KEGG ORTHOLOGY: K04534

ORTHOLOGY: K04534

Entry

K04534 KO

Name

GNAO, G-ALPHA-O

Definition

guanine nucleotide-binding protein G(o) subunit alpha

Pathway

ko04713	Circadian entrainment
ko04723	Retrograde endocannabinoid signaling
ko04724	Glutamatergic synapse
ko04725	Cholinergic synapse
ko04726	Serotonergic synapse
ko04727	GABAergic synapse
ko04728	Dopaminergic synapse
ko04730	Long-term depression
ko04915	Estrogen signaling pathway
ko04916	Melanogenesis
ko05032	Morphine addiction
ko05034	Alcoholism
ko05142	Chagas disease (American trypanosomiasis)
ko05145	Toxoplasmosis

Brite

KEGG Orthology (KO) [BR:ko00001]
Organismal Systems
  Endocrine system
   04915 Estrogen signaling pathway
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
   04916 Melanogenesis
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
  Nervous system
   04724 Glutamatergic synapse
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
   04727 GABAergic synapse
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
   04725 Cholinergic synapse
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
   04728 Dopaminergic synapse
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
   04726 Serotonergic synapse
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
   04730 Long-term depression
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
   04723 Retrograde endocannabinoid signaling
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
  Environmental adaptation
   04713 Circadian entrainment
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
Human Diseases
  Substance dependence
   05032 Morphine addiction
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
   05034 Alcoholism
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
  Infectious diseases
   05145 Toxoplasmosis
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
   05142 Chagas disease (American trypanosomiasis)
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
GTP-binding proteins [BR:ko04031]
Heterotrimeric G-proteins
  Alpha Subunits
   Alpha type 1 (Gi)
    K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha

Genes

HSA:	2775(GNAO1)
PTR:	450173(GNAO1)
PPS:	100991540(GNAO1)
GGO:	101150695
PON:	100454626(GNAO1)
MCC:	574394(GNAO1)
MMU:	14681(Gnao1)
RNO:	50664(Gnao1)
CFA:	609157(GNAO1)
AML:	100466130(GNAO1)
FCA:	101101353(GNAO1)
BTA:	281792(GNAO1)
SSC:	100516976
ECB:	100051282(GNAO1)
MDO:	100015137(GNAO1)
SHR:	100914773(GNAO1)
OAA:	100074566
GGA:	415698(GNAO1)
MGP:	100543011
TGU:	100226617(GNAO1)
ACS:	100561396
XLA:	394423(gnao1) 397896(gna0) 398037
XTR:	549749(gnao1)
DRE:	393760(gnao1a) 393801(gnao1b)
TRU:	101079681
OLA:	101166207
BFO:	BRAFLDRAFT_77291
SPU:	576911
DME:	Dmel_CG2204(G-oalpha47A)
DPO:	Dpse_GA15300
DAN:	Dana_GF13765
DER:	Dere_GG24169
DPE:	Dper_GL17293
DSE:	Dsec_GM21219
DSI:	Dsim_GD10742
DWI:	Dwil_GK17798
DYA:	Dyak_GE19363
DGR:	Dgri_GH21256
DMO:	Dmoj_GI19334
DVI:	Dvir_GJ22212
AGA:	AgaP_AGAP005773
AAG:	AaeL_AAEL008641
CQU:	CpipJ_CPIJ000066
NVI:	100118592(Gnao)
TCA:	655023
API:	100168757(Gnao1)
PHU:	Phum_PHUM378990
ISC:	IscW_ISCW017464
CEL:	CELE_C26C6.2(goa-1)
CBR:	CBG24698(Cbr-goa-1)
TSP:	Tsp_10201
SMM:	Smp_016630.1
NVE:	NEMVE_v1g237532
MBR:	MONBRDRAFT_37969

» show all

Reference

PMID:16402120

Authors

Milligan G, Kostenis E

Title

Heterotrimeric G-proteins: a short history.

Journal

Br J Pharmacol 147 Suppl 1:S46-55 (2006)

Reference

PMID:16183910

Authors

Wettschureck N, Offermanns S.

Title

Mammalian G proteins and their cell type specific functions.

Journal

Physiol Rev 85:1159-204 (2005)

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (28)   
   KEGG PATHWAY (28)   
Gene (109)   
   KEGG GENES (57)   
   KEGG DGENES (5)   
   KEGG EGENES (44)   
   KEGG MGENES (3)   
Protein sequence (49)   
   UniProt (49)   
Literature (2)   
   PubMed (2)   
All databases (190)   

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