KEGG ORTHOLOGY: K04670

ORTHOLOGY: K04670

Entry

K04670 KO

Name

ACVR2A

Definition

activin receptor type-2A [EC:2.7.11.30]

Pathway

ko04060	Cytokine-cytokine receptor interaction
ko04350	TGF-beta signaling pathway

Brite

KEGG Orthology (KO) [BR:ko00001]
Environmental Information Processing
  Signal transduction
   04350 TGF-beta signaling pathway
    K04670  ACVR2A; activin receptor type-2A
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K04670  ACVR2A; activin receptor type-2A
Enzymes [BR:ko01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     K04670  ACVR2A; activin receptor type-2A
Protein kinases [BR:ko01001]
Serine/threonine protein kinases: TKL group
  TGFBR2 family [Table]
   K04670  ACVR2A; activin receptor type-2A
Enzyme-linked receptors [BR:ko01020]
Receptor serine/threonine kinases
  Type II TGF-beta receptor
   K04670  ACVR2A; activin receptor type-2A
Cytokine receptors [BR:ko04050]
TGF-beta receptors
  Type II TGF-beta receptor
   K04670  ACVR2A; activin receptor type-2A

Other DBs

GO:

0016362

Genes

HSA:	92(ACVR2A)
PTR:	459646(ACVR2A)
PPS:	100978909(ACVR2A)
GGO:	101126947(ACVR2A)
PON:	100435220(ACVR2A)
MCC:	707017(ACVR2A)
MCF:	102121129(ACVR2A)
MMU:	11480(Acvr2a)
RNO:	29263(Acvr2a)
CGE:	100774605(Acvr2a)
HGL:	101707586(Acvr2a)
TUP:	102499226(ACVR2A)
CFA:	476140(ACVR2A)
AML:	100472026
FCA:	101097750(ACVR2A)
PTG:	102948807(ACVR2A)
BTA:	281598(ACVR2A)
BOM:	102269861(ACVR2A)
PHD:	102338238(ACVR2A)
CHX:	100860918(ACTR2)
SSC:	397282(ACVR2A)
CFR:	102518044(ACVR2A)
ECB:	100049823(ACVR2A)
MYB:	102253638(ACVR2A)
MYD:	102768276(ACVR2A)
PALE:	102891559(ACVR2A)
MDO:	100018756(ACVR2A)
SHR:	100918537(ACVR2A)
OAA:	100089503(ACVR2A)
GGA:	396324(ACVR2A)
MGP:	100545173
TGU:	100224301(ACVR2A)
FAB:	101821260(ACVR2A)
PHI:	102113171(ACVR2A)
APLA:	101789784(ACVR2A)
FPG:	101915701(ACVR2A)
FCH:	102053325(ACVR2A)
CLV:	102098638(ACVR2A)
ASN:	102368733(ACVR2A)
PSS:	102454507(ACVR2A)
CMY:	102945188(ACVR2A)
ACS:	100562173
XLA:	399283(acvr2a) 495087
XTR:	100216172(acvr2a)
DRE:	553359(acvr2aa)
TRU:	101067920 101071858 101073426
MZE:	101464704 101481875
OLA:	100049489(acvr2)
XMA:	102217256 102227541
LCM:	102354804(ACVR2A)
TSP:	Tsp_06484
SMM:	Smp_080120.2

» show all

Reference

PMID:18000526

Authors

Schmierer B, Hill CS

Title

TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility.

Journal

Nat Rev Mol Cell Biol 8:970-82 (2007)

Reference

PMID:9759503

Authors

Massague J.

Title

TGF-beta signal transduction.

Journal

Annu Rev Biochem 67:753-91 (1998)

All links

Ontology (7)   
   KEGG BRITE (6)   
   GO (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Drug (1)   
   KEGG DRUG (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (71)   
   KEGG GENES (57)   
   KEGG DGENES (3)   
   KEGG MGENES (4)   
   EGENES (6)   
   OC (1)   
Protein sequence (29)   
   UniProt (23)   
   SWISS-PROT (6)   
Literature (2)   
   PubMed (2)   
All databases (115)   

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