KEGG   ORTHOLOGY: K04519Help
Entry
K04519                      KO                                     

Name
IL1B
Definition
interleukin 1 beta
Pathway
MAPK signaling pathway
Cytokine-cytokine receptor interaction
NF-kappa B signaling pathway
Apoptosis
Osteoclast differentiation
Toll-like receptor signaling pathway
NOD-like receptor signaling pathway
Cytosolic DNA-sensing pathway
Hematopoietic cell lineage
TNF signaling pathway
Inflammatory mediator regulation of TRP channels
Non-alcoholic fatty liver disease (NAFLD)
Type I diabetes mellitus
Alzheimer's disease
Prion diseases
Salmonella infection
Pertussis
Legionellosis
Leishmaniasis
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Malaria
Amoebiasis
Tuberculosis
Measles
Influenza A
Herpes simplex infection
Inflammatory bowel disease (IBD)
Rheumatoid arthritis
Graft-versus-host disease
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K04519  IL1B; interleukin 1 beta
   04064 NF-kappa B signaling pathway
    K04519  IL1B; interleukin 1 beta
   04668 TNF signaling pathway
    K04519  IL1B; interleukin 1 beta
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K04519  IL1B; interleukin 1 beta
 Cellular Processes
  Cell growth and death
   04210 Apoptosis
    K04519  IL1B; interleukin 1 beta
 Organismal Systems
  Immune system
   04640 Hematopoietic cell lineage
    K04519  IL1B; interleukin 1 beta
   04620 Toll-like receptor signaling pathway
    K04519  IL1B; interleukin 1 beta
   04621 NOD-like receptor signaling pathway
    K04519  IL1B; interleukin 1 beta
   04623 Cytosolic DNA-sensing pathway
    K04519  IL1B; interleukin 1 beta
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K04519  IL1B; interleukin 1 beta
  Development
   04380 Osteoclast differentiation
    K04519  IL1B; interleukin 1 beta
 Human Diseases
  Immune diseases
   05323 Rheumatoid arthritis
    K04519  IL1B; interleukin 1 beta
   05321 Inflammatiory bowel disease (IBD)
    K04519  IL1B; interleukin 1 beta
   05332 Graft-versus-host disease
    K04519  IL1B; interleukin 1 beta
  Neurodegenerative diseases
   05010 Alzheimer's disease
    K04519  IL1B; interleukin 1 beta
   05020 Prion diseases
    K04519  IL1B; interleukin 1 beta
  Endocrine and metabolic diseases
   04940 Type I diabetes mellitus
    K04519  IL1B; interleukin 1 beta
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K04519  IL1B; interleukin 1 beta
  Infectious diseases
   05132 Salmonella infection
    K04519  IL1B; interleukin 1 beta
   05133 Pertussis
    K04519  IL1B; interleukin 1 beta
   05134 Legionellosis
    K04519  IL1B; interleukin 1 beta
   05152 Tuberculosis
    K04519  IL1B; interleukin 1 beta
   05162 Measles
    K04519  IL1B; interleukin 1 beta
   05164 Influenza A
    K04519  IL1B; interleukin 1 beta
   05168 Herpes simplex infection
    K04519  IL1B; interleukin 1 beta
   05146 Amoebiasis
    K04519  IL1B; interleukin 1 beta
   05144 Malaria
    K04519  IL1B; interleukin 1 beta
   05140 Leishmaniasis
    K04519  IL1B; interleukin 1 beta
   05142 Chagas disease (American trypanosomiasis)
    K04519  IL1B; interleukin 1 beta
   05143 African trypanosomiasis
    K04519  IL1B; interleukin 1 beta
Cytokines [BR:ko04052]
 IL-1 family
  K04519  IL1B; interleukin 1 beta
Heparan sulfate/heparin binding proteins [BR:ko00536]
 Cytokines
  K04519  IL1B; interleukin 1 beta
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
3553(IL1B)
PTR: 
450200(IL1B)
PPS: 
100993613(IL1B)
GGO: 
101130571(IL1B)
PON: 
100454379(IL1B)
NLE: 
100587357(IL1B)
MCC: 
704701(IL1B)
MCF: 
102119749(IL1B)
CJC: 
100406769(IL1B)
MMU: 
16176(Il1b)
RNO: 
24494(Il1b)
CGE: 
100775079(Il1b)
NGI: 
103739899(Il1b)
HGL: 
101704309(Il1b)
OCU: 
100008990(IL1B)
TUP: 
102475138(IL1B)
CFA: 
403974(IL1B)
AML: 
UMR: 
103671495(IL1B)
FCA: 
768274(IL1B)
PTG: 
102951272(IL1B)
BTA: 
281251(IL1B)
BOM: 
102282890(IL1B)
PHD: 
102329073(IL1B)
CHX: 
100860816(IL1B)
OAS: 
443539(IL-1B)
SSC: 
396565(IL1B2) 397122(IL1B1)
CFR: 
102521979(IL1B)
BACU: 
103008438(IL1B)
LVE: 
103090784(IL1B)
ECB: 
MYB: 
102251576(IL1B)
MYD: 
102769803(IL1B)
PALE: 
102893238(IL1B)
MDO: 
100026024(IL1B)
SHR: 
100922350(IL1B)
OAA: 
103165286(IL1B)
GGA: 
395196(IL1B)
MGP: 
100034741(IL1B)
TGU: 
FAB: 
101819115(IL1B)
PHI: 
102108659(IL1B)
FPG: 
FCH: 
102050776(IL1B)
CLV: 
102090585(IL1B)
ASN: 
102369595(IL1B)
AMJ: 
PSS: 
102448244(IL1B)
CMY: 
PBI: 
XLA: 
373606(il1b)
XTR: 
100487038(il1b)
DRE: 
405770(il1b)
TRU: 
101080001(il-1beta)
MZE: 
OLA: 
LCM: 
CMK: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Sims JE, Smith DE
  Title
The IL-1 family: regulators of immunity.
  Journal
Nat Rev Immunol 10:89-102 (2010)

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