KEGG   ORTHOLOGY: K04721Help
Entry
K04721                      KO                                     

Name
TNFSF10, TRAIL, CD253
Definition
tumor necrosis factor ligand superfamily member 10
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04068  FoxO signaling pathway
ko04210  Apoptosis
ko04217  Necroptosis
ko04650  Natural killer cell mediated cytotoxicity
ko05162  Measles
ko05164  Influenza A
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04068 FoxO signaling pathway
    K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
 Cellular Processes
  Cell growth and death
   04210 Apoptosis
    K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
   04217 Necroptosis
    K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
 Human Diseases
  Infectious diseases
   05162 Measles
    K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
   05164 Influenza A
    K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
Cytokines and growth factors [BR:ko04052]
 Cytokines
  Tumor necrosis fators
   K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
CD molecules [BR:ko04090]
 Proteins
  K04721  CD253, TNFSF10; tumor necrosis factor (ligand) superfamily, member 10
BRITE hierarchy
Other DBs
GO: 0005164
Genes
HSA: 8743(TNFSF10)
PTR: 460852(TNFSF10)
PPS: 100986991(TNFSF10)
GGO: 101130096(TNFSF10)
PON: 100441526(TNFSF10)
NLE: 100579535(TNFSF10)
MCC: 694451(TNFSF10)
MCF: 101864918(TNFSF10)
CSAB: 103221246(TNFSF10)
RRO: 104657165(TNFSF10)
RBB: 108525949 108540415(TNFSF10)
CJC: 100396000(TNFSF10)
SBQ: 101030281(TNFSF10)
MMU: 22035(Tnfsf10)
RNO: 246775(Tnfsf10)
CGE: 100754968(Tnfsf10)
NGI: 103739879(Tnfsf10)
HGL: 101702439(Tnfsf10)
OCU: 100355808(TNFSF10)
TUP: 102501703(TNFSF10)
CFA: 100174780(TNFSF10)
AML: 100463573(TNFSF10)
UMR: 103676141(TNFSF10)
ORO: 101371152(TNFSF10)
FCA: 100174789(TNFSF10)
PTG: 102963342(TNFSF10)
AJU: 106990055(TNFSF10)
BTA: 507215(TNFSF10)
BOM: 102287110(TNFSF10)
BIU: 109558018(TNFSF10)
PHD: 102332806(TNFSF10)
CHX: 102173335(TNFSF10)
OAS: 101114153(TNFSF10)
SSC: 406191(TNFSF10)
CFR: 102506160(TNFSF10)
CDK: 105085942(TNFSF10)
BACU: 102997406(TNFSF10)
LVE: 103083521(TNFSF10)
OOR: 101282902(TNFSF10)
ECB: 100064377(TNFSF10)
EPZ: 103546356(TNFSF10)
EAI: 106847522(TNFSF10)
MYB: 102262545(TNFSF10)
MYD: 102751425(TNFSF10)
HAI: 109371673(TNFSF10)
RSS: 109449127(TNFSF10)
PALE: 102885663(TNFSF10)
LAV: 100659733(TNFSF10)
TMU: 101359129
MDO: 100010299(TNFSF10)
SHR: 105750042(TNFSF10)
OAA: 100074849(TNFSF10)
GGA: 378894(TNFSF10)
MGP: 100550143(TNFSF10)
CJO: 107318308(TNFSF10)
APLA: 101797713(TNFSF10)
ACYG: 106031999(TNFSF10)
GFR: 102042782(TNFSF10)
FAB: 101806118(TNFSF10)
PHI: 102100672(TNFSF10)
PMAJ: 107208991(TNFSF10)
CCW: 104688035(TNFSF10)
FPG: 101922846(TNFSF10)
FCH: 102047699(TNFSF10)
CLV: 102093335(TNFSF10)
EGZ: 104132497(TNFSF10)
AAM: 106486566(TNFSF10)
ASN: 102371031(TNFSF10)
AMJ: 102576971(TNFSF10)
PSS: 102460636(TNFSF10)
CMY: 102945208(TNFSF10)
CPIC: 101952595(TNFSF10)
ACS: 100566541(tnfsf10)
PVT: 110071293 110079056(TNFSF10)
PBI: 103056379(TNFSF10)
XLA: 100316914(tnfsf10.S) 108717006(tnfsf10.L)
XTR: 100493578(tnfsf10)
NPR: 108784823(TNFSF10)
DRE: 436866(tnfsf10)
TRU: 100653422(tnfsf10) 101061420
LCO: 104920041(tnfsf10) 104939189
OLA: 101156131(tnfsf10) 101172365
NFU: 107383107 107392066(tnfsf10)
CSEM: 103377512 103378994(tnfsf10)
LCF: 108875098(tnfsf10) 108885067 108902513(tnfsf11)
ELS: 105022065
LCM: 102345421(TNFSF10) 102347335
CMK: 103177380 103190454(tnfsf10)
SPU: 100891737
OBI: 106873185
LAK: 106155782
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8777713
  Authors
Wiley SR, Schooley K, Smolak PJ, Din WS, Huang CP, Nicholl JK, Sutherland GR, Smith TD, Rauch C, Smith CA, et al.
  Title
Identification and characterization of a new member of the TNF family that induces apoptosis.
  Journal
Immunity 3:673-82 (1995)
DOI:10.1016/1074-7613(95)90057-8
  Sequence
[hsa:8743]
Reference
  Authors
McGrath EE, Marriott HM, Lawrie A, Francis SE, Sabroe I, Renshaw SA, Dockrell DH, Whyte MK
  Title
TNF-related apoptosis-inducing ligand (TRAIL) regulates inflammatory neutrophil apoptosis and enhances resolution of inflammation.
  Journal
J Leukoc Biol 90:855-65 (2011)
DOI:10.1189/jlb.0211062
  Sequence
[mmu:22035]

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