KEGG   ORTHOLOGY: K04685Help
Entry
K04685                      KO                                     

Name
CDKN2B, P15, INK4B
Definition
cyclin-dependent kinase inhibitor 2B
Pathway
FoxO signaling pathway
Cell cycle
TGF-beta signaling pathway
HTLV-I infection
Pathways in cancer
Viral carcinogenesis
Small cell lung cancer
Disease
H00015  
Malignant pleural mesothelioma
H00036  
Osteosarcoma
H00409  
Type II diabetes mellitus
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04350 TGF-beta signaling pathway
    K04685  CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
   04068 FoxO signaling pathway
    K04685  CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
 Cellular Processes
  Cell growth and death
   04110 Cell cycle
    K04685  CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K04685  CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
   05203 Viral carcinogenesis
    K04685  CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
   05222 Small cell lung cancer
    K04685  CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
  Infectious diseases
   05166 HTLV-I infection
    K04685  CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
1030(CDKN2B)
PTR: 
473204(CDKN2B)
PPS: 
100976219(CDKN2B)
GGO: 
101146090(CDKN2B)
PON: 
NLE: 
100593298(CDKN2B)
MCC: 
709209(CDKN2B)
MCF: 
MMU: 
12579(Cdkn2b)
RNO: 
25164(Cdkn2b)
HGL: 
TUP: 
CFA: 
481563(CDKN2B)
AML: 
FCA: 
101087014(CDKN2B)
PTG: 
102959282(CDKN2B)
BTA: 
527124(CDKN2B)
CHX: 
102172895(CDKN2B)
OAS: 
101107164(CDKN2B)
SSC: 
397227(CDKN2B)
CFR: 
102517211(CDKN2B)
BACU: 
103011925(CDKN2B)
LVE: 
103089606(CDKN2B)
ECB: 
100034122(CDKN2B)
MYB: 
102260903(CDKN2B)
MYD: 
PALE: 
102893142(CDKN2B)
MDO: 
100021947(CDKN2B)
GGA: 
395076(CDKN2B)
TGU: 
FAB: 
AMJ: 
102567321(CDKN2B)
CMY: 
PBI: 
103066227(CDKN2B)
XLA: 
779240(cdkn2b)
XTR: 
448767(cdkn2b)
TRU: 
101062640(cdkn2A/B)
MZE: 
XMA: 
102224758(CDNK2X)
LCM: 
102356560(CDKN2B)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Canepa ET, Scassa ME, Ceruti JM, Marazita MC, Carcagno AL, Sirkin PF, Ogara MF
  Title
INK4 proteins, a family of mammalian CDK inhibitors with novel biological functions.
  Journal
IUBMB Life 59:419-26 (2007)

DBGET integrated database retrieval system