KEGG   ORTHOLOGY: K04733Help
Entry
K04733                      KO                                     

Name
IRAK4
Definition
interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
Pathway
NF-kappa B signaling pathway
Apoptosis
Toll-like receptor signaling pathway
Neurotrophin signaling pathway
Pertussis
Leishmaniasis
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Tuberculosis
Measles
Influenza A
Module
M00686  
Toll-like receptor signaling
Disease
H00096  
Defects of toll-like receptor signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04064 NF-kappa B signaling pathway
    K04733  IRAK4; interleukin-1 receptor-associated kinase 4
 Cellular Processes
  Cell growth and death
   04210 Apoptosis
    K04733  IRAK4; interleukin-1 receptor-associated kinase 4
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    K04733  IRAK4; interleukin-1 receptor-associated kinase 4
  Nervous system
   04722 Neurotrophin signaling pathway
    K04733  IRAK4; interleukin-1 receptor-associated kinase 4
 Human Diseases
  Infectious diseases
   05133 Pertussis
    K04733  IRAK4; interleukin-1 receptor-associated kinase 4
   05152 Tuberculosis
    K04733  IRAK4; interleukin-1 receptor-associated kinase 4
   05162 Measles
    K04733  IRAK4; interleukin-1 receptor-associated kinase 4
   05164 Influenza A
    K04733  IRAK4; interleukin-1 receptor-associated kinase 4
   05145 Toxoplasmosis
    K04733  IRAK4; interleukin-1 receptor-associated kinase 4
   05140 Leishmaniasis
    K04733  IRAK4; interleukin-1 receptor-associated kinase 4
   05142 Chagas disease (American trypanosomiasis)
    K04733  IRAK4; interleukin-1 receptor-associated kinase 4
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00686  Toll-like receptor signaling
     K04733  IRAK4; interleukin-1 receptor-associated kinase 4
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K04733  IRAK4; interleukin-1 receptor-associated kinase 4
Protein kinases [BR:ko01001]
 Serine/threonine protein kinases: TKL group
  IRAK family
   K04733  IRAK4; interleukin-1 receptor-associated kinase 4
BRITE hierarchy
Genes
HSA: 
51135(IRAK4)
PTR: 
466962(IRAK4)
PPS: 
100968191(IRAK4)
GGO: 
101141826(IRAK4)
PON: 
100447243(IRAK4)
NLE: 
100602648(IRAK4)
MCC: 
700568(IRAK4)
MCF: 
102140231(IRAK4)
CJC: 
100402978(IRAK4)
MMU: 
266632(Irak4)
RNO: 
300177(Irak4)
CGE: 
100751891(Irak4)
NGI: 
103728592(Irak4)
HGL: 
101698190(Irak4)
OCU: 
100341605(IRAK4)
TUP: 
102490347(IRAK4)
CFA: 
486601(IRAK4)
AML: 
100469127(IRAK4)
UMR: 
103675405(IRAK4)
FCA: 
101100225(IRAK4)
PTG: 
