KEGG   ORTHOLOGY: K04671Help
Entry
K04671                      KO                                     

Name
BMPR2
Definition
bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
Pathway
Cytokine-cytokine receptor interaction
TGF-beta signaling pathway
Axon guidance
Hippo signaling pathway
Signaling pathways regulating pluripotency of stem cells
MicroRNAs in cancer
Fluid shear stress and atherosclerosis
Module
M00679  
BMP signaling
Disease
H01619  
Primary pulmonary hypertension (PPH)
H01621  
Pulmonary arterial hypertension (PAH)
H01866  
Pulmonary veno-occlusive disease and pulmonary capillary hemangiomatosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04350 TGF-beta signaling pathway
    K04671  BMPR2; bone morphogenetic protein receptor type-2
   04390 Hippo signaling pathway
    K04671  BMPR2; bone morphogenetic protein receptor type-2
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K04671  BMPR2; bone morphogenetic protein receptor type-2
 Cellular Processes
  Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K04671  BMPR2; bone morphogenetic protein receptor type-2
 Organismal Systems
  Development
   04360 Axon guidance
    K04671  BMPR2; bone morphogenetic protein receptor type-2
 Human Diseases
  Cancers
   05206 MicroRNAs in cancer
    K04671  BMPR2; bone morphogenetic protein receptor type-2
  Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    K04671  BMPR2; bone morphogenetic protein receptor type-2
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00679  BMP signaling
     K04671  BMPR2; bone morphogenetic protein receptor type-2
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     K04671  BMPR2; bone morphogenetic protein receptor type-2
Protein kinases [BR:ko01001]
 Serine/threonine protein kinases: TKL group
  TGFBR2 family [OT]
   K04671  BMPR2; bone morphogenetic protein receptor type-2
Enzyme-linked receptors [BR:ko01020]
 Receptor serine/threonine kinases
  Type II TGF-beta receptor
   K04671  BMPR2; bone morphogenetic protein receptor type-2
Cytokine receptors [BR:ko04050]
 TGF-beta receptors
  Type II TGF-beta receptor
   K04671  BMPR2; bone morphogenetic protein receptor type-2
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
659(BMPR2)
PTR: 
459885(BMPR2)
PPS: 
100987362(BMPR2)
GGO: 
101152104(BMPR2)
PON: 
100441517(BMPR2)
NLE: 
100599616(BMPR2)
MCC: 
704088(BMPR2)
MCF: 
102132657(BMPR2)
CSAB: 
103217668(BMPR2)
RRO: 
104680809(BMPR2)
RBB: 
108537211(BMPR2)
CJC: 
100402963(BMPR2)
SBQ: 
101047869(BMPR2)
MMU: 
12168(Bmpr2)
RNO: 
140590(Bmpr2)
CGE: 
100764519(Bmpr2)
NGI: 
103736034(Bmpr2)
HGL: 
101701138(Bmpr2)
CCAN: 
109683698(Bmpr2)
OCU: 
100350246(BMPR2)
TUP: 
102472860(BMPR2)
CFA: 
478875(BMPR2)
AML: 
100483427(BMPR2)
UMR: 
103659757(BMPR2)
ORO: 
101386632(BMPR2)
FCA: 
101096338(BMPR2)
PTG: 
102972964(BMPR2)
AJU: 
106978276(BMPR2)
BTA: 
407127(BMPR2)
BOM: 
102276585(BMPR2)
BIU: 
109575608(BMPR2)
PHD: 
102331981(BMPR2)
CHX: 
102173240(BMPR2)
OAS: 
101103793(BMPR2)
SSC: 
100127483(BMPR2)
CFR: 
CDK: 
105098972(BMPR2)
BACU: 
103010629(BMPR2)
LVE: 
103089843(BMPR2)
ECB: 
100067195(BMPR2)
EPZ: 
103549220(BMPR2)
EAI: 
106824062(BMPR2)
MYB: 
102255023(BMPR2)
MYD: 
102769364(BMPR2)
HAI: 
109379244(BMPR2)
RSS: 
109445000(BMPR2)
PALE: 
102882003(BMPR2)
LAV: 
100661600(BMPR2)
TMU: 
MDO: 
100018765(BMPR2)
SHR: 
100925781(BMPR2)
OAA: 
100077247(BMPR2)
GGA: 
374147(BMPR2)
MGP: 
100551416(BMPR2)
CJO: 
107316544(BMPR2)
APLA: 
101793707(BMPR2)
ACYG: 
106030098(BMPR2)
TGU: 
100227149(BMPR2)
GFR: 
102043611(BMPR2)
FAB: 
101806244(BMPR2)
PHI: 
102110191(BMPR2)
PMAJ: 
107207396(BMPR2)
CCW: 
104693787(BMPR2)
FPG: 
101919199(BMPR2)
FCH: 
102046415(BMPR2)
CLV: 
102086688(BMPR2)
EGZ: 
104130476(BMPR2)
AAM: 
106492422(BMPR2)
ASN: 
102370042(BMPR2)
AMJ: 
102577319(BMPR2)
PSS: 
102456232(BMPR2)
CMY: 
102929585(BMPR2)
CPIC: 
101951829(BMPR2)
ACS: 
100553521(bmpr2)
PVT: 
110088189(BMPR2)
PBI: 
103060123(BMPR2)
GJA: 
107113314(BMPR2)
XLA: 
108701455(bmpr2.L) 397981(bmpr2.S)
XTR: 
100494339(bmpr2)
NPR: 
108785044(BMPR2)
DRE: 
555655(bmpr2b) 562822(bmpr2a)
SRX: 
SANH: 
SGH: 
CCAR: 
IPU: 
108266402(bmpr2) 108272897(BMPR2)
AMEX: 
TRU: 
101069366(bmpr2)
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
100125447(misrii) 101167856(bmpr2)
XMA: 
PRET: 
NFU: 
CSEM: 
103386397(amhr2) 103389452(bmpr2)
LCF: 
HCQ: 
109507796(bmpr2)
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
CMK: 
SPU: 
APLC: 
SKO: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
Dsimw501_GD13298(Dsim_GD13298)
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
CQU: 
AME: 
413895(wit)
BIM: 
BTER: 
SOC: 
AEC: 
ACEP: 
PBAR: 
HST: 
CFO: 
LHU: 
PGC: 
NVI: 
TCA: 
663692(wit)
DPA: 
NVL: 
BMOR: 
DPL: 
PMAC: 
PRAP: 
PXY: 
ZNE: 
FCD: 
ISC: 
HRO: 
LGI: 
CRG: 
MYI: 
OBI: 
LAK: 
NVE: 
EPA: 
ADF: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:7791754
  Authors
Liu F, Ventura F, Doody J, Massague J.
  Title
Human type II receptor for bone morphogenic proteins (BMPs): extension of the two-kinase receptor model to the BMPs.
  Journal
Mol Cell Biol 15:3479-86 (1995)
DOI:10.1128/MCB.15.7.3479
  Sequence
[hsa:659]

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