KEGG   ORTHOLOGY: K04382Help
Entry
K04382                      KO                                     

Name
PPP2C
Definition
serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
Pathway
mRNA surveillance pathway
Cell cycle - yeast
Meiosis - yeast
Oocyte meiosis
PI3K-Akt signaling pathway
AMPK signaling pathway
Adrenergic signaling in cardiomyocytes
TGF-beta signaling pathway
Hippo signaling pathway
Hippo signaling pathway - fly
Tight junction
Dopaminergic synapse
Long-term depression
Chagas disease (American trypanosomiasis)
Hepatitis C
Brite
KEGG Orthology (KO) [BR:ko00001]
 Genetic Information Processing
  Translation
   03015 mRNA surveillance pathway
    K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
 Environmental Information Processing
  Signal transduction
   04350 TGF-beta signaling pathway
    K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
   04390 Hippo signaling pathway
    K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
   04391 Hippo signaling pathway -fly
    K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
   04151 PI3K-Akt signaling pathway
    K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
   04152 AMPK signaling pathway
    K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
 Cellular Processes
  Cell growth and death
   04111 Cell cycle - yeast
    K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
   04113 Meiosis - yeast
    K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
   04114 Oocyte meiosis
    K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
  Cell communication
   04530 Tight junction
    K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
 Organismal Systems
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
  Nervous system
   04728 Dopaminergic synapse
    K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
   04730 Long-term depression
    K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
 Human Diseases
  Infectious diseases
   05160 Hepatitis C
    K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
   05142 Chagas disease (American trypanosomiasis)
    K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
Protein phosphatases and associated proteins [BR:ko01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-2 (PP2A)
    Catalytic subunits
     K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
Chromosome [BR:ko03036]
 Eukaryotic Type
  Centromeric chromatin formation proteins
   Other centromeric chromatin formation proteins
    PP2A (protein phosphatase 2A)
     K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
5515(PPP2CA) 5516(PPP2CB)
PTR: 
464100(PPP2CB) 471633(PPP2CA)
PPS: 
GGO: 
101125226(PPP2CB) 101152519(PPP2CA)
PON: 
100437405(PPP2CB) 100461606(PPP2CA)
MCC: 
695118(PPP2CB) 710326
MCF: 
MMU: 
19052(Ppp2ca) 19053(Ppp2cb)
RNO: 
100362453 24672(Ppp2ca) 24673(Ppp2cb)
CGE: 
100757400(Ppp2cb) 100766084(Ppp2ca)
HGL: 
101707511(Ppp2ca) 101726191(Ppp2cb)
TUP: 
102479161(PPP2CA) 102500173(PPP2CB)
CFA: 
403608(PPP2CA) 482873(PPP2CB)
AML: 
FCA: 
101094667(PPP2CB) 101099271(PPP2CA)
PTG: 
102954008(PPP2CA) 102956715(PPP2CB)
BTA: 
282320(PPP2CA) 524361(PPP2CB)
BOM: 
102266065(PPP2CA) 102279886 102282540(PPP2CB)
PHD: 
102326922(PPP2CB) 102337284(PPP2CA)
CHX: 
102175016(PPP2CA) 102182013(PPP2CB) 102189044
SSC: 
397136(PPP2CB) 397656(PPP2CA)
CFR: 
102509650(PPP2CB)
BACU: 
103000342(PPP2CB) 103018989(PPP2CA) 103019215
LVE: 
103074714(PPP2CA) 103086967(PPP2CB)
ECB: 
100062224(PPP2CB) 100072780(PPP2CA)
MYB: 
102246010(PPP2CA) 102255371(PPP2CB)
