KEGG   ORTHOLOGY: K04393Help
Entry
K04393                      KO                                     

Name
CDC42
Definition
cell division control protein 42
Pathway
MAPK signaling pathway
MAPK signaling pathway - yeast
Ras signaling pathway
Rap1 signaling pathway
Chemokine signaling pathway
Endocytosis
Axon guidance
VEGF signaling pathway
Focal adhesion
Adherens junction
Tight junction
T cell receptor signaling pathway
Fc gamma R-mediated phagocytosis
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Regulation of actin cytoskeleton
GnRH signaling pathway
Non-alcoholic fatty liver disease (NAFLD)
Bacterial invasion of epithelial cells
Epithelial cell signaling in Helicobacter pylori infection
Pathogenic Escherichia coli infection
Shigellosis
Salmonella infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Renal cell carcinoma
Pancreatic cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K04393  CDC42; cell division control protein 42
   04015 Rap1 signaling pathway
    K04393  CDC42; cell division control protein 42
   04010 MAPK signaling pathway
    K04393  CDC42; cell division control protein 42
   04011 MAPK signaling pathway - yeast
    K04393  CDC42; cell division control protein 42
   04370 VEGF signaling pathway
    K04393  CDC42; cell division control protein 42
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    K04393  CDC42; cell division control protein 42
  Cell motility
   04810 Regulation of actin cytoskeleton
    K04393  CDC42; cell division control protein 42
  Cellular commiunity
   04510 Focal adhesion
    K04393  CDC42; cell division control protein 42
   04520 Adherens junction
    K04393  CDC42; cell division control protein 42
   04530 Tight junction
    K04393  CDC42; cell division control protein 42
 Organismal Systems
  Immune system
   04660 T cell receptor signaling pathway
    K04393  CDC42; cell division control protein 42
   04666 Fc gamma R-mediated phagocytosis
    K04393  CDC42; cell division control protein 42
   04670 Leukocyte transendothelial migration
    K04393  CDC42; cell division control protein 42
   04062 Chemokine signaling pathway
    K04393  CDC42; cell division control protein 42
  Endocrine system
   04912 GnRH signaling pathway
    K04393  CDC42; cell division control protein 42
  Nervous system
   04722 Neurotrophin signaling pathway
    K04393  CDC42; cell division control protein 42
  Development
   04360 Axon guidance
    K04393  CDC42; cell division control protein 42
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K04393  CDC42; cell division control protein 42
   05205 Proteoglycans in cancer
    K04393  CDC42; cell division control protein 42
   05203 Viral carcinogenesis
    K04393  CDC42; cell division control protein 42
   05212 Pancreatic cancer
    K04393  CDC42; cell division control protein 42
   05211 Renal cell carcinoma
    K04393  CDC42; cell division control protein 42
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K04393  CDC42; cell division control protein 42
  Infectious diseases
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K04393  CDC42; cell division control protein 42
   05130 Pathogenic Escherichia coli infection
    K04393  CDC42; cell division control protein 42
   05132 Salmonella infection
    K04393  CDC42; cell division control protein 42
   05131 Shigellosis
    K04393  CDC42; cell division control protein 42