102962570(IRAK4)
BTA: 
533692(IRAK4)
BOM: 
102284148(IRAK4)
PHD: 
102344444(IRAK4)
CHX: 
102171575(IRAK4)
OAS: 
100216438(IRAK4)
SSC: 
100127166(IRAK4)
CFR: 
102518467(IRAK4)
BACU: 
103013107(IRAK4)
LVE: 
103080704(IRAK4)
ECB: 
100054848(IRAK4)
MYB: 
102262455(IRAK4)
MYD: 
102754676(IRAK4)
PALE: 
102880867(IRAK4)
MDO: 
100019202(IRAK4)
SHR: 
100934112(IRAK4)
OAA: 
GGA: 
417796(IRAK4)
MGP: 
100538968(IRAK4)
APLA: 
101794110(IRAK4)
TGU: 
100227974(IRAK4)
GFR: 
102032992(IRAK4)
FAB: 
101816877(IRAK4)
PHI: 
102100592(IRAK4)
CCW: 
104698327(IRAK4)
FPG: 
101914647(IRAK4)
FCH: 
102057320(IRAK4)
CLV: 
102092630(IRAK4)
ASN: 
102375747(IRAK4)
AMJ: 
102560034(IRAK4)
PSS: 
102445433(IRAK4)
CMY: 
102940314(IRAK4)
ACS: 
100556834(irak4)
PBI: 
103053361(IRAK4)
XTR: 
733738(irak4)
DRE: 
393132(irak4)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102365908(IRAK4)
CMK: 
103186122(irak4)
BFO: 
CIN: 
SPU: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
Dsim_GD19725(Dsim_tub)
DWI: 
DYA: 
Dyak_GE25413(Dyak_tub)
DGR: 
DMO: 
DVI: 
Dvir_GJ22964(Dvir_tub)
MDE: 
AGA: 
AAG: 
CQU: 
TCA: 
BMOR: 
API: 
PHU: 
ISC: 
HRO: 
LGI: 
TAD: 
AQU: 
ATH: 
ALY: 
CRB: 
EUS: 
BRP: 
CIT: 
CIC: 
TCC: 
EGR: 
GMX: 
PVU: 
MTR: 
CAM: 
FVE: 
PPER: 
PMUM: 
MDM: 
PXB: 
CSV: 
CMO: 
RCU: 
POP: 
POPTR_0001s032301 POPTR_0001s07320g(POPTRDRAFT_838533) POPTR_0001s07630g POPTR_0001s16810g POPTR_0001s24070g(POPTRDRAFT_706250) POPTR_0001s24720g(POPTRDRAFT_549167) POPTR_0001s43900g POPTR_0001s44740g POPTR_0001s45900g(POPTRDRAFT_1070508) POPTR_0002s16310g(POPTRDRAFT_848430) POPTR_0002s24300g(POPTRDRAFT_409532) POPTR_0003s052201 POPTR_0003s06450g(POPTRDRAFT_852947) POPTR_0003s18910g POPTR_0003s21920g POPTR_0004s01450g POPTR_0004s024002 POPTR_0004s02420g POPTR_0004s02460g POPTR_0004s02490g(POPTRDRAFT_857232) POPTR_0004s02800g POPTR_0004s06240g(POPTRDRAFT_197470) POPTR_0004s06270g POPTR_0004s18580g POPTR_0004s20370g POPTR_0005s01810g POPTR_0005s058402 POPTR_0006s13040g POPTR_0006s18780g POPTR_0006s25940g(POPTRDRAFT_867573) POPTR_0006s26880g(POPTRDRAFT_561881) POPTR_0007s00780g(POPTRDRAFT_216168) POPTR_0007s00820g(POPTRDRAFT_871803) POPTR_0007s02250g POPTR_0007s03090g(POPTRDRAFT_216166) POPTR_0008s04050g(POPTRDRAFT_873439) POPTR_0008s05650g(POPTRDRAFT_720623) POPTR_0008s14520g POPTR_0008s14740g(POPTRDRAFT_803688) POPTR_0009s02580g(POPTRDRAFT_878434) POPTR_0009s03160g(POPTRDRAFT_203912) POPTR_0009s03660g(POPTRDRAFT_768202) POPTR_0009s15900g(POPTRDRAFT_556874) POPTR_0010s10380g(POPTRDRAFT_822006) POPTR_0010s10590g(POPTRDRAFT_1090474) POPTR_0010s13080g(POPTRDRAFT_225382) POPTR_0010s21090g(POPTRDRAFT_805513) POPTR_0010s22820g(POPTRDRAFT_880638) POPTR_0010s23180g(POPTRDRAFT_883337) POPTR_0011s02130g