KEGG   ORTHOLOGY: K04393Help
Entry
K04393                      KO                                     
Name
CDC42
Definition
cell division control protein 42
Pathway
MAPK signaling pathway
MAPK signaling pathway - yeast
Chemokine signaling pathway
Endocytosis
Axon guidance
VEGF signaling pathway
Focal adhesion
Adherens junction
Tight junction
T cell receptor signaling pathway
Fc gamma R-mediated phagocytosis
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Regulation of actin cytoskeleton
GnRH signaling pathway
Bacterial invasion of epithelial cells
Epithelial cell signaling in Helicobacter pylori infection
Pathogenic Escherichia coli infection
Shigellosis
Salmonella infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Renal cell carcinoma
Pancreatic cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K04393  CDC42; cell division control protein 42
   04011 MAPK signaling pathway - yeast
    K04393  CDC42; cell division control protein 42
   04370 VEGF signaling pathway
    K04393  CDC42; cell division control protein 42
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    K04393  CDC42; cell division control protein 42
  Cell motility
   04810 Regulation of actin cytoskeleton
    K04393  CDC42; cell division control protein 42
  Cell communication
   04510 Focal adhesion
    K04393  CDC42; cell division control protein 42
   04520 Adherens junction
    K04393  CDC42; cell division control protein 42
   04530 Tight junction
    K04393  CDC42; cell division control protein 42
 Organismal Systems
  Immune system
   04660 T cell receptor signaling pathway
    K04393  CDC42; cell division control protein 42
   04666 Fc gamma R-mediated phagocytosis
    K04393  CDC42; cell division control protein 42
   04670 Leukocyte transendothelial migration
    K04393  CDC42; cell division control protein 42
   04062 Chemokine signaling pathway
    K04393  CDC42; cell division control protein 42
  Endocrine system
   04912 GnRH signaling pathway
    K04393  CDC42; cell division control protein 42
  Nervous system
   04722 Neurotrophin signaling pathway
    K04393  CDC42; cell division control protein 42
  Development
   04360 Axon guidance
    K04393  CDC42; cell division control protein 42
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K04393  CDC42; cell division control protein 42
   05205 Proteoglycans in cancer
    K04393  CDC42; cell division control protein 42
   05203 Viral carcinogenesis
    K04393  CDC42; cell division control protein 42
   05212 Pancreatic cancer
    K04393  CDC42; cell division control protein 42
   05211 Renal cell carcinoma
    K04393  CDC42; cell division control protein 42
  Infectious diseases
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K04393  CDC42; cell division control protein 42
   05130 Pathogenic Escherichia coli infection
    K04393  CDC42; cell division control protein 42
   05132 Salmonella infection
    K04393  CDC42; cell division control protein 42
   05131 Shigellosis
    K04393  CDC42; cell division control protein 42
   05100 Bacterial invasion of epithelial cells
    K04393  CDC42; cell division control protein 42
Chromosome [BR:ko03036]
 Eukaryotic Type
  Centrosomal proteins
   Other centrosome associated proteins
    K04393  CDC42; cell division control protein 42
