KEGG   ORTHOLOGY: K04675Help
Entry
K04675                      KO                                     

Name
ACVR1, ALK2
Definition
activin receptor type-1 [EC:2.7.11.30]
Pathway
Cytokine-cytokine receptor interaction
TGF-beta signaling pathway
Signaling pathways regulating pluripotency of stem cells
Module
M00679  
BMP signaling
Disease
H00430  
Fibrodysplasia ossificans progressiva (FOP)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04350 TGF-beta signaling pathway
    K04675  ACVR1, ALK2; activin receptor type-1
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K04675  ACVR1, ALK2; activin receptor type-1
 Cellular Processes
  Cellular commiunity
   04550 Signaling pathways regulating pluripotency of stem cells
    K04675  ACVR1, ALK2; activin receptor type-1
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00679  BMP signaling
     K04675  ACVR1, ALK2; activin receptor type-1
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     K04675  ACVR1, ALK2; activin receptor type-1
Protein kinases [BR:ko01001]
 Serine/threonine protein kinases: TKL group
  TGFBR1 family [OT]
   K04675  ACVR1, ALK2; activin receptor type-1
Enzyme-linked receptors [BR:ko01020]
 Receptor serine/threonine kinases
  Type I TGF-beta receptor
   K04675  ACVR1, ALK2; activin receptor type-1
Cytokine receptors [BR:ko04050]
 TGF-beta receptors
  Type I TGF-beta receptor
   K04675  ACVR1, ALK2; activin receptor type-1
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
90(ACVR1)
PTR: 
470565(ACVR1)
PPS: 
100967435(ACVR1)
GGO: 
101124161(ACVR1)
PON: 
100455728(ACVR1)
NLE: 
100594249(ACVR1)
MCC: 
697935(ACVR1)
MCF: 
102134051(ACVR1)
CJC: 
100406595(ACVR1)
MMU: 
11477(Acvr1)
RNO: 
79558(Acvr1)
CGE: 
100758565(Acvr1)
NGI: 
103741053(Acvr1)
HGL: 
101711343(Acvr1)
OCU: 
100355119(ACVR1)
TUP: 
102471973(ACVR1)
CFA: 
478757(ACVR1)
AML: 
100476325(ACVR1)
UMR: 
103659482(ACVR1)
FCA: 
101091298(ACVR1)
PTG: 
102955784(ACVR1)
BTA: 
338068(ACVR1)
BOM: 
102275369(ACVR1)
PHD: 
102325720(ACVR1)
CHX: 
100860926(ACTR1A)
OAS: 
443161(ACVR1)
SSC: 
100152307(ACVR1)
CFR: 
102512007(ACVR1)
BACU: 
102998999(ACVR1)
LVE: 
103085459(ACVR1)
ECB: 
100050899(ACVR1)
MYB: 
102263759(ACVR1)
MYD: 
102767973(ACVR1)
PALE: 
102880880(ACVR1)
MDO: 
100021438(ACVR1)
SHR: 
100928279(ACVR1)
OAA: 
100077006(ACVR1)
GGA: 
395246(ACVR1)
MGP: 
100546560(ACVR1)
APLA: 
101793792(ACVR1)
TGU: 
100230545(ACVR1)
GFR: 
102040859(ACVR1)
FAB: 
101818057(ACVR1)
PHI: 
102109524(ACVR1)
CCW: 
104694116(ACVR1)
FPG: 
101911977(ACVR1)
FCH: 
102053092(ACVR1)
CLV: 
102087076(ACVR1)
ASN: 
AMJ: 
PSS: 
102455326(ACVR1)
CMY: 
102948189(ACVR1)
ACS: 
100552279(acvr1)
PBI: 
103049229(ACVR1)
XLA: 
399083(acvr1-a) 399103(acvr1-b)
XTR: 
550111(acvr1)
DRE: 
30615(acvr1l)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
BFO: 
CIN: 
778776(tgfbr-ia)
SPU: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
CQU: 
AME: 
725711(sax)
NVI: 
TCA: 
658545(sax)
BMOR: 
API: 
PHU: 
ISC: 
HRO: 
LGI: 
NVE: 
HMG: 
TAD: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Schmierer B, Hill CS
  Title
TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility.
  Journal
Nat Rev Mol Cell Biol 8:970-82 (2007)
Reference
PMID:9759503
  Authors
Massague J.
  Title
TGF-beta signal transduction.
  Journal
Annu Rev Biochem 67:753-91 (1998)

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