KEGG   ORTHOLOGY: K04685Help
Entry
K04685                      KO                                     

Name
CDKN2B, P15, INK4B
Definition
cyclin-dependent kinase inhibitor 2B
Pathway
FoxO signaling pathway
Cell cycle
TGF-beta signaling pathway
HTLV-I infection
Pathways in cancer
Viral carcinogenesis
Small cell lung cancer
Disease
H00015  
Malignant pleural mesothelioma
H00036  
Osteosarcoma
H00409  
Type II diabetes mellitus
H01463  
Mycosis fungoides
H01556  
Meningioma
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04350 TGF-beta signaling pathway
    K04685  CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
   04068 FoxO signaling pathway
    K04685  CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
 Cellular Processes
  Cell growth and death
   04110 Cell cycle
    K04685  CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K04685  CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
   05203 Viral carcinogenesis
    K04685  CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
   05222 Small cell lung cancer
    K04685  CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
  Infectious diseases
   05166 HTLV-I infection
    K04685  CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
1030(CDKN2B)
PTR: 
473204(CDKN2B)
PPS: 
100976219(CDKN2B)
GGO: 
101146090(CDKN2B)
PON: 
100459175(CDKN2B)
NLE: 
100593298(CDKN2B)
MCC: 
709209(CDKN2B)
MCF: 
101866825(CDKN2B)
RRO: 
104654271(CDKN2B)
CJC: 
100392363(CDKN2B)
MMU: 
12579(Cdkn2b)
RNO: 
25164(Cdkn2b)
NGI: 
103730664(Cdkn2b)
HGL: 
OCU: 
100351874(CDKN2B)
TUP: 
CFA: 
481563(CDKN2B)
AML: 
100473431(CDKN2B)
UMR: 
FCA: 
101087014(CDKN2B)
BTA: 
527124(CDKN2B)
CHX: 
102172895(CDKN2B)
OAS: 
101107164(CDKN2B)
SSC: 
397227(CDKN2B)
CFR: 
102517211(CDKN2B)
BACU: 
103011925(CDKN2B)
LVE: 
103089606(CDKN2B)
ECB: 
100034122(CDKN2B)
MYB: 
102260903(CDKN2B)
MYD: 
PALE: 
102893142(CDKN2B)
MDO: 
100021947(CDKN2B)
GGA: 
395076(CDKN2B)
CJO: 
107306707(CDKN2B)
TGU: 
FAB: 
PHI: 
PSS: 
CMY: 
ACS: 
100562668(cdkn2b)
PBI: 
GJA: 
XLA: 
779240(cdkn2b)
XTR: 
448767(cdkn2b)
TRU: 
101062640(cdkn2A/B)
MZE: 
XMA: 
102224758(cdkn2b)
LCM: 
102356560(CDKN2B)
CMK: 
103182848(p16INK4a)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Canepa ET, Scassa ME, Ceruti JM, Marazita MC, Carcagno AL, Sirkin PF, Ogara MF
  Title
INK4 proteins, a family of mammalian CDK inhibitors with novel biological functions.
  Journal
IUBMB Life 59:419-26 (2007)
Reference
PMID:8078588
  Authors
Hannon GJ, Beach D
  Title
p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest.
  Journal
Nature 371:257-61 (1994)
  Sequence
[hsa:1030]

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