POPTR_0011s021802 POPTR_0011s03210g POPTR_0011s03330g(POPTRDRAFT_568394) POPTR_0011s036301 POPTR_0011s04930g POPTR_0011s06100g POPTR_0011s06110g POPTR_0011s06150g POPTR_0011s06170g POPTR_0011s062402 POPTR_0011s065502 POPTR_0011s06595g POPTR_0011s06650g POPTR_0011s080251 POPTR_0011s12900g POPTR_0011s13070g POPTR_0011s13090g POPTR_0011s15020g(POPTRDRAFT_232789) POPTR_0012s00850g POPTR_0012s00870g POPTR_0012s00880g POPTR_0012s05080g(POPTRDRAFT_422346) POPTR_0012s05090g(POPTRDRAFT_772678) POPTR_0012s05180g(POPTRDRAFT_1095252) POPTR_0013s02080g(POPTRDRAFT_806787) POPTR_0013s08930g(POPTRDRAFT_571599) POPTR_0014s13210g(POPTRDRAFT_572780) POPTR_0014s14570g POPTR_0015s09350g(POPTRDRAFT_1101409) POPTR_0016s11410g POPTR_0016s12220g(POPTRDRAFT_825335) POPTR_0017s01210g POPTR_0017s04120g POPTR_0017s06330g POPTR_0017s090701 POPTR_0017s091401 POPTR_0017s09230g POPTR_0017s09520g POPTR_0017s10040g POPTR_0018s13280g(POPTRDRAFT_259726) POPTR_0018s13370g(POPTRDRAFT_912083) POPTR_0019s01880g POPTR_0019s12420g POPTR_0019s14230g POPTR_0021s00680g POPTR_0021s00700g POPTR_0053s00220g POPTR_0073s00200g POPTR_0075s00200g POPTR_0075s00220g POPTR_0104s00230g POPTR_0107s002301 POPTR_0107s00280g POPTR_0118s00240g POPTR_0118s00250g POPTR_0138s002301 POPTR_0138s002303 POPTR_0144s00230g POPTR_0197s00200g POPTR_0197s00240g POPTR_0294s002001 POPTR_0309s002001 POPTR_0316s00220g POPTR_0518s002001 POPTR_0728s00200g POPTR_0806s00200g POPTR_1009s00200g POPTR_1037s00200g POPTR_1224s00200g POPTR_1247s002002 POPTR_1276s002002 POPTR_1560s00200g POPTR_2039s002002
VVI: 
SLY: 
SOT: 
BVG: 
OSA: 
DOSA: 
Os01t0114400-00(Os01g0114400) Os01t0117100-00(Os01g0117100) Os01t0117300-00(Os01g0117300) Os01t0568800-00(Os01g0568800) Os01t0648600-00(Os01g0648600) Os01t0819100-01(Os01g0819100) Os01t0870500-01(Os01g0870500) Os01t0890100-00(Os01g0890100) Os02t0218600-00(Os02g0218600) Os02t0472700-00(Os02g0472700) Os02t0553000-01(Os02g0553000) Os03t0170400-01(Os03g0170400) Os04t0658700-00(Os04g0658700) Os05t0110900-01(Os05g0110900) Os05t0231100-00(Os05g0231100) Os06t0575000-00(Os06g0575000) Os07t0248600-00(Os07g0248600) Os07t0301500-00(Os07g0301500) Os08t0179000-01(Os08g0179000) Os08t0378300-00(Os08g0378300) Os09t0349100-00(Os09g0349100) Os10t0103140-00(Os10g0103140) Os10t0326200-00(Os10g0326200) Os11t0226201-00(Os11g0226201)
OBR: 
BDI: 
SBI: 
