KEGG   ORTHOLOGY: K04428Help
Entry
K04428                      KO                                     

Name
MAP3K4, MEKK4
Definition
mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25]
Pathway
MAPK signaling pathway
MAPK signaling pathway - fly
GnRH signaling pathway
Module
M00688  
MAPK (JNK) signaling
M00689  
MAPK (p38) signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K04428  MAP3K4, MEKK4; mitogen-activated protein kinase kinase kinase 4
   04013 MAPK signaling pathway - fly
    K04428  MAP3K4, MEKK4; mitogen-activated protein kinase kinase kinase 4
 Organismal Systems
  Endocrine system
   04912 GnRH signaling pathway
    K04428  MAP3K4, MEKK4; mitogen-activated protein kinase kinase kinase 4
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00688  MAPK (JNK) signaling
     K04428  MAP3K4, MEKK4; mitogen-activated protein kinase kinase kinase 4
    M00689  MAPK (p38) signaling
     K04428  MAP3K4, MEKK4; mitogen-activated protein kinase kinase kinase 4
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.25  mitogen-activated protein kinase kinase kinase
     K04428  MAP3K4, MEKK4; mitogen-activated protein kinase kinase kinase 4
Protein kinases [BR:ko01001]
 Serine/threonine protein kinases: STE group
  STE11 family
   K04428  MAP3K4, MEKK4; mitogen-activated protein kinase kinase kinase 4
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
4216(MAP3K4)
PTR: 
463119(MAP3K4)
PPS: 
100981441(MAP3K4)
GGO: 
101152649(MAP3K4)
PON: 
100442172(MAP3K4)
NLE: 
100602313(MAP3K4)
MCC: 
710360(MAP3K4)
MCF: 
101865276(MAP3K4)
RRO: 
104669999(MAP3K4)
CJC: 
100413660(MAP3K4)
MMU: 
26407(Map3k4)
RNO: 
308106(Map3k4)
CGE: 
100764060(Map3k4)
NGI: 
103737023(Map3k4)
HGL: 
101701961(Map3k4)
OCU: 
100358104(MAP3K4)
TUP: 
102479582(MAP3K4)
CFA: 
476262(MAP3K4)
AML: 
100465667(MAP3K4)
UMR: 
103660898(MAP3K4)
FCA: 
101097977(MAP3K4)
PTG: 
102952700(MAP3K4)
BTA: 
511779(MAP3K4)
BOM: 
102283969(MAP3K4)
PHD: 
102328534(MAP3K4)
CHX: 
102172543(MAP3K4)
OAS: 
101113246(MAP3K4)
SSC: 
100154202(MAP3K4) 100518455(MAP3K4)
CFR: 
102509815(MAP3K4)
BACU: 
103006512(MAP3K4)
LVE: 
103075844(MAP3K4)
ECB: 
100058153(MAP3K4)
MYB: 
102262729(MAP3K4)
MYD: 
102757393(MAP3K4)
PALE: 
102888506(MAP3K4)
MDO: 
100032495(MAP3K4)
SHR: 
100928208(MAP3K4)
OAA: 
GGA: 
421579(MAP3K4)
MGP: 
100548383(MAP3K4)
CJO: 
107311515(MAP3K4)
APLA: 
101795899(MAP3K4)
TGU: 
100229845(MAP3K4)
GFR: 
102043718(MAP3K4)
FAB: 
101814940(MAP3K4)
PHI: 
102101107(MAP3K4)
CCW: 
104684463(MAP3K4)
FPG: 
101918017(MAP3K4)
FCH: 
102048037(MAP3K4)
CLV: 
102086486(MAP3K4)
AAM: 
106486799(MAP3K4)
ASN: 
102382136(MAP3K4)
AMJ: 
102573918(MAP3K4)
PSS: 
102446659(MAP3K4)
CMY: 
102936228(MAP3K4)
ACS: 
100560027(map3k4)
PBI: 
103059578(MAP3K4)
GJA: 
107113333(MAP3K4)
XTR: 
100497217(map3k4)
DRE: 
325488(map3k4)
TRU: 
101076799(map3k4)
MZE: 
101485830(map3k4)
OLA: 
101174856(map3k4)
XMA: 
102230475(map3k4)
LCM: 
102366133(MAP3K4)
CMK: 
103175928(map3k4)
CIN: 
778975(mapkkk4)
SPU: 
SKO: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
Dsimw501_GD20154(Dsim_GD20154)
DWI: 
DYA: 
Dyak_GE25175(dyak_GLEANR_8804)
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
CQU: 
AME: 
409125(Mekk1)
SOC: 
AEC: 
HST: 
CFO: 
NVI: 
TCA: 
BMOR: 
PXY: 
API: 
CEL: 
CBR: 
CBG04061(Cbr-mtk-1)
BMY: 
LOA: 
HRO: 
LGI: 
CRG: 
OBI: 
TAD: 
AQU: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9079650
  Authors
Gerwins P, Blank JL, Johnson GL
  Title
Cloning of a novel mitogen-activated protein kinase kinase kinase, MEKK4, that selectively regulates the c-Jun amino terminal kinase pathway.
  Journal
J Biol Chem 272:8288-95 (1997)
  Sequence
[mmu:26407]

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