MYD: 
102762679(PPP2CA) 102771922(PPP2CB)
PALE: 
102885289(PPP2CA) 102887013(PPP2CB)
MDO: 
100012652(PPP2CB) 100017519(PPP2CA)
SHR: 
OAA: 
GGA: 
396021(PPP2CB) 416318(PPP2CA)
MGP: 
TGU: 
FAB: 
101814178(PPP2CA)
PHI: 
APLA: 
101799879(PPP2CB) 101803206(PPP2CA)
FPG: 
FCH: 
102052989(PPP2CB) 102058381(PPP2CA)
CLV: 
ASN: 
AMJ: 
PSS: 
CMY: 
ACS: 
PBI: 
XLA: 
380045(ppp2ca) 399343(ppp2cb)
XTR: 
394888(ppp2ca) 448031(ppp2cb)
DRE: 
393885(Ppp2ca) 406582(ppp2cb) 550585(ppp2ca)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
BFO: 
CIN: 
SPU: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
CQU: 
AME: 
550710(mts)
NVI: 
TCA: 
BMOR: 
API: 
PHU: 
ISC: 
CEL: 
CELE_F38H4.9(let-92)
CBR: 
CBG06179(Cbr-let-92)
BMY: 
LOA: 
TSP: 
SMM: 
NVE: 
HMG: 
TAD: 
AQU: 
ATH: 
AT1G10430(PP2A-2) AT1G59830(PP2A-1) AT1G69960(PP2A) AT2G42500(PP2A-3) AT3G58500(PP2A-4)
ALY: 
CRB: 
EUS: 
CIT: 
CIC: 
TCC: 
GMX: 
PVU: 
MTR: 
CAM: 
FVE: 
PPER: 
CSV: 
RCU: 
POP: 
POPTR_0001s04500g(POPTRDRAFT_547629) POPTR_0003s21320g(POPTRDRAFT_712706) POPTR_0006s21080g(POPTRDRAFT_819327) POPTR_0008s19590g(POPTRDRAFT_657542) POPTR_0010s04890g(POPTRDRAFT_833487) POPTR_0012s07510g(POPTRDRAFT_728788) POPTR_0015s07950g(POPTRDRAFT_824629) POPTR_0016s06190g(POPTRDRAFT_735121)
VVI: 
SLY: 
SOT: 
OSA: 
DOSA: 
Os02t0217600-01(Os02g0217600) Os03t0167700-01(Os03g0167700) Os03t0805300-01(Os03g0805300) Os06t0574500-01(Os06g0574500)
OBR: 
BDI: 
SBI: 
SORBI_01g022230(SORBIDRAFT_01g022230) SORBI_01g046020(SORBIDRAFT_01g046020) SORBI_04g007570(SORBIDRAFT_04g007570) SORBI_10g022710(SORBIDRAFT_10g022710)
ZMA: 
SITA: 
ATR: 
s00133p00104740(AMTR_s00133p00104740) s00146p00037590(AMTR_s00146p00037590)
SMO: 
PPP: 
CRE: 
VCN: 
OLU: 
OTA: 
MIS: 
MPP: 
BPG: 
CSL: 
CVR: 
CME: 
GSL: 
CCP: 
SCE: 
YDL134C(PPH21) YDL188C(PPH22)
AGO: 
ERC: 
KLA: 
LTH: 
PPA: 
VPO: 
ZRO: 
CGR: 
NCS: 
NCAS_0A13850(NCAS0A13850) NCAS_0E03680(NCAS0E03680)
NDI: 
NDAI_0A02190(NDAI0A02190) NDAI_0A02950(NDAI0A02950)
TPF: 
TPHA_0A03180(TPHA0A03180) TPHA_0P00880(TPHA0P00880)
TBL: 
TBLA_0A05910(TBLA0A05910) TBLA_0F02060(TBLA0F02060)
TDL: 
TDEL_0C02450(TDEL0C02450)
KAF: 
KAFR_0B01120(KAFR0B01120)
DHA: 
PIC: 
PGU: 
LEL: 
SPAA: 
CAL: 
CaO19.1683(PPH21) CaO19.9252(PPH21)
CTP: 
CDU: 
COT: 
CTEN: 
YLI: 
CLU: 
NCR: 
SMP: 
PAN: 
TTT: 
MTM: 
CTHR: 
MGR: 
TMN: 
FGR: 
NHE: 
TRE: 
MAW: 
MAJ: 
CMT: 
VAL: 
ELA: 
SSL: 
BFU: 
MBE: 
ANI: 
AFM: 
AOR: 
AOR_1_264194(AO090012000155)
ANG: 
ANI_1_1608104(An12g02970) ANI_1_58094(An11g00420)
AFV: 
ACT: 
NFI: 
PCS: 
CIM: 
CPW: 
PBL: 
URE: 
ABE: 
TVE: 
AJE: 
PNO: 
PTE: 
BZE: 
ZTR: 
PFJ: 
BCOM: 
TML: 
SPO: 
CNE: 
CNB: 
CGI: 
PPL: 
LBC: 
CCI: 
SCM: 
UMA: 
MGL: 
PGR: 
ECU: 
EIN: 
EHE: 
NCE: 
MBR: 
DDI: 
DPP: 
EHI: 
EHI_011950(16.t00005)
EDI: 
ACAN: 
PFA: 
PFD: 
PFH: 
PYO: 
PCB: 
PBE: 
PKN: 
PVX: 
PCY: 
TAN: 
TPV: 
BBO: 
BBOV_I000740(16.m00696)
BEQ: 
CPV: 
CHO: 
TGO: 
TET: 
PTM: 
PTI: 
TPS: 
PIF: 
EHX: 
GTT: 
TBR: 
Tb927.3.1240(Tb03.1J15.680)
TCR: 
LMA: 
LIF: 
LDO: 
LMI: 
LBZ: 
NGR: 
TVA: 
GLA: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Lechward K, Awotunde OS, Swiatek W, Muszynska G
  Title
Protein phosphatase 2A: variety of forms and diversity of functions.
  Journal
Acta Biochim Pol 48:921-33 (2001)
Reference
  Authors
Sontag E
  Title
Protein phosphatase 2A: the Trojan Horse of cellular signaling.
  Journal
Cell Signal 13:7-16 (2001)
Reference
  Authors
Janssens V, Goris J
  Title
Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling.
  Journal
Biochem J 353:417-39 (2001)

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