KEGG   ORTHOLOGY: K04445Help
Entry
K04445                      KO                                     

Name
MSK1, RPS6KA5
Definition
ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
Pathway
MAPK signaling pathway
Adrenergic signaling in cardiomyocytes
TNF signaling pathway
Circadian entrainment
Neurotrophin signaling pathway
MicroRNAs in cancer
Bladder cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K04445  MSK1, RPS6KA5; ribosomal protein S6 kinase alpha-5
   04668 TNF signaling pathway
    K04445  MSK1, RPS6KA5; ribosomal protein S6 kinase alpha-5
 Organismal Systems
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K04445  MSK1, RPS6KA5; ribosomal protein S6 kinase alpha-5
  Nervous system
   04722 Neurotrophin signaling pathway
    K04445  MSK1, RPS6KA5; ribosomal protein S6 kinase alpha-5
  Environmental adaptation
   04713 Circadian entrainment
    K04445  MSK1, RPS6KA5; ribosomal protein S6 kinase alpha-5
 Human Diseases
  Cancers
   05206 MicroRNAs in cancer
    K04445  MSK1, RPS6KA5; ribosomal protein S6 kinase alpha-5
   05219 Bladder cancer
    K04445  MSK1, RPS6KA5; ribosomal protein S6 kinase alpha-5
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K04445  MSK1, RPS6KA5; ribosomal protein S6 kinase alpha-5
Protein kinases [BR:ko01001]
 Serine/threonine protein kinases: AGC group
  RSK family [OT]
   K04445  MSK1, RPS6KA5; ribosomal protein S6 kinase alpha-5
BRITE hierarchy
Genes
HSA: 
9252(RPS6KA5)
PTR: 
739162(RPS6KA5)
PPS: 
100971222(RPS6KA5)
GGO: 
101152851(RPS6KA5)
PON: 
100173967(RPS6KA5)
MCC: 
699798(RPS6KA5)
MCF: 
102137672(RPS6KA5)
MMU: 
73086(Rps6ka5)
RNO: 
314384(Rps6ka5)
CGE: 
100753249(Rps6ka5)
HGL: 
101712306(Rps6ka5)
TUP: 
102486242(RPS6KA5)
CFA: 
490831(RPS6KA5)
AML: 
FCA: 
101095179(RPS6KA5)
PTG: 
102952316(RPS6KA5)
BTA: 
504408(RPS6KA5)
BOM: 
102283727(RPS6KA5)
PHD: 
102329968(RPS6KA5)
CHX: 
102191054(RPS6KA5)
SSC: 
100152046(RPS6KA5)
CFR: 
102512204(RPS6KA5)
BACU: 
102999918(RPS6KA5)
LVE: 
103080020(RPS6KA5)
ECB: 
100062953(RPS6KA5)
MYB: 
102252210(RPS6KA5)
MYD: 
102754112(RPS6KA5)
PALE: 
102897813(RPS6KA5)
MDO: 
100017874(RPS6KA5) 100031342(RPS6KA4)
SHR: 
100931885(RPS6KA5)
OAA: 
100075221(RPS6KA5)
GGA: 
423408(RPS6KA5)
MGP: 
TGU: 
100219984(RPS6KA5)
FAB: 
101818385(RPS6KA5)
PHI: 
102108626(RPS6KA5)
APLA: 
101790699(RPS6KA5)
FPG: 
101919264(RPS6KA5)
FCH: 
102049415(RPS6KA5)
CLV: 
102089255(RPS6KA5)
ASN: 
102381351(RPS6KA5)
AMJ: 
102576860(RPS6KA5)
PSS: 
102463390(RPS6KA5)
CMY: 
102931440(RPS6KA5)
ACS: 
PBI: 
XTR: 
100489041(rps6ka5)
DRE: 
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
BFO: 
CIN: 
100175922(rps6ka5)
SPU: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
AME: 
411630(JIL-1)
NVI: 
TCA: 
BMOR: 
PHU: 
ISC: 
CEL: 
CELE_C54G4.1(rskn-2)
CBR: 
CBG08209(Cbr-rskn-2)
BMY: 
LOA: 
NVE: 
HMG: 
TAD: 
AQU: 
MBR: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Soloaga A, Thomson S, Wiggin GR, Rampersaud N, Dyson MH, Hazzalin CA, Mahadevan LC, Arthur JS
  Title
MSK2 and MSK1 mediate the mitogen- and stress-induced phosphorylation of histone  H3 and HMG-14.
  Journal
EMBO J 22:2788-97 (2003)

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