KEGG   ORTHOLOGY: K04457Help
Entry
K04457                      KO                                     

Name
PPM1A, PP2CA
Definition
protein phosphatase 1A [EC:3.1.3.16]
Pathway
MAPK signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K04457  PPM1A, PP2CA; protein phosphatase 1A
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     K04457  PPM1A, PP2CA; protein phosphatase 1A
Protein phosphatases and associated proteins [BR:ko01009]
 Protein Ser/ Thr phosphatases
  Mg2+- or Mn2+- dependent protein phosphatases (PPMs)
   PPM1 phosphatases (PP2C)
    K04457  PPM1A, PP2CA; protein phosphatase 1A
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
5494(PPM1A)
PTR: 
452950(PPM1A)
PPS: 
100970419(PPM1A)
GGO: 
101125419(PPM1A)
PON: 
100173950(PPM1A)
NLE: 
100582171(PPM1A)
MCC: 
702987(PPM1A)
MCF: 
102124885(PPM1A)
CJC: 
100405518(PPM1A)
MMU: 
19042(Ppm1a)
RNO: 
24666(Ppm1a)
CGE: 
100773654(Ppm1a)
NGI: 
103739185(Ppm1a)
HGL: 
101720711(Ppm1a)
OCU: 
100009431(PPM1A)
TUP: 
102486395(PPM1A)
CFA: 
480344(PPM1A)
AML: 
UMR: 
103672639(PPM1A)
FCA: 
101101571(PPM1A)
PTG: 
102953651(PPM1A)
BTA: 
281994(PPM1A)
BOM: 
102285226(PPM1A)
PHD: 
102334333(PPM1A)
CHX: 
102177529(PPM1A)
OAS: 
101103650(PPM1A)
SSC: 
100738389(PPM1A)
CFR: 
102511888(PPM1A)
BACU: 
103004855(PPM1A)
LVE: 
103087588(PPM1A)
ECB: 
100051348(PPM1A)
MYB: 
102249748(PPM1A)
MYD: 
102754169(PPM1A)
PALE: 
102894756(PPM1A)
MDO: 
100021641(PPM1A)
SHR: 
100918256(PPM1A)
OAA: 
100086309(PPM1A)
GGA: 
423525(PPM1A)
MGP: 
100544655(PPM1A)
APLA: 
101799571(PPM1A)
TGU: 
100225828(PPM1A)
FAB: 
101807578(PPM1A)
PHI: 
102113668(PPM1A)
CCW: 
104687344(PPM1A)
FPG: 
101917369(PPM1A)
FCH: 
102058428(PPM1A)
CLV: 
102089447(PPM1A)
ASN: 
102367870(PPM1A)
AMJ: 
102572447(PPM1A)
PSS: 
102460132(PPM1A)
CMY: 
102943068(PPM1A)
ACS: 
PBI: 
103060451(PPM1A)
XLA: 
380058(ppm1a)
XTR: 
548912(ppm1a)
DRE: 
30703(ppm1ab) 30704(ppm1aa) 405817(ppm1na) 564875(ppm1nb)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102351446(PPM1A)
CMK: 
103185375(ppm1a)
CIN: 
SMM: 
HMG: 
OSA: 
AFM: 
PCS: 
PTM: 
TPS: 
LMA: 
LIF: 
LDO: 
LMI: 
LBZ: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Lin X, Duan X, Liang YY, Su Y, Wrighton KH, Long J, Hu M, Davis CM, Wang J, Brunicardi FC, Shi Y, Chen YG, Meng A, Feng XH
  Title
PPM1A functions as a Smad phosphatase to terminate TGFbeta signaling.
  Journal
Cell 125:915-28 (2006)
  Sequence
[hsa:5494]
Reference
  Authors
Sun W, Yu Y, Dotti G, Shen T, Tan X, Savoldo B, Pass AK, Chu M, Zhang D, Lu X, Fu S, Lin X, Yang J
  Title
PPM1A and PPM1B act as IKKbeta phosphatases to terminate TNFalpha-induced IKKbeta-NF-kappaB activation.
  Journal
Cell Signal 21:95-102 (2009)
  Sequence
[hsa:5494]

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