NVE: 
ADF: 
HMG: 
TAD: 
AQU: 
ATH: 
AT1G10430(PP2A-2) AT1G59830(PP2A-1) AT1G69960(PP2A) AT2G42500(PP2A-3) AT3G58500(PP2A-4)
ALY: 
CRB: 
EUS: 
BRP: 
BNA: 
THJ: 
CIT: 
CIC: 
TCC: 
GRA: 
EGR: 
GMX: 
PVU: 
VRA: 
MTR: 
CAM: 
ADU: 
AIP: 
LJA: 
Lj0g3v0138929.1(Lj0g3v0138929.1) Lj1g3v4763900.1(Lj1g3v4763900.1) Lj2g3v1364780.1(Lj2g3v1364780.1) Lj4g3v2603900.1(Lj4g3v2603900.1)
FVE: 
PPER: 
PMUM: 
MDM: 
PXB: 
CSV: 
CMO: 
RCU: 
JCU: 
POP: 
POPTR_0001s04500g(POPTRDRAFT_547629) POPTR_0003s21320g(POPTRDRAFT_712706) POPTR_0006s21080g(POPTRDRAFT_819327) POPTR_0008s19590g(POPTRDRAFT_657542) POPTR_0010s04890g(POPTRDRAFT_833487) POPTR_0012s07510g(POPTRDRAFT_728788) POPTR_0015s07950g(POPTRDRAFT_824629) POPTR_0016s06190g(POPTRDRAFT_735121)
VVI: 
SLY: 
SPEN: 
SOT: 
SIND: 
BVG: 
NNU: 
OSA: 
4328734(OsJ_005728) 4331747 4334494(OsJ_012457) 4341364(OsJ_020918) 4348601(OsJ_030257)
DOSA: 
Os02t0217600-01(Os02g0217600) Os03t0167700-01(Os03g0167700) Os03t0805300-01(Os03g0805300) Os06t0574500-01(Os06g0574500)
OBR: 
BDI: 
ATS: 
SBI: 
SORBI_01g022230(SORBIDRAFT_01g022230) SORBI_01g046020(SORBIDRAFT_01g046020) SORBI_04g007570(SORBIDRAFT_04g007570) SORBI_10g022710(SORBIDRAFT_10g022710)
ZMA: 
100191189(pco105718) 100191902(pco069598) 100272642 100272765(GRMZM2G119546) 100273101(GRMZM2G038195) 100282302(pco088514(308)) 100282834(GRMZM2G112793) 100283820(GRMZM2G382077) 100381284(GRMZM2G062394) 103649062
SITA: 
PDA: 
EGU: 
MUS: 
ATR: 
SMO: 
PPP: 
CRE: 
VCN: 
OLU: 
OTA: 
BPG: 
MIS: 
MPP: 
CSL: 
CVR: 
APRO: 
CME: 
GSL: 
CCP: 
SCE: 
YDL134C(PPH21) YDL188C(PPH22)
AGO: 
ERC: 
KLA: 
LTH: 
VPO: 
ZRO: 
CGR: 
NCS: 
NCAS_0A13850(NCAS0A13850) NCAS_0E03680(NCAS0E03680)
NDI: 
NDAI_0A02190(NDAI0A02190) NDAI_0A02950(NDAI0A02950)
TPF: 
TPHA_0A03180(TPHA0A03180) TPHA_0P00880(TPHA0P00880)
TBL: 
TBLA_0A05910(TBLA0A05910) TBLA_0F02060(TBLA0F02060)
TDL: 
TDEL_0C02450(TDEL0C02450)
KAF: 
KAFR_0B01120(KAFR0B01120)
PPA: 
DHA: 
PIC: 
PGU: 
SPAA: 
LEL: 
CAL: 
CaO19.1683(PPH21) CaO19.9252(PPH21)
CTP: 
COT: 
CDU: 
CTEN: 
YLI: 
CLU: 
NCR: 
NCU06630(pph-1)
NTE: 
NEUTE1DRAFT59886(NEUTE1DRAFT_59886)
SMP: 
PAN: 
TTT: 
MTM: 
CTHR: 
MGR: 
TMN: 
FGR: 
FPU: 
NHE: 
TRE: 
MAW: 
MAJ: 
CMT: 
VAL: 
VDA: 
ELA: 
SSL: 
BFU: 
MBE: 
ANI: 
AFM: 
AOR: 
AOR_1_264194(AO090012000155)
ANG: 
ANI_1_1608104(An12g02970) ANI_1_58094(An11g00420)
AFV: 
ACT: 
NFI: 
PCS: 
CIM: 
CPW: 
PBL: 
PBN: 
URE: 
ABE: 
TVE: 
AJE: 
PNO: 
PTE: 
BZE: 
BSC: 
BOR: 
ZTR: 
PFJ: 
BCOM: 
NPA: 
TML: 
SPO: 
CNE: 
CNB: 
CGI: 
TMS: 
PPL: 
DSQ: 
PCO: 
SHS: 
HIR: 
PSQ: 
ADL: 
FME: 
GTR: 
LBC: 
MRR: 
CCI: 
SCM: 
ABP: 
AGABI1DRAFT114427(AGABI1DRAFT_114427)
ABV: 
AGABI2DRAFT191462(AGABI2DRAFT_191462)
CPUT: 
SLA: 
WSE: 
WIC: 
UMA: 
PFP: 
MGL: 
PGR: 
MLR: 
ECU: 
EIN: 
EHE: 
ERO: 
NCE: 
MBR: 
SRE: 
DDI: 
DPP: 
EHI: 
EHI_011950(16.t00005)
EDI: 
EIV: 
ACAN: 
PFA: 
PFD: 
PFH: 
PYO: 
PCB: 
PCHAS_082650(PC000855.01.0)
PBE: 
PKN: 
PVX: 
PCY: 
TAN: 
TPV: 
TOT: 
BEQ: 
BBO: 
BBOV_I000740(16.m00696)
CPV: 
CHO: 
TGO: 
TET: 
PTM: 
SMIN: 
v1.2.018382.t1(symbB.v1.2.018382.t1) v1.2.019959.t1(symbB.v1.2.019959.t1) v1.2.019959.t2(symbB.v1.2.019959.t2) v1.2.033440.t1(symbB.v1.2.033440.t1)
PTI: 
TPS: 
AAF: 
PIF: 
PSOJ: 
SPAR: 
EHX: 
GTT: 
TBR: 
Tb927.3.1240(Tb03.1J15.680)
TCR: 
LMA: 
LIF: 
LDO: 
LMI: 
LBZ: 
NGR: 
TVA: 
GLA: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2849764
  Authors
Stone SR, Mayer R, Wernet W, Maurer F, Hofsteenge J, Hemmings BA
  Title
The nucleotide sequence of the cDNA encoding the human lung protein phosphatase 2A alpha catalytic subunit.
  Journal
Nucleic Acids Res 16:11365 (1988)
  Sequence
[hsa:5515]
Reference
PMID:2849765
  Authors
Hemmings BA, Wernet W, Mayer R, Maurer F, Hofsteenge J, Stone SR
  Title
The nucleotide sequence of the cDNA encoding the human lung protein phosphatase 2A beta catalytic subunit.
  Journal
Nucleic Acids Res 16:11366 (1988)
  Sequence
[hsa:5516]

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