GTP-binding proteins [BR:ko04031]
 Small (Monomeric) G-proteins
  Rho Family
   Rac/Cdc42
    K04393  CDC42; cell division control protein 42
BRITE hierarchy
Genes
HSA: 
998(CDC42)
PTR: 
456609(CDC42) 745248
PPS: 
GGO: 
101124029(CDC42)
PON: 
100438199(CDC42)
MCC: 
707637(CDC42)
MMU: 
12540(Cdc42)
RNO: 
64465(Cdc42)
CFA: 
403934(CDC42)
AML: 
FCA: 
101094772(CDC42)
BTA: 
532712(CDC42)
SSC: 
780428(CDC42)
ECB: 
100051322 100058188
MDO: 
100009767 100012700 100023099
SHR: 
100918370(CDC42)
OAA: 
100086186
GGA: 
395917(CDC42)
MGP: 
100546318
TGU: 
100227983(CDC42)
XLA: 
379055(cdc42)
XTR: 
493389(cdc42)
DRE: 
336839(cdc42) 556226(cdc42l2) 793158(cdc42l)
TRU: 
101067723 101068145
OLA: 
101164400 101164658 101172972
BFO: 
BRAFLDRAFT_111365 BRAFLDRAFT_122664 BRAFLDRAFT_88994
CIN: 
445701(cdc42) 445704
SPU: 
584477
DME: 
Dmel_CG12530(Cdc42)
DPO: 
Dpse_GA11680
DAN: 
Dana_GF20423
DER: 
Dere_GG19248
DPE: 
Dper_GL18265
DSE: 
Dsec_GM22983
DSI: 
Dsim_GD17456
DWI: 
Dwil_GK17312
DYA: 
Dyak_GE15867
DGR: 
Dgri_GH12491
DMO: 
Dmoj_GI11109
DVI: 
Dvir_GJ15962
AGA: 
AgaP_AGAP002440(CDC42_ANOGA) AgaP_AGAP006279
AAG: 
AaeL_AAEL008543 AaeL_AAEL011500
CQU: 
CpipJ_CPIJ009514 CpipJ_CPIJ014902
AME: 
411134(Cdc42)
NVI: 
100115209(NV18192) 100116519(NV17867)
TCA: 
657937
API: 
100145828(Cdc42)
PHU: 
Phum_PHUM424410
ISC: 
IscW_ISCW003614
CEL: 
CELE_R07G3.1(cdc-42) CELE_Y32F6B.3(crp-1)
CBR: 
CBG09601(Cbr-crp-1) CBG13013(Cbr-cdc-42)
BMY: 
Bm1_42715 Bm1_55955
SMM: 
Smp_082810.1 Smp_082810.2
NVE: 
NEMVE_v1g17158 NEMVE_v1g189251
HMG: 
100204156
TAD: 
TRIADDRAFT_50431
AQU: 
100636735
SCE: 
YLR229C(CDC42)
AGO: 
AGOS_AGL093W
ERC: 
Ecym_4146
KLA: 
KLLA0A04213g
LTH: 
KLTH0F07920g
PPA: 
PAS_chr2-1_0112
VPO: 
Kpol_529p16
ZRO: 
ZYRO0A09306g
CGR: 
CAGL0F05269g
NCS: 
NCAS_0B02880(NCAS0B02880)
NDI: 
NDAI_0C04820(NDAI0C04820)
TPF: 
TPHA_0C02190(TPHA0C02190)
TBL: 
TBLA_0H03330(TBLA0H03330)
TDL: 
TDEL_0F05450(TDEL0F05450)
KAF: 
KAFR_0B06320(KAFR0B06320)
DHA: 
DEHA2G14168g
PIC: 
PICST_35277(CDC42)
PGU: 
PGUG_04396
LEL: 
LELG_00656
CAL: 
CaO19.390(CDC42) CaO19.8020(CDC42)
CTP: 
CTRG_03158
CDU: 
CD36_07960
COT: 
CORT_0A06630
YLI: 
YALI0B15752g
CLU: 
CLUG_03902
NCR: 
NCU06454
SMP: 
SMAC_02216(cdc42)
PAN: 
PODANSg5389
TTT: 
THITE_2155778
MTM: 
MYCTH_2303801
MGR: 
MGG_00466
FGR: 
FG05447.1
NHE: 
NECHADRAFT_71164
SSL: 
SS1G_13726
BFU: 
BC1G_15519
ANI: 
AN7487.2
NFI: 
NFIA_082460
AFM: 
AFUA_2G05740
AOR: 
AOR_1_1240164(AO090001000693)
ANG: 
ANI_1_1958024(An02g14200)
AFV: 
AFLA_129910
ACT: 
ACLA_068600
PCS: 
Pc22g09010
CIM: 
CIMG_00786
CPW: 
CPC735_055160
PBL: 
PAAG_02230
URE: 
UREG_00754
ABE: 
ARB_03852
PNO: 
SNOG_12991
PTE: 
PTT_09197
ZTR: 
MYCGRDRAFT_99553(MgCdc42)
SPO: 
SPAC110.03(cdc42)
CNE: 
CNF00160 CNH00140
CNB: 
CNBF4550 CNBL0140
CGI: 
CGB_F6460W CGB_H0200C
LBC: 
LACBIDRAFT_172912
CCI: 
CC1G_10838
SCM: 
SCHCODRAFT_84650
UMA: 
UM00295.1
MGL: 
MGL_0548
ECU: 
ECU03_1560
EIN: 
Eint_031480
NCE: 
NCER_100146
MBR: 
MONBRDRAFT_33406
TVA: 
TVAG_169060
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Takai Y, Sasaki T, Matozaki T.
  Title
Small GTP-binding proteins.
  Journal
Physiol Rev 81:153-208 (2001)
Reference
  Authors
Wennerberg K, Der CJ.
  Title
Rho-family GTPases: it's not only Rac and Rho (and I like it).
  Journal
J Cell Sci 117:1301-12 (2004)
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