KEGG   ORTHOLOGY: K04710Help
Entry
K04710                      KO                                     

Name
CERS
Definition
ceramide synthetase [EC:2.3.1.24]
Pathway
Sphingolipid metabolism
Module
M00094  
Ceramide biosynthesis
M00099  
Sphingosine biosynthesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Lipid metabolism
   00600 Sphingolipid metabolism
    K04710  CERS; ceramide synthetase
KEGG modules [BR:ko00002]
 Pathway module
  Carbohydrate and lipid metabolism
   Lipid metabolism
    M00094  Ceramide biosynthesis
     K04710  CERS; ceramide synthetase
    M00099  Sphingosine biosynthesis
     K04710  CERS; ceramide synthetase
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.24  sphingosine N-acyltransferase
     K04710  CERS; ceramide synthetase
BRITE hierarchy
Other DBs
Genes
HSA: 
10715(CERS1) 204219(CERS3) 253782(CERS6) 29956(CERS2) 79603(CERS4) 91012(CERS5)
PTR: 
451891(LASS5) 453683(LASS3) 456435(LASS4) 468773(LASS1) 469482(LASS2) 741293(LASS6)
PPS: 
100968130(CERS1) 100973710(CERS4) 100973768(CERS2) 100980816(CERS5) 100985038(CERS6) 100994802(CERS3)
GGO: 
PON: 
100174286(LASS2) 100437726(CERS4) 100447528 100451535(CERS3) 100452162(CERS6) 100454836(CERS5)
MCC: 
693696(LASS3) 704953(LASS6) 706728(LASS4) 713449(LASS5) 716180(LASS2)
MCF: 
MMU: 
241447(Cers6) 545975(Cers3) 67260(Cers4) 71949(Cers5) 76893(Cers2) 93898(Cers1)
RNO: 
290658(Cers1) 304208(Cers4) 310667(Cers2) 366065(Cers6) 366984(Cers5) 499174(Cers3)
CGE: 
100758196(Cers4) 100761613(Cers6) 100765511(Cers1) 100765986(Cers2) 100770521(Cers3) 100774213(Cers5)
HGL: 
101701089(Cers5) 101702770(Cers3) 101705418(Cers1) 101713278(Cers6) 101715336(Cers4) 101716285(Cers2)
TUP: 
102474397(CERS5) 102475021(CERS3) 102475765(CERS1) 102484493(CERS6) 102495526(CERS4) 102502685(CERS2)
CFA: 
477611(CERS5) 483187(CERS2) 485008(CERS4) 488387(CERS6) 607925(CERS3) 609789(CERS1)
AML: 
FCA: 
101084386(CERS6) 101087243(CERS5) 101089084(CERS1) 101093918(CERS4) 101094362(CERS2) 101099301(CERS3)
PTG: 
102948771(CERS6) 102961418(CERS1) 102961799(CERS5) 102968533(CERS3) 102970444(CERS2) 102972870(CERS4)
BTA: 
505233(CERS4) 530776(CERS5) 539223(CERS2) 614354(CERS3) 615296(CERS1) 616901(CERS6)
BOM: 
102264858(CERS2) 102269743(CERS1) 102271413(CERS5) 102275684(CERS4) 102282095(CERS6) 102282323(CERS3)
PHD: 
102318840(CERS4) 102324961(CERS5) 102325529(CERS6) 102330749(CERS2) 102334903(CERS1) 102345046(CERS3)
CHX: 
102169911(CERS3) 102170388(CERS5) 102174737(CERS4) 102176466(CERS6) 102182556(CERS2) 102189571(CERS1)
SSC: 
100126279(LASS6) 100127167(LASS4) 100152265(CERS3) 100156737(CERS2) 100525450(CERS1) 100626198
CFR: 
102505196(CERS3) 102507344(CERS1) 102507747(CERS5) 102509169(CERS6) 102511821(CERS2) 102519510(CERS4)
BACU: 
103003098(CERS1) 103007274(CERS5) 103008265(CERS6) 103009608(CERS2) 103009742(CERS4) 103016103(CERS3)
LVE: 
103069846(CERS4) 103076535(CERS6) 103076923(CERS2) 103082414(CERS3) 103088889(CERS5) 103091398(CERS1)
ECB: 
100050135(CERS3) 100052305(CERS6) 100055037(CERS2) 100059999(CERS5) 100066949(CERS4) 100069594(CERS1)
MYB: 
102242969(CERS3) 102246479(CERS6) 102249252(CERS1) 102250642(CERS4) 102256999(CERS2) 102262839(CERS5)
MYD: 
102759130(CERS3) 102760303(CERS5) 102767770(CERS4) 102769776(CERS1) 102772688(CERS6) 102772826(CERS2)