   05100 Bacterial invasion of epithelial cells
    K04393  CDC42; cell division control protein 42
Chromosome [BR:ko03036]
 Eukaryotic Type
  Centrosomal proteins
   Other centrosome associated proteins
    K04393  CDC42; cell division control protein 42
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of microglial cells
   K04393  CDC42; cell division control protein 42
  Exosomal proteins of breast milk
   K04393  CDC42; cell division control protein 42
GTP-binding proteins [BR:ko04031]
 Small (Monomeric) G-proteins
  Rho Family
   Rac/Cdc42 [OT]
    K04393  CDC42; cell division control protein 42
BRITE hierarchy
Genes
HSA: 
998(CDC42)
PTR: 
456609(CDC42) 745248(CDC42)
PPS: 
GGO: 
101124029(CDC42)
PON: 
100438199(CDC42)
MCC: 
707637(CDC42)
MCF: 
MMU: 
12540(Cdc42)
RNO: 
64465(Cdc42)
CGE: 
100765433(Cdc42)
HGL: 
TUP: 
102488344(CDC42)
CFA: 
403934(CDC42)
AML: 
FCA: 
101094772(CDC42)
PTG: 
102973021(CDC42)
BTA: 
532712(CDC42)
BOM: 
102266310(CDC42)
PHD: 
102333527(CDC42)
CHX: 
102188638(CDC42)
OAS: 
101102792(CDC42)
SSC: 
780428(CDC42)
CFR: 
102514486(CDC42)
BACU: 
103008817(CDC42)
LVE: 
103088294(CDC42)
ECB: 
MYB: 
MYD: 
102758165(CDC42)
PALE: 
102889114(CDC42)
MDO: 
100023099(CDC42)
SHR: 
100918370(CDC42)
OAA: 
100086186(CDC42)
GGA: 
395917(CDC42)
MGP: 
TGU: 
100227983(CDC42)
FAB: 
101806194(CDC42)
PHI: 
102106254(CDC42)
APLA: 
101791907(CDC42)
FPG: 
101914879(CDC42)
FCH: 
102055425(CDC42)
CLV: 
102098077(CDC42)
ASN: 
102385507(CDC42)
AMJ: 
102558748(CDC42)
PSS: 
102447391(CDC42)
CMY: 
102931327(CDC42)
PBI: 
103053939(CDC42)
XLA: 
379055(cdc42)
XTR: 
493389(cdc42)
DRE: 
336839(cdc42) 556226(cdc42l2) 793158(cdc42l)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
103181348(cdc42)
BFO: 
CIN: 
445701(cdc42) 445704
SPU: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
CQU: 
AME: 
411134(Cdc42)
NVI: 
TCA: 
BMOR: 
API: 
100145828(Cdc42)
PHU: 
ISC: 
CEL: 
CBR: 
CBG09601(Cbr-crp-1) CBG13013(Cbr-cdc-42)
BMY: 
LOA: 
SMM: 
NVE: 
HMG: 
TAD: 
AQU: 
CCP: 
SCE: 
YLR229C(CDC42)
AGO: 
ERC: 
KLA: 
LTH: 
VPO: 
ZRO: 
CGR: 
NCS: 
NCAS_0B02880(NCAS0B02880)
NDI: 
NDAI_0C04820(NDAI0C04820)
TPF: 
TPHA_0C02190(TPHA0C02190)
TBL: 
TBLA_0H00690(TBLA0H00690) TBLA_0H03330(TBLA0H03330)
TDL: 
TDEL_0F05450(TDEL0F05450)
KAF: 
KAFR_0B06320(KAFR0B06320)
PPA: 
DHA: 
PIC: 
PGU: 
SPAA: 
LEL: 
CAL: 
CaO19.390(CDC42) CaO19.8020(CDC42)
CTP: 
COT: 
CDU: 
CTEN: 
YLI: 
CLU: 
NCR: 
SMP: 
SMAC_02216(cdc42)
PAN: 
TTT: 
MTM: 
CTHR: 
MGR: 
TMN: 
FGR: 
NHE: 
TRE: 
MAW: 
MAJ: 
CMT: 
VAL: 
SSL: 
BFU: 
MBE: 
ANI: 
AFM: 
AOR: 
AOR_1_1240164(AO090001000693)
ANG: 
ANI_1_1958024(An02g14200)
AFV: 
ACT: 
NFI: 
PCS: 
CIM: 
CPW: 
PBL: 
URE: 
ABE: 
TVE: 
PNO: 
PTE: 
BZE: 
BSC: 
BOR: 
ZTR: 
PFJ: 
BCOM: 
NPA: 
SPO: 
SPAC110.03(cdc42)
CNE: 
CNB: 
CGI: 
TMS: 
DSQ: 
SHS: 
PCO: 
PSQ: 
ADL: 
FME: 
GTR: 
LBC: 
MRR: 
CCI: 
SCM: 
ABP: 
AGABI1DRAFT82759(AGABI1DRAFT_82759)
ABV: 
AGABI2DRAFT134270(AGABI2DRAFT_134270)
CPUT: 
SLA: 
UMA: 
PFP: 
MGL: 
MLR: 
WSE: 
ECU: 
EIN: 
NCE: 
MBR: 
NGR: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Takai Y, Sasaki T, Matozaki T.
  Title
Small GTP-binding proteins.
  Journal
Physiol Rev 81:153-208 (2001)
Reference
  Authors
Wennerberg K, Der CJ.
  Title
Rho-family GTPases: it's not only Rac and Rho (and I like it).
  Journal
J Cell Sci 117:1301-12 (2004)

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