KEGG   ORTHOLOGY: K04671Help
Entry
K04671                      KO                                     

Name
BMPR2
Definition
bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04350  TGF-beta signaling pathway
ko04360  Axon guidance
ko04390  Hippo signaling pathway
ko04550  Signaling pathways regulating pluripotency of stem cells
ko05206  MicroRNAs in cancer
ko05418  Fluid shear stress and atherosclerosis
Module
M00679  BMP signaling
Disease
H01619  Primary pulmonary hypertension (PPH)
H01621  Pulmonary arterial hypertension (PAH)
H01866  Pulmonary veno-occlusive disease and pulmonary capillary hemangiomatosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04350 TGF-beta signaling pathway
    K04671  BMPR2; bone morphogenetic protein receptor type-2
   04390 Hippo signaling pathway
    K04671  BMPR2; bone morphogenetic protein receptor type-2
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K04671  BMPR2; bone morphogenetic protein receptor type-2
 Cellular Processes
  Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K04671  BMPR2; bone morphogenetic protein receptor type-2
 Organismal Systems
  Development
   04360 Axon guidance
    K04671  BMPR2; bone morphogenetic protein receptor type-2
 Human Diseases
  Cancers
   05206 MicroRNAs in cancer
    K04671  BMPR2; bone morphogenetic protein receptor type-2
  Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    K04671  BMPR2; bone morphogenetic protein receptor type-2
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00679  BMP signaling
     K04671  BMPR2; bone morphogenetic protein receptor type-2
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     K04671  BMPR2; bone morphogenetic protein receptor type-2
Protein kinases [BR:ko01001]
 Receptor serine/threonine kinases (RSTK): TKL group
  TGFBR2 family [OT]
   K04671  BMPR2; bone morphogenetic protein receptor type-2
BRITE hierarchy
Other DBs
GO: 0016362
Genes
HSA: 659(BMPR2)
PTR: 459885(BMPR2)
PPS: 100987362(BMPR2)
GGO: 101152104(BMPR2)
PON: 100441517(BMPR2)
NLE: 100599616(BMPR2)
MCC: 704088(BMPR2)
MCF: 102132657(BMPR2)
CSAB: 103217668(BMPR2)
RRO: 104680809(BMPR2)
RBB: 108537211(BMPR2)
CJC: 100402963(BMPR2)
SBQ: 101047869(BMPR2)
MMU: 12168(Bmpr2)
RNO: 140590(Bmpr2)
CGE: 100764519(Bmpr2)
NGI: 103736034(Bmpr2)
HGL: 101701138(Bmpr2)
CCAN: 109683698(Bmpr2)
OCU: 100350246(BMPR2)
TUP: 102472860(BMPR2)
CFA: 478875(BMPR2)
AML: 100483427(BMPR2)
UMR: 103659757(BMPR2)
ORO: 101386632(BMPR2)
FCA: 101096338(BMPR2)
PTG: 102972964(BMPR2)
AJU: 106978276(BMPR2)
BTA: 407127(BMPR2)
BOM: 102276585(BMPR2)
BIU: 109575608(BMPR2)
PHD: 102331981(BMPR2)
CHX: 102173240(BMPR2)
OAS: 101103793(BMPR2)
SSC: 100127483(BMPR2)
CFR: 102504117(BMPR2) 102518140
CDK: 105098972(BMPR2)
BACU: 103010629(BMPR2)
LVE: 103089843(BMPR2)
OOR: 101276638(BMPR2)
ECB: 100067195(BMPR2)
EPZ: 103549220(BMPR2)
EAI: 106824062(BMPR2)
MYB: 102255023(BMPR2)
MYD: 102769364(BMPR2)
HAI: 109379244(BMPR2)
RSS: 109445000(BMPR2)
PALE: 102882003(BMPR2)
LAV: 100661600(BMPR2)
TMU: 101348356
MDO: 100018765(BMPR2)
SHR: 100925781(BMPR2)
OAA: 100077247(BMPR2)
GGA: 374147(BMPR2)
MGP: 100551416(BMPR2)
CJO: 107316544(BMPR2)
APLA: 101793707(BMPR2)
ACYG: 106030098(BMPR2)
TGU: 100227149(BMPR2)
GFR: 102043611(BMPR2)
FAB: 101806244(BMPR2)
PHI: 102110191(BMPR2)
PMAJ: 107207396(BMPR2)
CCW: 104693787(BMPR2)
FPG: 101919199(BMPR2)
FCH: 102046415(BMPR2)
CLV: 102086688(BMPR2)
EGZ: 104130476(BMPR2)
AAM: 106492422(BMPR2)
ASN: 102370042(BMPR2)
AMJ: 102577319(BMPR2)
PSS: 102456232(BMPR2)
CMY: 102929585(BMPR2)
CPIC: 101951829(BMPR2)
ACS: 100553521(bmpr2)
PVT: 110088189(BMPR2)
PBI: 103060123(BMPR2)
GJA: 107113314(BMPR2)
XLA: 108701455(bmpr2.L) 397981(bmpr2.S)
XTR: 100494339(bmpr2)
NPR: 108785044(BMPR2)
DRE: 555655(bmpr2b) 562822(bmpr2a)
IPU: 108266402(bmpr2) 108272897(BMPR2)
AMEX: 103025384(amhr2) 103041475 103046530(bmpr2)
TRU: 101069366(bmpr2)
LCO: 104926387(bmpr2) 104931750
NCC: 104958413(bmpr2) 104958414
OLA: 100125447(misrii) 101167856(bmpr2)
NFU: 107377073(bmpr2) 107391016
CSEM: 103386397(amhr2) 103389452(bmpr2)
HCQ: 109507796(bmpr2)
ELS: 105007022 105020079(bmpr2)
SFM: 108920640 108928424(amhr2) 108942470(bmpr2)
LCM: 102353534(BMPR2) 102366672
CMK: 103172985 103189999(bmpr2)
SPU: 586095
APLC: 110978100
SKO: 102810094
DME: Dmel_CG10776(wit)
DSI: Dsimw501_GD13298(Dsim_GD13298)
MDE: 101888345
AAG: 110676109
AME: 413895(wit)
BIM: 100743451
BTER: 100647132
SOC: 105205018
AEC: 105154345
ACEP: 105618737
PBAR: 105429516
HST: 105189198
CFO: 105259096
LHU: 105676358
PGC: 109859096
NVI: 100121252(wit)
TCA: 663692(wit)
DPA: 109536255
NVL: 108563153
BMOR: 101744534
PMAC: 106715185
PRAP: 110997216
ZNE: 110830124
FCD: 110844532
MYI: 110442406
OBI: 106882102
LAK: 106170149
EPA: 110238334
ADF: 107351567
 » show all
TaxonomyKoalaUniProt
Reference
PMID:7791754
  Authors
Liu F, Ventura F, Doody J, Massague J.
  Title
Human type II receptor for bone morphogenic proteins (BMPs): extension of the two-kinase receptor model to the BMPs.
  Journal
Mol Cell Biol 15:3479-86 (1995)
DOI:10.1128/MCB.15.7.3479
  Sequence
[hsa:659]

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