PALE: 
102880099(CERS5) 102885878(CERS1) 102885951(CERS2) 102889613(CERS3) 102890907(CERS4) 102896376(CERS6)
MDO: 
100014952(CERS2) 100016686(CERS1) 100020588(CERS3) 100024030(CERS6) 100025505
SHR: 
OAA: 
100078502(CERS1) 100083235(CERS6) 100090289(CERS4) 100090484(CERS3)
GGA: 
100857262 100859441 420050(LASS4) 420118(CERS1) 426648(CERS3) 426879(CERS5) 428318(LASS4) 771503(CERS6)
MGP: 
TGU: 
100217479 100224527(CERS3) 100225623(CERS6) 100228761(CERS2) 100230030(CERS1) 100231332(CERS5)
FAB: 
101809766(CERS1) 101812995 101816156(CERS5) 101818464(CERS3) 101818852(CERS6)
PHI: 
102104999(CERS3) 102105774(CERS5) 102106078(CERS2) 102107684(CERS1) 102111990(CERS6) 102114515
APLA: 
FPG: 
101913508(CERS5) 101915529(CERS3) 101919852(CERS2) 101920423(CERS6) 101922241 101923637(CERS1)
FCH: 
102046386(CERS1) 102047202 102049480(CERS2) 102052030(CERS5) 102052115(CERS6) 102054381(CERS3)
CLV: 
102084875 102089975(CERS6) 102090020(CERS3) 102090443(CERS5) 102098532(CERS1)
ASN: 
102368101 102380256(CERS6) 102383180(CERS2) 102383725(CERS5) 102384359(CERS1) 102388749(CERS3)
AMJ: 
PSS: 
102445918(CERS2) 102447507 102449546(CERS1) 102452005(CERS5) 102452581(CERS3) 102460649(CERS6)
CMY: 
102929497(CERS2) 102935204(CERS1) 102935736(CERS6) 102939527(CERS5) 102939917(CERS3) 102942007
ACS: 
PBI: 
XLA: 
379135(cers2) 399185(trh4) 444162(cers3) 495501(cers5)
XTR: 
100036728(cers2) 100101657(cers5) 100379773(cers4) 100485129(cers1) 100489264(cers6) 448139(cers3)
DRE: 
100330155 259251(cers2a) 323020(cers5) 564867(cers6) 568169(cers1)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
103172411 103176381(cers6) 103181964(cers1) 103183569(cers4) 103187682(cers3) 103190303(cers5)
BFO: 
CIN: 
100101810(lag1-like3) 100184115 778663(lag1-like1)
SPU: 
DME: 
Dmel_CG3576(schlank)
DPO: 
DER: 
DPE: 
DSE: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
CQU: 
AME: 
727350(Lag1)
NVI: 
100124217(Lag1)
TCA: 
BMOR: 
API: 
PHU: 
ISC: 
CEL: 
CBR: 
CBG13635(Cbr-lagr-1) CBG14524(Cbr-hyl-2) CBG15635(Cbr-hyl-1)
BMY: 
LOA: 
TSP: 
SMM: 
NVE: 
HMG: 
TAD: 
AQU: 
ALY: 
CRB: 
EUS: 
CIT: 
CIC: 
TCC: 
GMX: 
PVU: 
MTR: 
CAM: 
FVE: 
PPER: 
CSV: 
RCU: 
POP: 
POPTR_0008s11300g(POPTRDRAFT_1084995) POPTR_0010s14480g(POPTRDRAFT_769737) POPTR_0015s06530g
VVI: 
SLY: 
101252975 543781(asc-1) 778364(Asc-1)
SOT: 
DOSA: 
Os02t0728300-00(Os02g0728300)
OBR: 
BDI: 
SBI: 
SORBI_02g023420(SORBIDRAFT_02g023420) SORBI_04g024150(SORBIDRAFT_04g024150) SORBI_04g029190(SORBIDRAFT_04g029190)
ZMA: 
SITA: 
ATR: 
s00006p00262750(AMTR_s00006p00262750) s00091p00092100(AMTR_s00091p00092100)
SMO: 
PPP: 
CRE: 
VCN: 
MIS: 
MPP: 
BPG: 
CSL: 
CVR: 
CME: 
GSL: 
CCP: 
EIN: 
EHE: 
DDI: 
DPP: 
DFA: 
DFA_08234(crsA)
ACAN: 
PIF: 
EHX: 
GTT: 
NGR: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Lahiri S, Park H, Laviad EL, Lu X, Bittman R, Futerman AH
  Title
Ceramide synthesis is modulated by the sphingosine analog FTY720 via a mixture of uncompetitive and noncompetitive inhibition in an Acyl-CoA chain length-dependent manner.
  Journal
J Biol Chem 284:16090-8 (2009)
Reference
  Authors
Levy M, Futerman AH
  Title
Mammalian ceramide synthases.
  Journal
IUBMB Life 62:347-56 (2010)

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