SORBI_01g019010(SORBIDRAFT_01g019010) SORBI_01g022400(SORBIDRAFT_01g022400) SORBI_01g023180(SORBIDRAFT_01g023180) SORBI_01g033855(SORBIDRAFT_01g033855) SORBI_01g038833(SORBIDRAFT_01g038833) SORBI_01g045780(SORBIDRAFT_01g045780) SORBI_02g021570(SORBIDRAFT_02g021570) SORBI_02g023540(SORBIDRAFT_02g023540) SORBI_03g002425(SORBIDRAFT_03g002425) SORBI_03g007390(SORBIDRAFT_03g007390) SORBI_03g008430(SORBIDRAFT_03g008430) SORBI_03g025610(SORBIDRAFT_03g025610) SORBI_03g029550(SORBIDRAFT_03g029550) SORBI_04g003073(SORBIDRAFT_04g003073) SORBI_04g007520(SORBIDRAFT_04g007520) SORBI_05g005345(SORBIDRAFT_05g005345) SORBI_05g008260(SORBIDRAFT_05g008260) SORBI_05g026136(SORBIDRAFT_05g026136) SORBI_05g026185(SORBIDRAFT_05g026185) SORBI_06g002190(SORBIDRAFT_06g002190) SORBI_06g021790(SORBIDRAFT_06g021790) SORBI_06g029810(SORBIDRAFT_06g029810) SORBI_06g031420(SORBIDRAFT_06g031420) SORBI_09g000220(SORBIDRAFT_09g000220) SORBI_09g001190(SORBIDRAFT_09g001190) SORBI_09g001746(SORBIDRAFT_09g001746) SORBI_09g005195(SORBIDRAFT_09g005195) SORBI_10g013500(SORBIDRAFT_10g013500) SORBI_10g022070(SORBIDRAFT_10g022070) SORBI_10g026050(SORBIDRAFT_10g026050)
ZMA: 
SITA: 
PDA: 
MUS: 
ATR: 
s00002p00258680(AMTR_s00002p00258680) s00009p00113190(AMTR_s00009p00113190) s00009p00267490(AMTR_s00009p00267490) s00010p00251210(AMTR_s00010p00251210) s00010p00251410(AMTR_s00010p00251410) s00012p00221000(AMTR_s00012p00221000) s00016p00199290(AMTR_s00016p00199290) s00016p00235240(AMTR_s00016p00235240) s00019p00191440(AMTR_s00019p00191440) s00019p00229850(AMTR_s00019p00229850) s00019p00230170(AMTR_s00019p00230170) s00024p00153540(AMTR_s00024p00153540) s00025p00106480(AMTR_s00025p00106480) s00027p00225540(AMTR_s00027p00225540) s00035p00086470(AMTR_s00035p00086470) s00044p00167070(AMTR_s00044p00167070) s00056p00191650(AMTR_s00056p00191650) s00056p00203120(AMTR_s00056p00203120) s00059p00161310(AMTR_s00059p00161310) s00062p00107880(AMTR_s00062p00107880) s00070p00160180(AMTR_s00070p00160180) s00075p00012310(AMTR_s00075p00012310) s00079p00195720(AMTR_s00079p00195720) s00092p00128890(AMTR_s00092p00128890) s00095p00164150(AMTR_s00095p00164150) s00101p00091150(AMTR_s00101p00091150) s00106p00032210(AMTR_s00106p00032210) s00106p00036370(AMTR_s00106p00036370) s00106p00037170(AMTR_s00106p00037170) s00130p00078720(AMTR_s00130p00078720) s00146p00101260(AMTR_s00146p00101260) s00162p00056910(AMTR_s00162p00056910) s00162p00057050(AMTR_s00162p00057050) s00171p00046350(AMTR_s00171p00046350) s00175p00044500(AMTR_s00175p00044500) s00213p00028200(AMTR_s00213p00028200) s00213p00032300(AMTR_s00213p00032300) s01480p00009240(AMTR_s01480p00009240)
SMO: 
