KEGG   ORTHOLOGY: K04402Help
Entry
K04402                      KO                                     

Name
GADD45
Definition
growth arrest and DNA-damage-inducible protein
Pathway
MAPK signaling pathway
FoxO signaling pathway
Cell cycle
p53 signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K04402  GADD45; growth arrest and DNA-damage-inducible protein
   04068 FoxO signaling pathway
    K04402  GADD45; growth arrest and DNA-damage-inducible protein
 Cellular Processes
  Cell growth and death
   04110 Cell cycle
    K04402  GADD45; growth arrest and DNA-damage-inducible protein
   04115 p53 signaling pathway
    K04402  GADD45; growth arrest and DNA-damage-inducible protein
Chromosome [BR:ko03036]
 Eukaryotic Type
  Centrosomal proteins
   Centrosome duplication proteins
    Other centrosome duplication proteins
     K04402  GADD45; growth arrest and DNA-damage-inducible protein
  Sister chromatid separation proteins
   Aurora kinases
    Regulators of Aurora kinases
     K04402  GADD45; growth arrest and DNA-damage-inducible protein
BRITE hierarchy
Genes
HSA: 
10912(GADD45G) 1647(GADD45A) 4616(GADD45B)
PTR: 
456929(GADD45A) 464585(GADD45G) 744311(GADD45B)
PPS: 
100982764(GADD45B) 100990548(GADD45A) 100992917(GADD45G)
GGO: 
101131508 101140270(GADD45B) 101146783(GADD45A)
PON: 
100436665 100452809(GADD45B) 100456437(GADD45A)
MCC: 
697835(GADD45G) 701054(GADD45A) 711257(GADD45B)
MCF: 
102115080(GADD45B) 102128083(GADD45A) 102135480(GADD45G)
MMU: 
13197(Gadd45a) 17873(Gadd45b) 23882(Gadd45g)
RNO: 
25112(Gadd45a) 291005(Gadd45g) 299626(Gadd45b)
CGE: 
100759228(Gadd45g) 100766127(Gadd45b) 103159266
HGL: 
101710909(Gadd45b) 101711314 101725746(Gadd45a)
TUP: 
102476523(GADD45B) 102496861(GADD45G) 102502813(GADD45A)
CFA: 
100855728(GADD45A) 484198(GADD45G) 485069(GADD45B)
AML: 
FCA: 
101086509(GADD45G) 101087971(GADD45B)
PTG: 
102951885(GADD45A) 102964763(GADD45B)
BTA: 
504939(GADD45G) 505463(GADD45A) 618405(GADD45B)
BOM: 
102266978(GADD45B) 102276116 102288000(GADD45A)
PHD: 
102324661(GADD45B) 102341257(GADD45A) 102343412(GADD45G)
CHX: 
102179904(GADD45A) 102183684(GADD45B) 102188317(GADD45G)
OAS: 
100885762(GADD45G) 101115240(GADD45A) 101120573(GADD45B)
SSC: 
100152997(GADD45G) 100621090(GADD45B) 733669(GADD45A)
CFR: 
102508482(GADD45A) 102516207(GADD45B)
BACU: 
103012188(GADD45G) 103016967(GADD45B) 103020367(GADD45A)
LVE: 
103079241(GADD45G) 103080866(GADD45A) 103089793(GADD45B)
ECB: 
100054996(GADD45G) 100059768(GADD45B) 100630299(GADD45A)
MYB: 
102239140(GADD45B) 102242156(GADD45A) 102246302(GADD45G)
MYD: 
102751752(GADD45B) 102752386(GADD45A) 102771581(GADD45G)
PALE: 
102878191(GADD45G) 102885790(GADD45B) 102886440(GADD45A)
MDO: 
100010225 100014651(GADD45B) 100016952(GADD45A)
SHR: 
OAA: 
100081893(GADD45A) 100090762(GADD45B)
GGA: 
100859853 429929(GADD45B) 693255(GADD45A)
MGP: 
TGU: 
FAB: 
PHI: 
102102492(GADD45A) 102109500(GADD45G) 102109553(GADD45B)
APLA: 
FPG: 
101915163(GADD45G) 101916621(GADD45B)
FCH: 
102057224(GADD45G) 102057932(GADD45B)
CLV: 
102084445(GADD45A) 102087532(GADD45B) 102090065(GADD45G)
ASN: 
102372381(GADD45G) 102374172(GADD45A) 102374205(GADD45B)
AMJ: 
102560377 102570271(GADD45B) 102575022(GADD45A)
PSS: 
102447859(GADD45G) 102457123(GADD45A) 102460773
CMY: 
102935322(GADD45A) 102943336(GADD45G) 102945688(GADD45B)
ACS: 
100554443(gadd45a) 100567812(gadd45g)
PBI: 
103059109(GADD45A) 103063697 103064821(GADD45G)
XLA: 
101027271 379224(gadd45a) 379285 399196(gadd45g)
XTR: 
100487013(gadd45b) 448442(gadd45g) 548905(gadd45a)
DRE: 
393548(gadd45aa) 402991(gadd45g) 406304(gadd45ba) 431763(gadd45ab) 497646(gadd45bb)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102349018(GADD45A) 102353479 102361538(GADD45B)
CMK: 
103181960(gadd45b) 103182857(gadd45g) 103189132(gadd45a)
SPU: 
DME: 
Dmel_CG11086(Gadd45)
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
CQU: 
TCA: 
BMOR: 
NVE: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Papa S, Zazzeroni F, Bubici C, Jayawardena S, Alvarez K, Matsuda S, Nguyen DU, Pham CG, Nelsbach AH, Melis T, De Smaele E, Tang WJ, D'Adamio L, Franzoso G
  Title
Gadd45 beta mediates the NF-kappa B suppression of JNK signalling by targeting MKK7/JNKK2.
  Journal
Nat Cell Biol 6:146-53 (2004)
Reference
  Authors
Wang X, Wang RH, Li W, Xu X, Hollander MC, Fornace AJ Jr, Deng CX
  Title
Genetic interactions between Brca1 and Gadd45a in centrosome duplication, genetic stability, and neural tube closure.
  Journal
J Biol Chem 279:29606-14 (2004)
Reference
  Authors
Shao S, Wang Y, Jin S, Song Y, Wang X, Fan W, Zhao Z, Fu M, Tong T, Dong L, Fan F, Xu N, Zhan Q
  Title
Gadd45a interacts with aurora-A and inhibits its kinase activity.
  Journal
J Biol Chem 281:28943-50 (2006)

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