KEGG   ORTHOLOGY: K04729Help
Entry
K04729                      KO                                     

Name
MYD88
Definition
myeloid differentiation primary response protein MyD88
Pathway
NF-kappa B signaling pathway
Apoptosis
Toll-like receptor signaling pathway
Salmonella infection
Pertussis
Legionellosis
Leishmaniasis
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Malaria
Toxoplasmosis
Tuberculosis
Hepatitis B
Measles
Influenza A
Herpes simplex infection
Module
M00686  
Toll-like receptor signaling
Disease
H00721  
Pyogenic bacterial infections, recurrent, due to MYD88 deficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04064 NF-kappa B signaling pathway
    K04729  MYD88; myeloid differentiation primary response protein MyD88
 Cellular Processes
  Cell growth and death
   04210 Apoptosis
    K04729  MYD88; myeloid differentiation primary response protein MyD88
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    K04729  MYD88; myeloid differentiation primary response protein MyD88
 Human Diseases
  Infectious diseases
   05132 Salmonella infection
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   05133 Pertussis
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   05134 Legionellosis
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   05152 Tuberculosis
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   05162 Measles
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   05164 Influenza A
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   05161 Hepatitis B
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   05168 Herpes simplex infection
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   05144 Malaria
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   05145 Toxoplasmosis
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   05140 Leishmaniasis
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   05142 Chagas disease (American trypanosomiasis)
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   05143 African trypanosomiasis
    K04729  MYD88; myeloid differentiation primary response protein MyD88
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00686  Toll-like receptor signaling
     K04729  MYD88; myeloid differentiation primary response protein MyD88
BRITE hierarchy
Genes
HSA: 
4615(MYD88)
PTR: 
460269(MYD88)
PPS: 
100996159(MYD88)
PON: 
100460593(MYD88)
NLE: 
100598173(MYD88)
MCC: 
696494(MYD88)
MCF: 
CJC: 
100413151(MYD88)
MMU: 
17874(Myd88)
RNO: 
301059(Myd88)
CGE: 
100775060(Myd88)
NGI: 
103744662(Myd88)
HGL: 
101712637(Myd88)
OCU: 
100340811(MYD88)
TUP: 
102499350(MYD88)
CFA: 
477024(MYD88)
AML: 
UMR: 
103680724(MYD88)
FCA: 
101087092(MYD88)
PTG: 
102952059(MYD88)
BTA: 
444881(MYD88)
BOM: 
102279944(MYD88)
PHD: 
102319871(MYD88)
CHX: 
102174883(MYD88)
OAS: 
678682(MYD88)
SSC: 
396646(MYD88)
CFR: 
102506575(MYD88)
BACU: 
103011989(MYD88)
LVE: 
103088205(MYD88)
ECB: 
100053940(MYD88)
MYB: 
102247438(MYD88)
PALE: 
102890488(MYD88)
SHR: 
100927751(MYD88)
OAA: 
100077067(MYD88)
GGA: 
420420(MYD88)
MGP: 
APLA: 
TGU: 
100223638(MYD88)
FAB: 
101805645(MYD88)
PHI: 
102100550(MYD88)
FPG: 
101922907(MYD88)
FCH: 
102049997(MYD88)
CLV: 
ASN: 
102372553(MYD88)
AMJ: 
102560312(MYD88)
PSS: 
102454616(MYD88)
CMY: 
102935478(MYD88)
ACS: 
100561767(myd88)
PBI: 
103066844(MYD88)
XLA: 
394321(myd88-a)
XTR: 
549591(myd88)
DRE: 
403145(myd88)
TRU: 
100134853(myd88)
MZE: 
OLA: 
XMA: 
LCM: 
102348650(MYD88)
CMK: 
103189851(myd88)
BFO: 
CIN: 
SPU: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
CQU: 
AME: 
413194(Myd88)
NVI: 
100118553(Myd88)
TCA: 
662213(Kra)
BMOR: 
API: 
PHU: 
ISC: 
HRO: 
LGI: 
NVE: 
AQU: 
100616081(Myd88)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9013863
  Authors
Bonnert TP, Garka KE, Parnet P, Sonoda G, Testa JR, Sims JE
  Title
The cloning and characterization of human MyD88: a member of an IL-1 receptor related family.
  Journal
FEBS Lett 402:81-4 (1997)
Reference
  Authors
Jenkins KA, Mansell A
  Title
TIR-containing adaptors in Toll-like receptor signalling.
  Journal
Cytokine 49:237-44 (2010)

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