KEGG   ORTHOLOGY: K04604Help
Entry
K04604                      KO                                     

Name
GRM5
Definition
metabotropic glutamate receptor 5
Pathway
ko04020  Calcium signaling pathway
ko04072  Phospholipase D signaling pathway
ko04080  Neuroactive ligand-receptor interaction
ko04540  Gap junction
ko04720  Long-term potentiation
ko04723  Retrograde endocannabinoid signaling
ko04724  Glutamatergic synapse
ko05016  Huntington's disease
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04020 Calcium signaling pathway
    K04604  GRM5; metabotropic glutamate receptor 5
   04072 Phospholipase D signaling pathway
    K04604  GRM5; metabotropic glutamate receptor 5
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04604  GRM5; metabotropic glutamate receptor 5
 Cellular Processes
  Cellular community - eukaryotes
   04540 Gap junction
    K04604  GRM5; metabotropic glutamate receptor 5
 Organismal Systems
  Nervous system
   04724 Glutamatergic synapse
    K04604  GRM5; metabotropic glutamate receptor 5
   04720 Long-term potentiation
    K04604  GRM5; metabotropic glutamate receptor 5
   04723 Retrograde endocannabinoid signaling
    K04604  GRM5; metabotropic glutamate receptor 5
 Human Diseases
  Neurodegenerative diseases
   05016 Huntington's disease
    K04604  GRM5; metabotropic glutamate receptor 5
G protein-coupled receptors [BR:ko04030]
 Class C. Metabotropic glutamate receptor family
  Biogenic amine
   Glutamate (metabotropic) [OT]
    K04604  GRM5; metabotropic glutamate receptor 5
BRITE hierarchy
Other DBs
GO: 0001639
Genes
HSA: 2915(GRM5)
PTR: 451472(GRM5)
PPS: 100988134(GRM5)
GGO: 101148125(GRM5)
PON: 100452002(GRM5)
NLE: 100595085(GRM5)
MCC: 705445(GRM5)
MCF: 101926080(GRM5)
CSAB: 103248193(GRM5)
RRO: 104657433(GRM5)
RBB: 108539155(GRM5)
CJC: 100400074(GRM5)
SBQ: 101043023(GRM5) 104652498
MMU: 108071(Grm5)
RNO: 24418(Grm5)
CGE: 100763614(Grm5)
NGI: 103742957(Grm5)
HGL: 101696979(Grm5)
CCAN: 109674757
OCU: 100340633(GRM5)
TUP: 102486954(GRM5)
CFA: 485146(GRM5)
AML: 100466868(GRM5)
UMR: 103675379(GRM5)
ORO: 101364945(GRM5) 101372426
FCA: 101091895(GRM5)
PTG: 102957191(GRM5)
AJU: 106967780(GRM5)
BTA: 100336861(GRM5)
BOM: 102273282(GRM5)
BIU: 109554000(GRM5)
PHD: 102331335(GRM5)
CHX: 102182568(GRM5)
OAS: 443069(GRM5)
SSC: 102161751(GRM5)
CFR: 102510039(GRM5)
CDK: 105098361(GRM5)
BACU: 103017209(GRM5)
LVE: 103089884(GRM5)
OOR: 101280226(GRM5)
ECB: 100060364(GRM5)
EPZ: 103547854(GRM5)
EAI: 106822674 106848216(GRM5)
MYB: 102243205(GRM5) 102261422
MYD: 102763091(GRM5)
HAI: 109375479(GRM5)
RSS: 109451409(GRM5)
PALE: 102894122(GRM5)
LAV: 100676641(GRM5)
TMU: 101340926
MDO: 100009917(GRM5)
SHR: 100913241(GRM5)
OAA: 100080549(GRM5)
GGA: 373933(GRM5)
CJO: 107308455(GRM5)
APLA: 101805339(GRM5) 106018480
ACYG: 106034184(GRM5)
TGU: 752008(GRM5)
GFR: 102035609(GRM5)
FAB: 101814322(GRM5)
PHI: 102104616(GRM5)
PMAJ: 107207537(GRM5)
CCW: 104690322(GRM5)
FPG: 101915830(GRM5)
FCH: 102054087(GRM5)
CLV: 102093525(GRM5)
EGZ: 104128833(GRM5)
AAM: 106482085(GRM5)
ASN: 102385450(GRM5)
AMJ: 102576482(GRM5)
PSS: 102454127(GRM5)
CMY: 102935827(GRM5)
CPIC: 101935299(GRM5)
ACS: 100563209(grm5)
PVT: 110088579(GRM5)
PBI: 103056145(GRM5) 103060240
GJA: 107113358(GRM5)
XTR: 100485273(grm5)
NPR: 108794764(GRM5)
DRE: 100332913(grm5b) 568406(grm5a)
IPU: 108277301(grm5) 108277953
TRU: 101064551(grm5) 101079916
LCO: 104920135(grm5) 104923830
NCC: 104959637 104963006(grm5)
OLA: 101164491(grm5) 101173805
XMA: 102230735 102230987(grm5)
PRET: 103474487(grm5) 103475526
NFU: 107380453(grm5) 107386961
LCF: 108886623(grm5) 108893271
HCQ: 109509731 109525514(grm5)
BPEC: 110158381 110174304(grm5)
ELS: 105024084(grm5) 105026648
SFM: 108923808 108932228(grm5)
LCM: 102352410 102366420(GRM5)
CMK: 103184347(grm5)
TCA: 657397
NVL: 108556944
CEL: CELE_F45H11.4(mgl-2)
CBR: CBG02196(Cbr-mgl-2)
BMY: Bm1_13620
TSP: Tsp_11217
MYI: 110446254
EPA: 110245306
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Niswender CM, Conn PJ
  Title
Metabotropic glutamate receptors: physiology, pharmacology, and disease.
  Journal
Annu Rev Pharmacol Toxicol 50:295-322 (2010)
DOI:10.1146/annurev.pharmtox.011008.145533
Reference
  Authors
Pin JP, Galvez T, Prezeau L
  Title
Evolution, structure, and activation mechanism of family 3/C G-protein-coupled receptors.
  Journal
Pharmacol Ther 98:325-54 (2003)
DOI:10.1016/S0163-7258(03)00038-X
Reference
  Authors
Xiao XL, Ma DL, Wu J, Tang FR
  Title
Metabotropic glutamate receptor 5 (mGluR5) regulates proliferation and differentiation of neuronal progenitors in the developmental hippocampus.
  Journal
Brain Res 1493:1-12 (2013)
DOI:10.1016/j.brainres.2012.11.015
  Sequence
[mmu:108071]

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