KEGG   ORTHOLOGY: K04534Help
Entry
K04534                      KO                                     

Name
GNAO, G-ALPHA-O
Definition
guanine nucleotide-binding protein G(o) subunit alpha
Pathway
Rap1 signaling pathway
Circadian entrainment
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
GABAergic synapse
Dopaminergic synapse
Long-term depression
Estrogen signaling pathway
Melanogenesis
Oxytocin signaling pathway
Relaxin signaling pathway
Morphine addiction
Alcoholism
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Disease
H00606  
Early infantile epileptic encephalopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
 Organismal Systems
  Endocrine system
   04915 Estrogen signaling pathway
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
   04921 Oxytocin signaling pathway
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
   04926 Relaxin signaling pathway
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
   04916 Melanogenesis
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
  Nervous system
   04724 Glutamatergic synapse
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
   04727 GABAergic synapse
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
   04725 Cholinergic synapse
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
   04728 Dopaminergic synapse
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
   04726 Serotonergic synapse
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
   04730 Long-term depression
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
   04723 Retrograde endocannabinoid signaling
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
  Environmental adaptation
   04713 Circadian entrainment
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
 Human Diseases
  Substance dependence
   05032 Morphine addiction
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
   05034 Alcoholism
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
  Infectious diseases
   05145 Toxoplasmosis
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
   05142 Chagas disease (American trypanosomiasis)
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
GTP-binding proteins [BR:ko04031]
 Heterotrimeric G-proteins
  Alpha Subunits
   Alpha type 1 (Gi/o) [OT]
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
BRITE hierarchy
Genes
HSA: 
2775(GNAO1)
PTR: 
450173(GNAO1)
PPS: 
100991540(GNAO1)
GGO: 
101150695(GNAO1)
PON: 
100454626(GNAO1)
NLE: 
MCC: 
574394(GNAO1)
MCF: 
102131761(GNAO1)
CSAB: 
103233012(GNAO1)
RRO: 
RBB: 
108533839(GNAO1)
CJC: 
100389396(GNAO1) 103789429(GNAO1)
SBQ: 
101049046(GNAO1)
MMU: 
14681(Gnao1)
RNO: 
50664(Gnao1)
CGE: 
100689069(Gnao1)
NGI: 
103749858(Gnao1)
HGL: 
101723580(Gnao1)
CCAN: 
109700326(Gnao1)
OCU: 
100342283(GNAO1)
TUP: 
102483059(GNAO1)
CFA: 
609157(GNAO1)
AML: 
100466130(GNAO1)
UMR: 
FCA: 
101101353(GNAO1)
PTG: 
102958483(GNAO1)
AJU: 
BTA: 
281792(GNAO1)
BOM: 
102280695(GNAO1)
BIU: 
109572786(GNAO1)
PHD: 
102320226(GNAO1)
CHX: 
102186145(GNAO1)
OAS: 
101119495(GNAO1)
SSC: 
100516976(GNAO1)
CFR: 
CDK: 
105096168(GNAO1)
BACU: 
103011674(GNAO1)
LVE: 
103091025(GNAO1)
ECB: 
100051282(GNAO1)
EPZ: 
103555391(GNAO1)
EAI: 
106822188(GNAO1)
MYB: 
102263380(GNAO1)
MYD: 
102765603(GNAO1)
HAI: 
RSS: 
109459434(GNAO1)
PALE: 
102884654(GNAO1)
LAV: 
100658419(GNAO1)
MDO: 
100015137(GNAO1)
SHR: 
100914773(GNAO1)
OAA: 
100074566(GNAO1)
GGA: 
415698(GNAO1)
MGP: 
100543011(GNAO1)
CJO: 
107319187(GNAO1)
APLA: 
ACYG: 
106043102(GNAO1)
TGU: 
100226617(GNAO1)
GFR: 
102040380(GNAO1)
FAB: 
101810253(GNAO1)
PHI: 
102101605(GNAO1)
PMAJ: 
107209802(GNAO1)
CCW: 
104687499(GNAO1)
FPG: 
101920934(GNAO1)
FCH: 
102052678(GNAO1)
CLV: 
102098346(GNAO1)
AAM: 
106496793(GNAO1)
ASN: 
102370246(GNAO1)
AMJ: 
102575346(GNAO1)
PSS: 
102448010(GNAO1)
CMY: 
102938723(GNAO1)
CPIC: 
101939865(GNAO1)
ACS: 
PVT: 
110085725(GNAO1)
PBI: 
GJA: 
107118988(GNAO1)
XLA: 
108714022 394423(gnao1.L) 397896(gna0) 398037
XTR: 
549749(gnao1)
NPR: 
108793915(GNAO1)
DRE: 
393760(gnao1a) 393801(gnao1b)
SRX: 
SANH: 
SGH: 
IPU: 
AMEX: 
103039135(gnao1)
TRU: 
101079681(gnao1)
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
108918980(gnao1)
LCM: 
102363494(GNAO1)
CMK: 
BFO: 
SPU: 
SKO: 
DME: 
Dmel_CG2204(Galphao)
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
Dsimw501_GD10742(Dsim_GD10742)
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
CQU: 
AME: 
BIM: 
BTER: 
SOC: 
AEC: 
ACEP: 
PBAR: 
HST: 
CFO: 
LHU: 
PGC: 
NVI: 
100118592(Gnao)
TCA: 
DPA: 
NVL: 
BMOR: 
692460(Go)
DPL: 
PXY: 
API: 
100168757(Gnao1)
DNX: 
PHU: 
FCD: 
DPX: 
ISC: 
TUT: 
CEL: 
CBR: 
CBG08377(Cbr-gpa-7) CBG11277(Cbr-gpa-2) CBG19263(Cbr-gpa-3) CBG23127(Cbr-gpa-1) CBG24698(Cbr-goa-1)
NAI: 
BMY: 
LOA: 
TSP: 
HRO: 
LGI: 
CRG: 
OBI: 
LAK: 
SMM: 
SHX: 
OVI: 
NVE: 
ADF: 
HMG: 
MBR: 
SRE: 
DPP: 
ACAN: 
PTI: 
FCY: 
TPS: 
AAF: 
PIF: 
PSOJ: 
NGR: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1901650
  Authors
Tsukamoto T, Toyama R, Itoh H, Kozasa T, Matsuoka M, Kaziro Y
  Title
Structure of the human gene and two rat cDNAs encoding the alpha chain of GTP-binding regulatory protein Go: two different mRNAs are generated by alternative splicing.
  Journal
Proc Natl Acad Sci U S A 88:2974-8 (1991)
  Sequence
[hsa:2775]

DBGET integrated database retrieval system