| Entry |
|
|---|
| Name |
ACVR1, ALK2
|
|---|
| Definition |
|
|---|
| Pathway |
| Cytokine-cytokine receptor interaction | | TGF-beta signaling pathway |
|
|---|
| Disease |
| Fibrodysplasia ossificans progressiva (FOP) |
|
|---|
| Brite |
KEGG Orthology (KO) [BR:ko00001]
Environmental Information Processing
Signal transduction
04350 TGF-beta signaling pathway
K04675 ACVR1, ALK2; activin receptor type-1
Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
K04675 ACVR1, ALK2; activin receptor type-1
Enzymes [BR:ko01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.30 receptor protein serine/threonine kinase
K04675 ACVR1, ALK2; activin receptor type-1
Protein kinases [BR:ko01001]
Serine/threonine protein kinases: TKL group
TGFBR1 family
K04675 ACVR1, ALK2; activin receptor type-1
Enzyme-linked receptors [BR:ko01020]
Receptor serine/threonine kinases
Type I TGF-beta receptor
K04675 ACVR1, ALK2; activin receptor type-1
Cytokine receptors [BR:ko04050]
TGF-beta receptors
Type I TGF-beta receptor
K04675 ACVR1, ALK2; activin receptor type-1
 |
|---|
| Other DBs |
|
|---|
| Genes |
HSA: | | PTR: | | PPS: | | GGO: | | PON: | | MCC: | | MMU: | | RNO: | | CFA: | | AML: | | FCA: | | BTA: | | SSC: | | ECB: | | MDO: | | SHR: | | OAA: | | GGA: | | TGU: | | XLA: | | XTR: | | DRE: | | TRU: | | OLA: | | BFO: | | CIN: | | SPU: | | DME: | | DPO: | | DAN: | | DER: | | DPE: | | DSE: | | DSI: | | DWI: | | DYA: | | DGR: | | DMO: | | DVI: | | AGA: | | AAG: | | CQU: | | AME: | | NVI: | | TCA: | | PHU: | | ISC: | | NVE: | | HMG: | |
» show all
   |
|---|
| Reference |
|
|---|
| Authors |
Schmierer B, Hill CS |
|---|
| Title |
TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility. |
|---|
| Journal |
Nat Rev Mol Cell Biol 8:970-82 (2007) |
|---|
| Reference |
|
|---|
| Authors |
Massague J. |
|---|
| Title |
TGF-beta signal transduction. |
|---|
| Journal |
Annu Rev Biochem 67:753-91 (1998) |
|---|
