KEGG   ORTHOLOGY: K04415Help
Entry
K04415                      KO                                     

Name
MAP3K8, COT
Definition
mitogen-activated protein kinase kinase kinase 8 [EC:2.7.11.25]
Pathway
MAPK signaling pathway
Toll-like receptor signaling pathway
T cell receptor signaling pathway
TNF signaling pathway
Module
M00688  
MAPK (JNK) signaling
M00689  
MAPK (p38) signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K04415  MAP3K8, COT; mitogen-activated protein kinase kinase kinase 8
   04668 TNF signaling pathway
    K04415  MAP3K8, COT; mitogen-activated protein kinase kinase kinase 8
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    K04415  MAP3K8, COT; mitogen-activated protein kinase kinase kinase 8
   04660 T cell receptor signaling pathway
    K04415  MAP3K8, COT; mitogen-activated protein kinase kinase kinase 8
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00688  MAPK (JNK) signaling
     K04415  MAP3K8, COT; mitogen-activated protein kinase kinase kinase 8
    M00689  MAPK (p38) signaling
     K04415  MAP3K8, COT; mitogen-activated protein kinase kinase kinase 8
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.25  mitogen-activated protein kinase kinase kinase
     K04415  MAP3K8, COT; mitogen-activated protein kinase kinase kinase 8
Protein kinases [BR:ko01001]
 Serine/threonine protein kinases: STE group
  Other families
   K04415  MAP3K8, COT; mitogen-activated protein kinase kinase kinase 8
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
1326(MAP3K8)
PTR: 
450384(MAP3K8)
PPS: 
100978161(MAP3K8)
GGO: 
101133328(MAP3K8)
PON: 
100434157(MAP3K8)
NLE: 
100579516(MAP3K8)
MCC: 
696936(MAP3K8)
MCF: 
CSAB: 
103247459(MAP3K8)
RRO: 
104657273(MAP3K8)
RBB: 
108528065(MAP3K8)
CJC: 
100385107(MAP3K8)
SBQ: 
101046566(MAP3K8)
MMU: 
26410(Map3k8)
RNO: 
116596(Map3k8)
CGE: 
100759538(Map3k8)
NGI: 
103747991(Map3k8)
HGL: 
101710286(Map3k8)
CCAN: 
109695913(Map3k8)
OCU: 
100355566(MAP3K8)
TUP: 
102493021(MAP3K8)
CFA: 
487085(MAP3K8)
AML: 
100480593(MAP3K8)
UMR: 
103656496(MAP3K8)
FCA: 
101090624(MAP3K8)
PTG: 
102961042(MAP3K8)
AJU: 
106977317(MAP3K8)
BTA: 
535622(MAP3K8)
BOM: 
102278856(MAP3K8)
BIU: 
109568007(MAP3K8)
PHD: 
102329999(MAP3K8)
CHX: 
102188512(MAP3K8)
OAS: 
101117094(MAP3K8)
SSC: 
100622217(MAP3K8)
CFR: 
102518335(MAP3K8)
CDK: 
105096296(MAP3K8)
BACU: 
103010611(MAP3K8)
LVE: 
103070441(MAP3K8)
ECB: 
100063602(MAP3K8)
EPZ: 
103541518(MAP3K8)
EAI: 
106837968(MAP3K8)
MYB: 
102248363(MAP3K8)
MYD: 
102775461(MAP3K8)
HAI: 
109389111(MAP3K8)
RSS: 
109447311(MAP3K8)
PALE: 
102896654(MAP3K8)
LAV: 
100662383(MAP3K8)
MDO: 
100018684(MAP3K8)
SHR: 
100925633(MAP3K8)
OAA: 
100076215(MAP3K8)
GGA: 
420479(MAP3K8)
MGP: 
100541097(MAP3K8)
CJO: 
107308936(MAP3K8)
APLA: 
101791769(MAP3K8)
ACYG: 
106042681(MAP3K8)
TGU: 
100230596(MAP3K8)
GFR: 
102035976(MAP3K8)
FAB: 
101819414(MAP3K8)
PHI: 
102114163(MAP3K8)
PMAJ: 
107200816(MAP3K8)
CCW: 
104686470(MAP3K8)
FPG: 
101921040(MAP3K8)
FCH: 
102055830(MAP3K8)
CLV: 
102087091(MAP3K8)
AAM: 
106489958(MAP3K8)
ASN: 
102387437(MAP3K8)
AMJ: 
102566471(MAP3K8)
PSS: 
102449623(MAP3K8)
CMY: 
102936511(MAP3K8)
CPIC: 
101941097(MAP3K8)
ACS: 
100562883(map3k8)
PVT: 
110082918(MAP3K8)
PBI: 
103064348(MAP3K8)
GJA: 
107107910(MAP3K8)
XLA: 
108718772(map3k8.L) 108719849(map3k8.S)
XTR: 
100493069(map3k8)
NPR: 
108788845(MAP3K8)
DRE: 
563727(map3k8)
SRX: 
SANH: 
SGH: 
IPU: 
108274187(map3k8)
AMEX: 
103031259(map3k8)
TRU: 
101069247(map3k8)
TNG: 
LCO: 
104928818(map3k8)
NCC: 
104953904(map3k8)
MZE: 
101484222(map3k8)
OLA: 
101159779(map3k8)
XMA: 
102235260(map3k8)
CSEM: 
103376862(map3k8)
LCF: 
HCQ: 
109514181(map3k8)
SASA: 
ELS: 
105019416(map3k8)
SFM: 
LCM: 
102367513(MAP3K8)
CMK: 
103186428(map3k8)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Craig EA, Stevens MV, Vaillancourt RR, Camenisch TD
  Title
MAP3Ks as central regulators of cell fate during development.
  Journal
Dev Dyn 237:3102-14 (2008)
DOI:10.1002/dvdy.21750

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