KEGG   ORTHOLOGY: K04432Help
Entry
K04432                      KO                                     

Name
MAP2K3, MKK3
Definition
mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
Pathway
MAPK signaling pathway
MAPK signaling pathway - fly
Rap1 signaling pathway
Toll-like receptor signaling pathway
Toll and Imd signaling pathway
Fc epsilon RI signaling pathway
TNF signaling pathway
Inflammatory mediator regulation of TRP channels
GnRH signaling pathway
Amyotrophic lateral sclerosis (ALS)
Toxoplasmosis
Influenza A
Epstein-Barr virus infection
Module
M00689  
MAPK (p38) signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3
   04010 MAPK signaling pathway
    K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3
   04013 MAPK signaling pathway - fly
    K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3
   04668 TNF signaling pathway
    K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3
   04624 Toll and Imd signaling pathway
    K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3
   04664 Fc epsilon RI signaling pathway
    K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3
  Endocrine system
   04912 GnRH signaling pathway
    K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3
 Human Diseases
  Neurodegenerative diseases
   05014 Amyotrophic lateral sclerosis (ALS)
    K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3
  Infectious diseases
   05164 Influenza A
    K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3
   05169 Epstein-Barr virus infection
    K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3
   05145 Toxoplasmosis
    K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00689  MAPK (p38) signaling
     K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3
Protein kinases [BR:ko01001]
 Serine/threonine protein kinases: STE group
  STE7 family
   K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
5606(MAP2K3)
PTR: 
454515(MAP2K3)
PPS: 
100975020(MAP2K3)
GGO: 
101145420(MAP2K3)
PON: 
100457536(MAP2K3)
NLE: 
100588703(MAP2K3)
MCC: 
705195(MAP2K3)
MCF: 
102116823(MAP2K3)
CSAB: 
103242535(MAP2K3)
RRO: 
104678467(MAP2K3)
CJC: 
100398593(MAP2K3)
SBQ: 
101034633(MAP2K3)
MMU: 
26397(Map2k3)
RNO: 
CGE: 
100756793(Map2k3)
NGI: 
103724822(Map2k3)
HGL: 
101718318(Map2k3)
OCU: 
100339953(MAP2K3)
TUP: 
102499419(MAP2K3)
CFA: 
489547(MAP2K3)
AML: 
100476678(MAP2K3)
UMR: 
103658475(MAP2K3)
FCA: 
101082274(MAP2K3)
PTG: 
102949954(MAP2K3)
BTA: 
516039(MAP2K3)
BOM: 
102267773(MAP2K3)
PHD: 
102315849(MAP2K3)
CHX: 
102173967(MAP2K3)
OAS: 
101122959(MAP2K3)
CFR: 
102523780(MAP2K3)
BACU: 
103019100(MAP2K3)
LVE: 
103091611(MAP2K3)
ECB: 
100053481(MAP2K3)
MYB: 
102259712(MAP2K3)
MYD: 
102765923(MAP2K3)
PALE: 
102886389(MAP2K3)
LAV: 
100675607(MAP2K3)
MDO: 
100016872(MAP2K3)
SHR: 
100925586(MAP2K3)
OAA: 
100080734(MAP2K3)
GGA: 
416496(MAP2K3)
MGP: 
100542290(MAP2K3)
CJO: 
107320760(MAP2K3)
APLA: 
101803371(MAP2K3)
TGU: 
100229860(MAP2K3)
GFR: 
102039295(MAP2K3)
FAB: 
101809415(MAP2K3)
PHI: 
102109535(MAP2K3)
CCW: 
104684789(MAP2K3)
FPG: 
101919170(MAP2K3)
FCH: 
102052703(MAP2K3)
CLV: 
102085143(MAP2K3)
AAM: 
ASN: 
102383945(MAP2K3)
AMJ: 
102566638(MAP2K3)
PSS: 
102454019(MAP2K3)
CMY: 
102939584(MAP2K3)
ACS: 
100561588(map2k3)
PBI: 
103065723(MAP2K3)
GJA: 
LCM: 
102351267(MAP2K3)
CMK: 
SKO: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
Dyak_GE17041(dyak_GLEANR_18406)
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
CQU: 
AME: 
725374(GB16739)
BIM: 
SOC: 
AEC: 
HST: 
CFO: 
NVI: 
TCA: 
BMOR: 
DPL: 
PXY: 
API: 
PHU: 
DPX: 
ISC: 
TSP: 
HRO: 
LGI: 
OBI: 
TAD: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8900184
  Authors
Moriguchi T, Toyoshima F, Gotoh Y, Iwamatsu A, Irie K, Mori E, Kuroyanagi N, Hagiwara M, Matsumoto K, Nishida E
  Title
Purification and identification of a major activator for p38 from osmotically shocked cells. Activation of mitogen-activated protein kinase kinase 6 by osmotic shock, tumor necrosis factor-alpha, and H2O2.
  Journal
J Biol Chem 271:26981-8 (1996)
  Sequence
[hsa:5606] [mmu:26397]
Reference
PMID:8622669
  Authors
Raingeaud J, Whitmarsh AJ, Barrett T, Derijard B, Davis RJ
  Title
MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway.
  Journal
Mol Cell Biol 16:1247-55 (1996)
  Sequence
[hsa:5606]

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