KEGG   ORTHOLOGY: K04526Help
Entry
K04526                      KO                                     

Name
INS
Definition
insulin
Pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Oocyte meiosis
Regulation of autophagy
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Regulation of actin cytoskeleton
Insulin signaling pathway
Insulin secretion
Ovarian steroidogenesis
Progesterone-mediated oocyte maturation
Prolactin signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Type I diabetes mellitus
Maturity onset diabetes of the young
Aldosterone-regulated sodium reabsorption
Prostate cancer
Disease
H00408  
Type I diabetes mellitus
H00410  
Maturity onset diabetes of the young (MODY)
H00512  
Permanent neonatal diabetes mellitus (PNDM)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K04526  INS; insulin
   04015 Rap1 signaling pathway
    K04526  INS; insulin
   04066 HIF-1 signaling pathway
    K04526  INS; insulin
   04068 FoxO signaling pathway
    K04526  INS; insulin
   04022 cGMP - PKG signaling pathway
    K04526  INS; insulin
   04151 PI3K-Akt signaling pathway
    K04526  INS; insulin
   04152 AMPK signaling pathway
    K04526  INS; insulin
   04150 mTOR signaling pathway
    K04526  INS; insulin
 Cellular Processes
  Transport and catabolism
   04140 Regulation of autophagy
    K04526  INS; insulin
  Cell motility
   04810 Regulation of actin cytoskeleton
    K04526  INS; insulin
  Cell growth and death
   04114 Oocyte meiosis
    K04526  INS; insulin
 Organismal Systems
  Endocrine system
   04911 Insulin secretion
    K04526  INS; insulin
   04910 Insulin signaling pathway
    K04526  INS; insulin
   04913 Ovarian Steroidogenesis
    K04526  INS; insulin
   04914 Progesterone-mediated oocyte maturation
    K04526  INS; insulin
   04917 Prolactin signaling pathway
    K04526  INS; insulin
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    K04526  INS; insulin
 Human Diseases
  Cancers
   05215 Prostate cancer
    K04526  INS; insulin
  Endocrine and metabolic diseases
   04940 Type I diabetes mellitus
    K04526  INS; insulin
   04930 Type II diabetes mellitus
    K04526  INS; insulin
   04950 Maturity onset diabetes of the young
    K04526  INS; insulin
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K04526  INS; insulin
BRITE hierarchy
Genes
HSA: 
3630(INS)
PTR: 
449570(INS)
GGO: 
PON: 
MCF: 
MMU: 
16333(Ins1) 16334(Ins2)
RNO: 
24505(Ins1) 24506(Ins2)
CGE: 
HGL: 
TUP: 
CFA: 
483665(INS)
AML: 
FCA: 
493804(INS)
BTA: 
280829(INS)
BOM: 
SSC: 
397415(INS)
BACU: 
LVE: 
ECB: 
MYB: 
MYD: 
PALE: 
GGA: 
396145(INS)
MGP: 
TGU: 
FAB: 
PHI: 
APLA: 
FPG: 
FCH: 
CLV: 
ASN: 
AMJ: 
PSS: 
CMY: 
ACS: 
PBI: 
XLA: 
378695(ins-b) 378696(ins-a)
XTR: 
DRE: 
30262(ins) 566735(insb)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
DAN: 
DGR: 
DMO: 
DVI: 
TCA: 
BMOR: 
100169708(Bbx-a7) 100653512(BmILP)
API: 
ISC: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Lizcano JM, Alessi DR
  Title
The insulin signalling pathway.
  Journal
Curr Biol 12:R236-8 (2002)

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