KEGG   ORTHOLOGY: K04448Help
Entry
K04448                      KO                                     

Name
JUN
Definition
transcription factor AP-1
Pathway
MAPK signaling pathway
ErbB signaling pathway
cAMP signaling pathway
Wnt signaling pathway
Osteoclast differentiation
Focal adhesion
Toll-like receptor signaling pathway
T cell receptor signaling pathway
B cell receptor signaling pathway
TNF signaling pathway
Neurotrophin signaling pathway
GnRH signaling pathway
Estrogen signaling pathway
Oxytocin signaling pathway
Non-alcoholic fatty liver disease (NAFLD)
Cocaine addiction
Amphetamine addiction
Epithelial cell signaling in Helicobacter pylori infection
Salmonella infection
Pertussis
Leishmaniasis
Chagas disease (American trypanosomiasis)
Hepatitis B
Influenza A
HTLV-I infection
Herpes simplex infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Colorectal cancer
Renal cell carcinoma
Inflammatory bowel disease (IBD)
Rheumatoid arthritis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K04448  JUN; transcription factor AP-1
   04012 ErbB signaling pathway
    K04448  JUN; transcription factor AP-1
   04310 Wnt signaling pathway
    K04448  JUN; transcription factor AP-1
   04668 TNF signaling pathway
    K04448  JUN; transcription factor AP-1
   04024 cAMP signaling pathway
    K04448  JUN; transcription factor AP-1
 Cellular Processes
  Cellular commiunity
   04510 Focal adhesion
    K04448  JUN; transcription factor AP-1
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    K04448  JUN; transcription factor AP-1
   04660 T cell receptor signaling pathway
    K04448  JUN; transcription factor AP-1
   04662 B cell receptor signaling pathway
    K04448  JUN; transcription factor AP-1
  Endocrine system
   04912 GnRH signaling pathway
    K04448  JUN; transcription factor AP-1
   04915 Estrogen signaling pathway
    K04448  JUN; transcription factor AP-1
   04921 Oxytocin signaling pathway
    K04448  JUN; transcription factor AP-1
  Nervous system
   04722 Neurotrophin signaling pathway
    K04448  JUN; transcription factor AP-1
  Development
   04380 Osteoclast differentiation
    K04448  JUN; transcription factor AP-1
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K04448  JUN; transcription factor AP-1
   05203 Viral carcinogenesis
    K04448  JUN; transcription factor AP-1
   05210 Colorectal cancer
    K04448  JUN; transcription factor AP-1
   05211 Renal cell carcinoma
    K04448  JUN; transcription factor AP-1
  Immune diseases
   05323 Rheumatoid arthritis
    K04448  JUN; transcription factor AP-1
   05321 Inflammatiory bowel disease (IBD)
    K04448  JUN; transcription factor AP-1
  Substance dependence
   05030 Cocaine addiction
    K04448  JUN; transcription factor AP-1
   05031 Amphetamine addiction
    K04448  JUN; transcription factor AP-1
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K04448  JUN; transcription factor AP-1
  Infectious diseases
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K04448  JUN; transcription factor AP-1
   05132 Salmonella infection
    K04448  JUN; transcription factor AP-1
   05133 Pertussis
    K04448  JUN; transcription factor AP-1
   05166 HTLV-I infection
    K04448  JUN; transcription factor AP-1
   05164 Influenza A
    K04448  JUN; transcription factor AP-1
   05161 Hepatitis B
    K04448  JUN; transcription factor AP-1
   05168 Herpes simplex infection
    K04448  JUN; transcription factor AP-1
   05169 Epstein-Barr virus infection
    K04448  JUN; transcription factor AP-1
   05140 Leishmaniasis
    K04448  JUN; transcription factor AP-1
   05142 Chagas disease (American trypanosomiasis)
    K04448  JUN; transcription factor AP-1
Transcription factors [BR:ko03000]
 Eukaryotic Type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, Jun
    K04448  JUN; transcription factor AP-1
BRITE hierarchy
Genes
HSA: 
3725(JUN)
PTR: 
456893(JUN)
PPS: 
GGO: 
PON: 
MCC: 
716452(JUN)
MCF: 
MMU: 
16476(Jun)
RNO: 
24516(Jun)
CGE: 
HGL: 
TUP: 
CFA: 
609429(JUN)
AML: 
FCA: 
PTG: 
BTA: 
280831(JUN)
BOM: 
PHD: 
CHX: 
SSC: 
396913(C-JUN)
BACU: 
LVE: 
ECB: 
MYB: 
MYD: 
PALE: 
MDO: 
GGA: 
424673(JUN)
MGP: 
TGU: 
FAB: 
PHI: 
APLA: 
FPG: 
FCH: 
CLV: 
ASN: 
AMJ: 
PSS: 
CMY: 
ACS: 
PBI: 
XLA: 
379050(jun) 399400(jun)
XTR: 
DRE: 
335916(jun)
TRU: 
101064806(c-junl) 101077059(c-jun)
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
BFO: 
CIN: 
778972(jun)
SPU: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
CQU: 
AME: 
726289(Jra)
NVI: 
TCA: 
663937(Jra)
BMOR: 
API: 
PHU: 
ISC: 
BMY: 
TSP: 
NVE: 
HMG: 
TAD: 
AQU: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Eferl R, Wagner EF
  Title
AP-1: a double-edged sword in tumorigenesis.
  Journal
Nat Rev Cancer 3:859-68 (2003)
Reference
  Authors
Shaulian E, Karin M
  Title
AP-1 as a regulator of cell life and death.
  Journal
Nat Cell Biol 4:E131-6 (2002)

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