KEGG   ORTHOLOGY: K04728Help
Entry
K04728                      KO                                     

Name
ATM, TEL1
Definition
ataxia telangiectasia mutated family protein [EC:2.7.11.1]
Pathway
NF-kappa B signaling pathway
FoxO signaling pathway
Cell cycle
p53 signaling pathway
Apoptosis
HTLV-I infection
Transcriptional misregulation in cancer
MicroRNAs in cancer
Module
M00295  
BRCA1-associated genome surveillance complex (BASC)
Disease
H00005  
Chronic lymphocytic leukemia (CLL)
H00064  
Ataxia telangiectasia (AT)
H00094  
Immunodeficiency associated with DNA repair defects
H00848  
Ataxia with ocular apraxia (AOA)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04064 NF-kappa B signaling pathway
    K04728  ATM, TEL1; ataxia telangiectasia mutated family protein
   04068 FoxO signaling pathway
    K04728  ATM, TEL1; ataxia telangiectasia mutated family protein
 Cellular Processes
  Cell growth and death
   04110 Cell cycle
    K04728  ATM, TEL1; ataxia telangiectasia mutated family protein
   04210 Apoptosis
    K04728  ATM, TEL1; ataxia telangiectasia mutated family protein
   04115 p53 signaling pathway
    K04728  ATM, TEL1; ataxia telangiectasia mutated family protein
 Human Diseases
  Cancers
   05202 Transcriptional misregulation in cancers
    K04728  ATM, TEL1; ataxia telangiectasia mutated family protein
   05206 MicroRNAs in cancer
    K04728  ATM, TEL1; ataxia telangiectasia mutated family protein
  Infectious diseases
   05166 HTLV-I infection
    K04728  ATM, TEL1; ataxia telangiectasia mutated family protein
KEGG modules [BR:ko00002]
 Structural complex
  Genetic information processing
   Repair system
    M00295  BRCA1-associated genome surveillance complex (BASC)
     K04728  ATM, TEL1; ataxia telangiectasia mutated family protein
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K04728  ATM, TEL1; ataxia telangiectasia mutated family protein
Protein kinases [BR:ko01001]
 Serine/threonine protein kinases: Atypical group
  PIKK family [OT]
   K04728  ATM, TEL1; ataxia telangiectasia mutated family protein
DNA replication proteins [BR:ko03032]
 Eukaryotic Type
  DNA Replication Termination Factors
   Other telomere regulation proteins
    K04728  ATM, TEL1; ataxia telangiectasia mutated family protein
DNA repair and recombination proteins [BR:ko03400]
 Eukaryotic Type
  Check point factors
   Other check point factors
    K04728  ATM, TEL1; ataxia telangiectasia mutated family protein
BRITE hierarchy
Genes
HSA: 
472(ATM)
PTR: 
451530(ATM)
PPS: 
GGO: 
PON: 
MCC: 
MCF: 
MMU: 
11920(Atm)
RNO: 
300711(Atm)
CGE: 
HGL: 
TUP: 
CFA: 
479450(ATM)
AML: 
FCA: 
PTG: 
BTA: 
526824(ATM)
BOM: 
PHD: 
CHX: 
SSC: 
CFR: 
BACU: 
LVE: 
ECB: 
MYB: 
MYD: 
PALE: 
MDO: 
SHR: 
OAA: 
GGA: 
395401(ATM)
MGP: 
TGU: 
FAB: 
PHI: 
APLA: 
FCH: 
CLV: 
ASN: 
AMJ: 
PSS: 
CMY: 
ACS: 
PBI: 
XLA: 
398148(atm)
XTR: 
DRE: 
403064(atm)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
BFO: 
CIN: 
SPU: 
577188(atm)
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
CQU: 
AME: 
725613(ATM)
NVI: 
TCA: 
BMOR: 
API: 
PHU: 
ISC: 
CEL: 
CBR: 
CBG22015(Cbr-atm-1)
BMY: 
SMM: 
NVE: 
HMG: 
TAD: 
AQU: 
ATH: 
ALY: 
CRB: 
EUS: 
CIT: 
CIC: 
TCC: 
GMX: 
PVU: 
MTR: 
CAM: 
FVE: 
PPER: 
CSV: 
RCU: 
POP: 
VVI: 
SLY: 
SOT: 
OSA: 
DOSA: 
Os01t0106700-00(Os01g0106700)
OBR: 
BDI: 
SBI: 
SORBI_03g008670(SORBIDRAFT_03g008670) SORBI_03g008680(SORBIDRAFT_03g008680)
SITA: 
ATR: 
s00058p00205060(AMTR_s00058p00205060) s00058p00206720(AMTR_s00058p00206720)
SMO: 
PPP: 
CRE: 
OLU: 
OTA: 
MPP: 
BPG: 
CSL: 
CVR: 
GSL: 
CCP: 
SCE: 
YBL088C(TEL1)
AGO: 
KLA: 
LTH: 
PPA: 
VPO: 
ZRO: 
CGR: 
NCS: 
NCAS_0E02450(NCAS0E02450)
NDI: 
NDAI_0E04020(NDAI0E04020)
TPF: 
TPHA_0K00690(TPHA0K00690)
TBL: 
TBLA_0D00420(TBLA0D00420)
TDL: 
TDEL_0C02790(TDEL0C02790)
KAF: 
KAFR_0L01900(KAFR0L01900)
DHA: 
PIC: 
PGU: 
LEL: 
SPAA: 
CAL: 
CTP: 
CDU: 
COT: 
CTEN: 
YLI: 
CLU: 
NCR: 
SMP: 
PAN: 
TTT: 
MTM: 
CTHR: 
MGR: 
TMN: 
FGR: 
NHE: 
TRE: 
MAW: 
MAJ: 
CMT: 
VAL: 
ELA: 
SSL: 
BFU: 
MBE: 
ANI: 
AFM: 
AOR: 
AOR_1_694094(AO090120000393)
ANG: 
ANI_1_1604124(An14g06540)
AFV: 
ACT: 
NFI: 
PCS: 
CIM: 
CPW: 
PBL: 
URE: 
ABE: 
TVE: 
AJE: 
PNO: 
PTE: 
BZE: 
ZTR: 
PFJ: 
BCOM: 
TML: 
SPO: 
CNE: 
CNB: 
CGI: 
LBC: 
MPR: 
CCI: 
SCM: 
PGR: 
MBR: 
EHI: 
EHI_017670(199.t00007)
EDI: 
ACAN: 
TGO: 
PTI: 
TPS: 
PIF: 
EHX: 
GTT: 
NGR: 
TVA: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Lavin MF, Kozlov S
  Title
ATM activation and DNA damage response.
  Journal
Cell Cycle 6:931-42 (2007)

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