KEGG   ORTHOLOGY: K04733Help
Entry
K04733                      KO                                     

Name
IRAK4
Definition
interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
Pathway
NF-kappa B signaling pathway
Toll-like receptor signaling pathway
Neurotrophin signaling pathway
Pertussis
Leishmaniasis
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Tuberculosis
Measles
Influenza A
Module
M00686  
Toll-like receptor signaling
Disease
H00096  
Defects of toll-like receptor signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04064 NF-kappa B signaling pathway
    K04733  IRAK4; interleukin-1 receptor-associated kinase 4
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    K04733  IRAK4; interleukin-1 receptor-associated kinase 4
  Nervous system
   04722 Neurotrophin signaling pathway
    K04733  IRAK4; interleukin-1 receptor-associated kinase 4
 Human Diseases
  Infectious diseases
   05133 Pertussis
    K04733  IRAK4; interleukin-1 receptor-associated kinase 4
   05152 Tuberculosis
    K04733  IRAK4; interleukin-1 receptor-associated kinase 4
   05162 Measles
    K04733  IRAK4; interleukin-1 receptor-associated kinase 4
   05164 Influenza A
    K04733  IRAK4; interleukin-1 receptor-associated kinase 4
   05145 Toxoplasmosis
    K04733  IRAK4; interleukin-1 receptor-associated kinase 4
   05140 Leishmaniasis
    K04733  IRAK4; interleukin-1 receptor-associated kinase 4
   05142 Chagas disease (American trypanosomiasis)
    K04733  IRAK4; interleukin-1 receptor-associated kinase 4
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00686  Toll-like receptor signaling
     K04733  IRAK4; interleukin-1 receptor-associated kinase 4
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K04733  IRAK4; interleukin-1 receptor-associated kinase 4
Protein kinases [BR:ko01001]
 Serine/threonine protein kinases: TKL group
  IRAK family
   K04733  IRAK4; interleukin-1 receptor-associated kinase 4
BRITE hierarchy
Genes
HSA: 
51135(IRAK4)
PTR: 
466962(IRAK4)
PPS: 
100968191(IRAK4)
GGO: 
101141826(IRAK4)
PON: 
100447243(IRAK4)
NLE: 
100602648(IRAK4)
MCC: 
700568(IRAK4)
MCF: 
102140231(IRAK4)
RRO: 
104677388(IRAK4)
CJC: 
100402978(IRAK4)
MMU: 
266632(Irak4)
RNO: 
300177(Irak4)
CGE: 
100751891(Irak4)
NGI: 
103728592(Irak4)
HGL: 
101698190(Irak4)
OCU: 
100341605(IRAK4)
TUP: 
102490347(IRAK4)
CFA: 
486601(IRAK4)
AML: 
100469127(IRAK4)
UMR: 
103675405(IRAK4)
FCA: 
101100225(IRAK4)
PTG: 
102962570(IRAK4)
BTA: 
533692(IRAK4)
BOM: 
102284148(IRAK4)
PHD: 
102344444(IRAK4)
CHX: 
102171575(IRAK4)
OAS: 
100216438(IRAK4)
SSC: 
100127166(IRAK4)
CFR: 
102518467(IRAK4)
BACU: 
103013107(IRAK4)
LVE: 
103080704(IRAK4)
ECB: 
100054848(IRAK4)
MYB: 
102262455(IRAK4)
MYD: 
102754676(IRAK4)
PALE: 
102880867(IRAK4)
MDO: 
100019202(IRAK4)
SHR: 
100934112(IRAK4)
OAA: 
GGA: 
417796(IRAK4)
MGP: 
100538968(IRAK4)
CJO: 
107309789(IRAK4)
APLA: 
101794110(IRAK4)
TGU: 
100227974(IRAK4)
GFR: 
102032992(IRAK4)
FAB: 
101816877(IRAK4)
PHI: 
102100592(IRAK4)
CCW: 
104698327(IRAK4)
FPG: 
101914647(IRAK4)
FCH: 
102057320(IRAK4)
CLV: 
102092630(IRAK4)
AAM: 
106488895(IRAK4)
ASN: 
102375747(IRAK4)
AMJ: 
102560034(IRAK4)
PSS: 
102445433(IRAK4)
CMY: 
102940314(IRAK4)
ACS: 
100556834(irak4)
PBI: 
103053361(IRAK4)
GJA: 
107125917(IRAK4)
XTR: 
733738(irak4)
DRE: 
393132(irak4)
TRU: 
101066430(irak4)
MZE: 
101482950(irak4)
OLA: 
101158603(irak4)
XMA: 
102235789(irak4)
LCM: 
102365908(IRAK4)
CMK: 
103186122(irak4)
BFO: 
CIN: 
SPU: 
SKO: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
Dyak_GE25413(Dyak_tub)
DGR: 
DMO: 
DVI: 
Dvir_GJ22964(Dvir_tub)
MDE: 
AGA: 
AAG: 
CQU: 
SOC: 
AEC: 
HST: 
TCA: 
BMOR: 
PXY: 
API: 
PHU: 
ISC: 
HRO: 
LGI: 
CRG: 
OBI: 
TAD: 
AQU: 
ATH: 
ALY: 
CRB: 
EUS: 
BRP: 
BNA: 
THJ: 
CIT: 
CIC: 
TCC: 
GRA: 
EGR: 
GMX: 
PVU: 
VRA: 
MTR: 
CAM: 
ADU: 
AIP: 
FVE: 
PPER: 
PMUM: 
MDM: 
PXB: 
CSV: 
CMO: 
RCU: 
JCU: 
POP: 
POPTR_0008s14740g(POPTRDRAFT_803688) POPTR_0009s02580g(POPTRDRAFT_878434) POPTR_0010s10380g(POPTRDRAFT_822006) POPTR_0015s14040g(POPTRDRAFT_902524) POPTR_0160s002401
VVI: 
SLY: 
SPEN: 
SOT: 
SIND: 
BVG: 
NNU: 
OSA: 
DOSA: 
Os01t0114900-00(Os01g0114900) Os02t0681700-01(Os02g0681700) Os02t0777400-01(Os02g0777400) Os03t0170400-01(Os03g0170400) Os04t0430000-01(Os04g0430000) Os04t0616200-01(Os04g0616200) Os04t0616600-01(Os04g0616600) Os07t0262800-01(Os07g0262800) Os09t0570000-01(Os09g0570000)
OBR: 
BDI: 
SBI: 
SORBI_01g022400(SORBIDRAFT_01g022400) SORBI_01g045780(SORBIDRAFT_01g045780) SORBI_02g012390(SORBIDRAFT_02g012390) SORBI_02g022540(SORBIDRAFT_02g022540) SORBI_05g026136(SORBIDRAFT_05g026136)
ZMA: 
SITA: 
PDA: 
EGU: 
MUS: 
ATR: 
SMO: 
PPP: 
AAF: 
EHX: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Janssens S, Beyaert R
  Title
Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members.
  Journal
Mol Cell 11:293-302 (2003)

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