| Entry |
|
| Name |
GRM5
|
| Definition |
metabotropic glutamate receptor 5
|
| Pathway |
| Calcium signaling pathway | | Neuroactive ligand-receptor interaction | | Gap junction | | Long-term potentiation | | Retrograde endocannabinoid signaling | | Glutamatergic synapse | | Huntington's disease |
|
| Brite |
KEGG Orthology (KO) [BR:ko00001]
Environmental Information Processing
Signal transduction
04020 Calcium signaling pathway
K04604 GRM5; metabotropic glutamate receptor 5
Signaling molecules and interaction
04080 Neuroactive ligand-receptor interaction
K04604 GRM5; metabotropic glutamate receptor 5
Cellular Processes
Cell communication
04540 Gap junction
K04604 GRM5; metabotropic glutamate receptor 5
Organismal Systems
Nervous system
04724 Glutamatergic synapse
K04604 GRM5; metabotropic glutamate receptor 5
04720 Long-term potentiation
K04604 GRM5; metabotropic glutamate receptor 5
04723 Retrograde endocannabinoid signaling
K04604 GRM5; metabotropic glutamate receptor 5
Human Diseases
Neurodegenerative diseases
05016 Huntington's disease
K04604 GRM5; metabotropic glutamate receptor 5
G protein-coupled receptors [BR:ko04030]
Class C. Metabotropic glutamate receptor family
Biogenic amine
Glutamate (metabotropic) [Table]
K04604 GRM5; metabotropic glutamate receptor 5
 |
| Other DBs |
|
| Genes |
HSA: | | PTR: | | MCC: | | MMU: | | RNO: | | CFA: | | AML: | | BTA: | | ECB: | | MDO: | | OAA: | | GGA: | | MGP: | | TGU: | | XTR: | | DRE: | | BFO: | | CQU: | | TCA: | | CEL: | | CBR: | | BMY: | | » show all
   |
| Reference |
|
| Authors |
Niswender CM, Conn PJ |
| Title |
Metabotropic glutamate receptors: physiology, pharmacology, and disease. |
| Journal |
Annu Rev Pharmacol Toxicol 50:295-322 (2010) |
| Reference |
|
| Authors |
Pin JP, Galvez T, Prezeau L |
| Title |
Evolution, structure, and activation mechanism of family 3/C G-protein-coupled receptors. |
| Journal |
Pharmacol Ther 98:325-54 (2003) |