KEGG   ORTHOLOGY: K04671Help
Entry
K04671                      KO                                     

Name
BMPR2
Definition
bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
Pathway
Cytokine-cytokine receptor interaction
TGF-beta signaling pathway
Hippo signaling pathway
Signaling pathways regulating pluripotency of stem cells
MicroRNAs in cancer
Module
M00679  
BMP signaling
Disease
H01300  
Primary pulmonary hypertension (PPH)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04350 TGF-beta signaling pathway
    K04671  BMPR2; bone morphogenetic protein receptor type-2
   04390 Hippo signaling pathway
    K04671  BMPR2; bone morphogenetic protein receptor type-2
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K04671  BMPR2; bone morphogenetic protein receptor type-2
 Cellular Processes
  Cellular commiunity
   04550 Signaling pathways regulating pluripotency of stem cells
    K04671  BMPR2; bone morphogenetic protein receptor type-2
 Human Diseases
  Cancers
   05206 MicroRNAs in cancer
    K04671  BMPR2; bone morphogenetic protein receptor type-2
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00679  BMP signaling
     K04671  BMPR2; bone morphogenetic protein receptor type-2
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     K04671  BMPR2; bone morphogenetic protein receptor type-2
Protein kinases [BR:ko01001]
 Serine/threonine protein kinases: TKL group
  TGFBR2 family [OT]
   K04671  BMPR2; bone morphogenetic protein receptor type-2
Enzyme-linked receptors [BR:ko01020]
 Receptor serine/threonine kinases
  Type II TGF-beta receptor
   K04671  BMPR2; bone morphogenetic protein receptor type-2
Cytokine receptors [BR:ko04050]
 TGF-beta receptors
  Type II TGF-beta receptor
   K04671  BMPR2; bone morphogenetic protein receptor type-2
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
659(BMPR2)
PTR: 
459885(BMPR2)
PPS: 
100987362(BMPR2)
GGO: 
PON: 
100441517(BMPR2)
NLE: 
100599616(BMPR2)
MCC: 
704088(BMPR2)
MCF: 
102132657(BMPR2)
CJC: 
100402963(BMPR2)
MMU: 
12168(Bmpr2)
RNO: 
140590(Bmpr2)
CGE: 
100764519(Bmpr2)
NGI: 
103736034(Bmpr2)
HGL: 
101701138(Bmpr2)
OCU: 
100350246(BMPR2)
TUP: 
102472860(BMPR2)
CFA: 
478875(BMPR2)
AML: 
100483427(BMPR2)
UMR: 
103659757(BMPR2)
FCA: 
101096338(BMPR2)
PTG: 
102972964(BMPR2)
BTA: 
407127(BMPR2)
BOM: 
102276585(BMPR2)
PHD: 
102331981(BMPR2)
CHX: 
102173240(BMPR2)
OAS: 
101103793(BMPR2)
SSC: 
100127483(BMPR2)
CFR: 
BACU: 
103010629(BMPR2)
LVE: 
103089843(BMPR2)
ECB: 
100067195(BMPR2)
MYB: 
102255023(BMPR2)
MYD: 
102769364(BMPR2)
PALE: 
102882003(BMPR2)
MDO: 
100018765(BMPR2)
SHR: 
100925781(BMPR2)
OAA: 
100077247(BMPR2)
GGA: 
374147(BMPR2)
MGP: 
APLA: 
101793707(BMPR2)
TGU: 
100227149(BMPR2)
FAB: 
101806244(BMPR2)
PHI: 
102110191(BMPR2)
FPG: 
101919199(BMPR2)
FCH: 
102046415(BMPR2)
CLV: 
102086688(BMPR2)
ASN: 
102370042(BMPR2)
AMJ: 
102577319(BMPR2)
PSS: 
102456232(BMPR2)
CMY: 
102929585(BMPR2)
ACS: 
100553521(bmpr2)
PBI: 
103060123(BMPR2)
XLA: 
397981(bmpr2)
XTR: 
100494339(bmpr2)
DRE: 
555655(bmpr2b) 562822(bmpr2a)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
SPU: 
DAN: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
CQU: 
AME: 
413895(wit)
NVI: 
TCA: 
663692(wit)
ISC: 
HRO: 
LGI: 
NVE: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Schmierer B, Hill CS
  Title
TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility.
  Journal
Nat Rev Mol Cell Biol 8:970-82 (2007)
Reference
PMID:9759503
  Authors
Massague J.
  Title
TGF-beta signal transduction.
  Journal
Annu Rev Biochem 67:753-91 (1998)

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