KEGG   ORTHOLOGY: K04452Help
Entry
K04452                      KO                                     

Name
DDIT3, GADD153
Definition
DNA damage-inducible transcript 3
Pathway
MAPK signaling pathway
Protein processing in endoplasmic reticulum
Non-alcoholic fatty liver disease (NAFLD)
Transcriptional misregulation in cancer
Disease
H00049  
Myxoid liposarcoma
Brite
KEGG Orthology (KO) [BR:ko00001]
 Genetic Information Processing
  Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    K04452  DDIT3, GADD153; DNA damage-inducible transcript 3
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K04452  DDIT3, GADD153; DNA damage-inducible transcript 3
 Human Diseases
  Cancers
   05202 Transcriptional misregulation in cancers
    K04452  DDIT3, GADD153; DNA damage-inducible transcript 3
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K04452  DDIT3, GADD153; DNA damage-inducible transcript 3
Transcription factors [BR:ko03000]
 Eukaryotic Type
  Basic leucine zipper (bZIP)
   C/EBP-like factors
    K04452  DDIT3, GADD153; DNA damage-inducible transcript 3
BRITE hierarchy
Genes
HSA: 
1649(DDIT3)
PTR: 
452017(DDIT3)
PPS: 
100982590(DDIT3)
GGO: 
101140706(DDIT3)
PON: 
100439399(DDIT3)
MCC: 
714901(DDIT3)
MCF: 
102131632(DDIT3)
MMU: 
13198(Ddit3)
RNO: 
29467(Ddit3)
CGE: 
100763514(Ddit3)
HGL: 
101715873(Ddit3)
TUP: 
102500216(DDIT3)
CFA: 
607439(DDIT3)
AML: 
FCA: 
101081819(DDIT3)
PTG: 
102965918(DDIT3)
BTA: 
777788(DDIT3)
BOM: 
102284065(DDIT3)
PHD: 
102322887(DDIT3)
CHX: 
102175557(DDIT3)
OAS: 
541600(DDIT3)
SSC: 
100240743(DDIT3)
CFR: 
102517621(DDIT3)
BACU: 
103018481(DDIT3)
LVE: 
103069139(DDIT3)
ECB: 
100053417(DDIT3)
MYB: 
102255226(DDIT3)
MYD: 
102764039(DDIT3)
PALE: 
102890557(DDIT3)
SHR: 
100931338(DDIT3)
GGA: 
100857832(DDIT3)
PHI: 
102105586(DDIT3)
APLA: 
101802390(DDIT3)
FPG: 
101914191(DDIT3)
ASN: 
102384643(DDIT3)
AMJ: 
102574043(DDIT3)
PSS: 
CMY: 
102934528(DDIT3)
ACS: 
100567470(ddit3)
PBI: 
103050195(DDIT3)
XLA: 
398615(ddit3)
XTR: 
733816(ddit3)
LCM: 
102361121(DDIT3)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Oyadomari S, Mori M
  Title
Roles of CHOP/GADD153 in endoplasmic reticulum stress.
  Journal
Cell Death Differ 11:381-9 (2004)
Reference
  Authors
Perez-Mancera PA, Sanchez-Garcia I
  Title
Understanding mesenchymal cancer: the liposarcoma-associated FUS-DDIT3 fusion gene as a model.
  Journal
Semin Cancer Biol 15:206-14 (2005)

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