SELMODRAFT_101095 SELMODRAFT_103068 SELMODRAFT_103947 SELMODRAFT_103981 SELMODRAFT_105326 SELMODRAFT_105487 SELMODRAFT_106165 SELMODRAFT_106383 SELMODRAFT_108156 SELMODRAFT_108379 SELMODRAFT_108868 SELMODRAFT_111086 SELMODRAFT_111388 SELMODRAFT_112637 SELMODRAFT_112967 SELMODRAFT_113945 SELMODRAFT_114843 SELMODRAFT_116570 SELMODRAFT_118274 SELMODRAFT_119488 SELMODRAFT_119669 SELMODRAFT_120844 SELMODRAFT_121148 SELMODRAFT_121956 SELMODRAFT_122254 SELMODRAFT_124183 SELMODRAFT_124924 SELMODRAFT_126642 SELMODRAFT_128334 SELMODRAFT_129564 SELMODRAFT_13113 SELMODRAFT_131134 SELMODRAFT_131586 SELMODRAFT_131658 SELMODRAFT_132357 SELMODRAFT_133410 SELMODRAFT_134861 SELMODRAFT_135372 SELMODRAFT_135779 SELMODRAFT_13751 SELMODRAFT_13832 SELMODRAFT_13833 SELMODRAFT_138704 SELMODRAFT_14061 SELMODRAFT_14192 SELMODRAFT_142218 SELMODRAFT_142337 SELMODRAFT_14302 SELMODRAFT_14347 SELMODRAFT_145055 SELMODRAFT_145920 SELMODRAFT_149289 SELMODRAFT_153168 SELMODRAFT_15419 SELMODRAFT_15884 SELMODRAFT_159261 SELMODRAFT_16360 SELMODRAFT_164191 SELMODRAFT_17425 SELMODRAFT_17456 SELMODRAFT_17508 SELMODRAFT_17510 SELMODRAFT_17512 SELMODRAFT_17519 SELMODRAFT_17521 SELMODRAFT_17523 SELMODRAFT_17546 SELMODRAFT_17547 SELMODRAFT_17548 SELMODRAFT_175908 SELMODRAFT_176397 SELMODRAFT_180094 SELMODRAFT_230241 SELMODRAFT_23109 SELMODRAFT_23584 SELMODRAFT_23585 SELMODRAFT_236934 SELMODRAFT_2406 SELMODRAFT_24639 SELMODRAFT_24896 SELMODRAFT_25022 SELMODRAFT_25383 SELMODRAFT_25384 SELMODRAFT_25489 SELMODRAFT_25647 SELMODRAFT_27379 SELMODRAFT_27666 SELMODRAFT_27719 SELMODRAFT_3146 SELMODRAFT_31805 SELMODRAFT_31809 SELMODRAFT_31869 SELMODRAFT_33560 SELMODRAFT_33807 SELMODRAFT_33809 SELMODRAFT_34595 SELMODRAFT_35175 SELMODRAFT_35365 SELMODRAFT_37866 SELMODRAFT_403966 SELMODRAFT_408118 SELMODRAFT_41669 SELMODRAFT_41780 SELMODRAFT_444390 SELMODRAFT_45064 SELMODRAFT_54423 SELMODRAFT_54460 SELMODRAFT_55105 SELMODRAFT_55221 SELMODRAFT_61771 SELMODRAFT_6328 SELMODRAFT_6355 SELMODRAFT_64706 SELMODRAFT_65009 SELMODRAFT_65208 SELMODRAFT_66995 SELMODRAFT_72610 SELMODRAFT_72626 SELMODRAFT_74182 SELMODRAFT_75689 SELMODRAFT_7775 SELMODRAFT_78793 SELMODRAFT_81540 SELMODRAFT_82517 SELMODRAFT_85468 SELMODRAFT_86219 SELMODRAFT_88672 SELMODRAFT_90825 SELMODRAFT_92161 SELMODRAFT_93421 SELMODRAFT_97344 SELMODRAFT_98860 SELMODRAFT_99517 SELMODRAFT_99707
PPP: 
CRE: 
VCN: 
EHX: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Janssens S, Beyaert R
  Title
Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members.
  Journal
Mol Cell 11:293-302 (2003)

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