KEGG   ORTHOLOGY: K04670Help
Entry
K04670                      KO                                     

Name
ACVR2A
Definition
activin receptor type-2A [EC:2.7.11.30]
Pathway
Cytokine-cytokine receptor interaction
TGF-beta signaling pathway
Signaling pathways regulating pluripotency of stem cells
Fluid shear stress and atherosclerosis
Module
M00679  
BMP signaling
M00681  
Activin signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04350 TGF-beta signaling pathway
    K04670  ACVR2A; activin receptor type-2A
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K04670  ACVR2A; activin receptor type-2A
 Cellular Processes
  Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K04670  ACVR2A; activin receptor type-2A
 Human Diseases
  Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    K04670  ACVR2A; activin receptor type-2A
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00679  BMP signaling
     K04670  ACVR2A; activin receptor type-2A
    M00681  Activin signaling
     K04670  ACVR2A; activin receptor type-2A
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     K04670  ACVR2A; activin receptor type-2A
Protein kinases [BR:ko01001]
 Serine/threonine protein kinases: TKL group
  TGFBR2 family [OT]
   K04670  ACVR2A; activin receptor type-2A
Enzyme-linked receptors [BR:ko01020]
 Receptor serine/threonine kinases
  Type II TGF-beta receptor
   K04670  ACVR2A; activin receptor type-2A
Cytokine receptors [BR:ko04050]
 TGF-beta receptors
  Type II TGF-beta receptor
   K04670  ACVR2A; activin receptor type-2A
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
92(ACVR2A)
PTR: 
459646(ACVR2A)
PPS: 
100978909(ACVR2A)
GGO: 
101126947(ACVR2A)
PON: 
100435220(ACVR2A)
NLE: 
100583170(ACVR2A)
MCC: 
707017(ACVR2A)
MCF: 
102121129(ACVR2A)
CSAB: 
103217052(ACVR2A)
RRO: 
104655489(ACVR2A)
RBB: 
108512386(ACVR2A)
CJC: 
100397767(ACVR2A)
SBQ: 
101036787(ACVR2A)
MMU: 
11480(Acvr2a)
RNO: 
29263(Acvr2a)
CGE: 
100774605(Acvr2a)
NGI: 
103727329(Acvr2a)
HGL: 
101707586(Acvr2a)
CCAN: 
109689204(Acvr2a)
OCU: 
100008631(ACVR2A)
TUP: 
102499226(ACVR2A)
CFA: 
476140(ACVR2A)
AML: 
100472026(ACVR2A)
UMR: 
103667704(ACVR2A)
FCA: 
101097750(ACVR2A)
PTG: 
102948807(ACVR2A)
AJU: 
106971526(ACVR2A)
BTA: 
281598(ACVR2A)
BOM: 
102269861(ACVR2A)
BIU: 
109567962(ACVR2A)
PHD: 
102338238(ACVR2A)
CHX: 
100860918(ACVR2A)
OAS: 
443304(ACVR2A)
SSC: 
397282(ACVR2A)
CFR: 
102518044(ACVR2A)
CDK: 
105084601(ACVR2A)
BACU: 
103002388(ACVR2A)
LVE: 
103079492(ACVR2A)
ECB: 
100049823(ACVR2A)
EPZ: 
103549990(ACVR2A)
EAI: 
106825091(ACVR2A)
MYB: 
102253638(ACVR2A)
MYD: 
102768276(ACVR2A)
HAI: 
109388998(ACVR2A)
RSS: 
109450286(ACVR2A)
PALE: 
102891559(ACVR2A)
LAV: 
100672302(ACVR2A)
MDO: 
100018756(ACVR2A)
SHR: 
100918537(ACVR2A)
OAA: 
100089503(ACVR2A)
GGA: 
396324(ACVR2A)
MGP: 
100545173(ACVR2A)
CJO: 
107317053(ACVR2A)
APLA: 
101789784(ACVR2A)
ACYG: 
106041002(ACVR2A)
TGU: 
100224301(ACVR2A)
GFR: 
102039219(ACVR2A)
FAB: 
101821260(ACVR2A)
PHI: 
102113171(ACVR2A)
CCW: 
104694095(ACVR2A)
FPG: 
101915701(ACVR2A)
FCH: 
102053325(ACVR2A)
CLV: 
102098638(ACVR2A)
AAM: 
106498516(ACVR2A)
ASN: 
102368733(ACVR2A)
AMJ: 
102562921(ACVR2A)
PSS: 
102454507(ACVR2A)
CMY: 
102945188(ACVR2A)
CPIC: 
101933615(ACVR2A)
ACS: 
100562173(acvr2a)
PBI: 
103055188(ACVR2A)
GJA: 
107108802(ACVR2A)
XLA: 
399283(acvr2a.L) 495087(acvr2a.S)
XTR: 
100216172(acvr2a)
NPR: 
108795499(ACVR2A)
DRE: 
553359(acvr2aa)
SRX: 
107705816 107705898 107709421 107724023
SANH: 
107666699 107673126 107675352 107691069
SGH: 
107555835 107572302 107582301 107601072
IPU: 
108266626 108272703(acvr2a)
TRU: 
101067920(acvr2a) 101071858 101073426
TNG: 
GSTEN00031859G001
LCO: 
104926240(acvr2a) 104935816 109141095
NCC: 
104960238(acvr2a)
MZE: 
101464704 101481875(acvr2a)
OLA: 
100049489(acvr2a)
XMA: 
102217256 102227541(acvr2a)
CSEM: 
103389624(acvr2a)
LCF: 
108873081 108874503 108888565
SASA: 
106574301 106575234 106582410 106586327
ELS: 
105016248 105022549
SFM: 
108924278 108929958
LCM: 
102354804(ACVR2A)
CMK: 
103180467(acvr2a)
SKO: 
100378736
TSP: 
Tsp_06484
HRO: 
HELRODRAFT_89946
OBI: 
106868971
SMM: 
Smp_080120.2
ADF: 
107351560
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1311955
  Authors
Matzuk MM, Bradley A
  Title
Cloning of the human activin receptor cDNA reveals high evolutionary conservation.
  Journal
Biochim Biophys Acta 1130:105-8 (1992)
DOI:10.1016/0167-4781(92)90472-C
  Sequence
[hsa:92]
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