KEGG   ORTHOLOGY: K04670Help
Entry
K04670                      KO                                     

Name
ACVR2A
Definition
activin receptor type-2A [EC:2.7.11.30]
Pathway
Cytokine-cytokine receptor interaction
TGF-beta signaling pathway
Signaling pathways regulating pluripotency of stem cells
Fluid shear stress and atherosclerosis
Module
M00679  
BMP signaling
M00681  
Activin signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04350 TGF-beta signaling pathway
    K04670  ACVR2A; activin receptor type-2A
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K04670  ACVR2A; activin receptor type-2A
 Cellular Processes
  Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K04670  ACVR2A; activin receptor type-2A
 Human Diseases
  Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    K04670  ACVR2A; activin receptor type-2A
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00679  BMP signaling
     K04670  ACVR2A; activin receptor type-2A
    M00681  Activin signaling
     K04670  ACVR2A; activin receptor type-2A
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     K04670  ACVR2A; activin receptor type-2A
Protein kinases [BR:ko01001]
 Serine/threonine protein kinases: TKL group
  TGFBR2 family [OT]
   K04670  ACVR2A; activin receptor type-2A
Enzyme-linked receptors [BR:ko01020]
 Receptor serine/threonine kinases
  Type II TGF-beta receptor
   K04670  ACVR2A; activin receptor type-2A
Cytokine receptors [BR:ko04050]
 TGF-beta receptors
  Type II TGF-beta receptor
   K04670  ACVR2A; activin receptor type-2A
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
92(ACVR2A)
PTR: 
459646(ACVR2A)
PON: 
100435220(ACVR2A)
MCC: 
707017(ACVR2A)
RNO: 
29263(Acvr2a)
CFA: 
476140(ACVR2A)
BTA: 
281598(ACVR2A)
SSC: 
397282(ACVR2A)
ECB: 
100049823(ACVR2A)
MDO: 
100018756(ACVR2A)
OAA: 
100089503(ACVR2A)
GGA: 
396324(ACVR2A)
MGP: 
100545173(ACVR2A)
TGU: 
100224301(ACVR2A)
ACS: 
100562173(acvr2a)
XLA: 
399283(acvr2a.L) 495087(acvr2a.S)
XTR: 
100216172(acvr2a)
DRE: 
553359(acvr2aa)
CMK: 
103180467(acvr2a)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1311955
  Authors
Matzuk MM, Bradley A
  Title
Cloning of the human activin receptor cDNA reveals high evolutionary conservation.
  Journal
Biochim Biophys Acta 1130:105-8 (1992)
DOI:10.1016/0167-4781(92)90472-C
  Sequence
[hsa:92]

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