KEGG   ORTHOLOGY: K04729Help
Entry
K04729                      KO                                     

Name
MYD88
Definition
myeloid differentiation primary response protein MyD88
Pathway
NF-kappa B signaling pathway
Toll-like receptor signaling pathway
NOD-like receptor signaling pathway
Toll and Imd signaling pathway
Salmonella infection
Pertussis
Legionellosis
Leishmaniasis
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Malaria
Toxoplasmosis
Tuberculosis
Hepatitis B
Measles
Influenza A
Herpes simplex infection
Module
M00686  
Toll-like receptor signaling
Disease
H00721  
Pyogenic bacterial infections, recurrent, due to MYD88 deficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04064 NF-kappa B signaling pathway
    K04729  MYD88; myeloid differentiation primary response protein MyD88
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   04624 Toll and Imd signaling pathway
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   04621 NOD-like receptor signaling pathway
    K04729  MYD88; myeloid differentiation primary response protein MyD88
 Human Diseases
  Infectious diseases
   05132 Salmonella infection
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   05133 Pertussis
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   05134 Legionellosis
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   05152 Tuberculosis
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   05162 Measles
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   05164 Influenza A
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   05161 Hepatitis B
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   05168 Herpes simplex infection
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   05144 Malaria
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   05145 Toxoplasmosis
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   05140 Leishmaniasis
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   05142 Chagas disease (American trypanosomiasis)
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   05143 African trypanosomiasis
    K04729  MYD88; myeloid differentiation primary response protein MyD88
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00686  Toll-like receptor signaling
     K04729  MYD88; myeloid differentiation primary response protein MyD88
BRITE hierarchy
Genes
HSA: 
4615(MYD88)
PTR: 
460269(MYD88)
PPS: 
100996159(MYD88)
PON: 
100460593(MYD88)
NLE: 
100598173(MYD88)
MCC: 
696494(MYD88)
MCF: 
101866832(MYD88)
CSAB: 
103221064(MYD88)
RRO: 
104657448(MYD88)
RBB: 
108512239(MYD88)
CJC: 
100413151(MYD88)
SBQ: 
101052794(MYD88)
MMU: 
17874(Myd88)
RNO: 
301059(Myd88)
CGE: 
100775060(Myd88)
NGI: 
103744662(Myd88)
HGL: 
101712637(Myd88)
CCAN: 
109684529(Myd88)
OCU: 
100340811(MYD88)
TUP: 
102499350(MYD88)
CFA: 
477024(MYD88)
AML: 
100479307(MYD88)
UMR: 
103680724(MYD88)
FCA: 
101087092(MYD88)
PTG: 
102952059(MYD88)
AJU: 
106966692(MYD88)
BTA: 
444881(MYD88)
BOM: 
102279944(MYD88)
BIU: 
109576356(MYD88)
PHD: 
102319871(MYD88)
CHX: 
102174883(MYD88)
OAS: 
678682(MYD88)
SSC: 
396646(MYD88)
CFR: 
102506575(MYD88)
CDK: 
105090692(MYD88)
BACU: 
103011989(MYD88)
LVE: 
103088205(MYD88)
ECB: 
100053940(MYD88)
EPZ: 
103557961(MYD88)
EAI: 
106834265(MYD88)
MYB: 
102247438(MYD88)
MYD: 
107183283(MYD88)
HAI: 
109393491(MYD88)
RSS: 
109445339(MYD88)
PALE: 
102890488(MYD88)
LAV: 
100659447(MYD88)
SHR: 
100927751(MYD88)
OAA: 
100077067(MYD88)
GGA: 
420420(MYD88)
MGP: 
100541304(MYD88)
CJO: 
107308786(MYD88)
APLA: 
ACYG: 
106036798(MYD88)
TGU: 
100223638(MYD88)
GFR: 
102044578(MYD88)
FAB: 
101805645(MYD88)
PHI: 
102100550(MYD88)
CCW: 
104686502(MYD88)
FPG: 
101922907(MYD88)
FCH: 
102049997(MYD88)
CLV: 
102087774(MYD88)
AAM: 
ASN: 
102372553(MYD88)
AMJ: 
102560312(MYD88)
PSS: 
102454616(MYD88)
CMY: 
102935478(MYD88)
CPIC: 
101944305(MYD88)
ACS: 
100561767(myd88)
PBI: 
103066844(MYD88)
GJA: 
107116437(MYD88)
XLA: 
394321(myd88.L) 734302(myd88.S)
XTR: 
549591(myd88)
NPR: 
108784626(MYD88)
DRE: 
403145(myd88)
SRX: 
SANH: 
SGH: 
IPU: 
100305041(myd88)
TRU: 
100134853(myd88)
TNG: 
LCO: 
104937116(myd88)
NCC: 
MZE: 
101476408(myd88)
OLA: 
101168580(myd88)
XMA: 
102234764(myd88)
CSEM: 
103377208(myd88)
LCF: 
108881704(myd88)
SASA: 
100169859(myd88)
ELS: 
105007691(myd88)
SFM: 
108934019(myd88)
LCM: 
102348650(MYD88)
CMK: 
103189851(myd88)
BFO: 
CIN: 
SPU: 
575081 575153(myd88)
SKO: 
100373041(myd88)
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
Dsimw501_GD10085(Dsim_GD10085)
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
CQU: 
AME: 
413194(Myd88)
BIM: 
BTER: 
SOC: 
AEC: 
ACEP: 
PBAR: 
HST: 
CFO: 
LHU: 
NVI: 
100118553(Myd88)
TCA: 
662213(Kra)
DPA: 
NVL: 
BMOR: 
DPL: 
PXY: 
API: 
DNX: 
PHU: 
DPX: 
ISC: 
TUT: 
HRO: 
LGI: 
CRG: 
105337632 105342664(Myd88-2) 105342670(Myd88)
OBI: 
LAK: 
NVE: 
ADF: 
AQU: 
100616081(Myd88)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9013863
  Authors
Bonnert TP, Garka KE, Parnet P, Sonoda G, Testa JR, Sims JE
  Title
The cloning and characterization of human MyD88: a member of an IL-1 receptor related family.
  Journal
FEBS Lett 402:81-4 (1997)
DOI:10.1016/S0014-5793(96)01506-2
  Sequence
[hsa:4615]

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