KEGG   ORTHOLOGY: K04733Help
Entry
K04733                      KO                                     

Name
IRAK4
Definition
interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
Pathway
NF-kappa B signaling pathway
Apoptosis
Toll-like receptor signaling pathway
Neurotrophin signaling pathway
Pertussis
Leishmaniasis
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Tuberculosis
Measles
Influenza A
Disease
H00096  
Defects of toll-like receptor signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04064 NF-kappa B signaling pathway
    K04733  IRAK4; interleukin-1 receptor-associated kinase 4
 Cellular Processes
  Cell growth and death
   04210 Apoptosis
    K04733  IRAK4; interleukin-1 receptor-associated kinase 4
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    K04733  IRAK4; interleukin-1 receptor-associated kinase 4
  Nervous system
   04722 Neurotrophin signaling pathway
    K04733  IRAK4; interleukin-1 receptor-associated kinase 4
 Human Diseases
  Infectious diseases
   05133 Pertussis
    K04733  IRAK4; interleukin-1 receptor-associated kinase 4
   05152 Tuberculosis
    K04733  IRAK4; interleukin-1 receptor-associated kinase 4
   05162 Measles
    K04733  IRAK4; interleukin-1 receptor-associated kinase 4
   05164 Influenza A
    K04733  IRAK4; interleukin-1 receptor-associated kinase 4
   05145 Toxoplasmosis
    K04733  IRAK4; interleukin-1 receptor-associated kinase 4
   05140 Leishmaniasis
    K04733  IRAK4; interleukin-1 receptor-associated kinase 4
   05142 Chagas disease (American trypanosomiasis)
    K04733  IRAK4; interleukin-1 receptor-associated kinase 4
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K04733  IRAK4; interleukin-1 receptor-associated kinase 4
Protein kinases [BR:ko01001]
 Serine/threonine protein kinases: TKL group
  IRAK family
   K04733  IRAK4; interleukin-1 receptor-associated kinase 4
BRITE hierarchy
Genes
HSA: 
51135(IRAK4)
PTR: 
466962(IRAK4)
PPS: 
100968191(IRAK4)
GGO: 
101141826(IRAK4)
PON: 
100447243(IRAK4)
MCC: 
700568(IRAK4)
MCF: 
102140231(IRAK4)
MMU: 
266632(Irak4)
RNO: 
300177(Irak4)
CGE: 
100751891(Irak4)
HGL: 
101698190(Irak4)
TUP: 
102490347(IRAK4)
CFA: 
486601(IRAK4)
AML: 
100469127(IRAK4)
FCA: 
101100225(IRAK4)
PTG: 
102962570(IRAK4)
BTA: 
533692(IRAK4)
BOM: 
102284148(IRAK4)
PHD: 
102344444(IRAK4)
CHX: 
102171575(IRAK4)
SSC: 
100127166(IRAK4)
CFR: 
102518467(IRAK4)
BACU: 
103013107(IRAK4)
LVE: 
103080704(IRAK4)
ECB: 
100054848(IRAK4)
MYB: 
102262455(IRAK4)
MYD: 
102754676(IRAK4)
PALE: 
102880867(IRAK4)
MDO: 
100019202(IRAK4)
SHR: 
100934112(IRAK4)
OAA: 
GGA: 
417796(IRAK4)
MGP: 
TGU: 
100227974(IRAK4)
FAB: 
101816877(IRAK4)
PHI: 
102100592(IRAK4)
APLA: 
101794110(IRAK4)
FPG: 
101914647(IRAK4)
FCH: 
102057320(IRAK4)
CLV: 
102092630(IRAK4)
ASN: 
102375747(IRAK4)
AMJ: 
102560034(IRAK4)
PSS: 
102445433(IRAK4)
CMY: 
102940314(IRAK4)
ACS: 
PBI: 
103053361(IRAK4)
XTR: 
733738(irak4)
DRE: 
393132(irak4)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102365908(IRAK4)
CMK: 
103186122(irak4)
BFO: 
CIN: 
SPU: 
AGA: 
AAG: 
CQU: 
BMOR: 
API: 
PHU: 
ISC: 
TAD: 
AQU: 
ATH: 
ALY: 
CRB: 
EUS: 
CIT: 
CIC: 
TCC: 
GMX: 
PVU: 
MTR: 
CAM: 
FVE: 
PPER: 
CSV: 
RCU: 
POP: 
POPTR_0001s07320g(POPTRDRAFT_838533) POPTR_0001s16810g POPTR_0001s24720g(POPTRDRAFT_549167) POPTR_0001s28330g(POPTRDRAFT_706543) POPTR_0001s43240g POPTR_0001s43900g POPTR_0001s44740g POPTR_0002s16310g(POPTRDRAFT_848430) POPTR_0002s24300g(POPTRDRAFT_409532) POPTR_0003s052201 POPTR_0003s06450g(POPTRDRAFT_852947) POPTR_0003s18470g POPTR_0003s18910g POPTR_0003s21920g POPTR_0004s01450g POPTR_0004s02370g(POPTRDRAFT_857728) POPTR_0004s02420g POPTR_0004s02800g POPTR_0004s06240g(POPTRDRAFT_197470) POPTR_0004s06270g POPTR_0004s18580g POPTR_0004s20370g POPTR_0005s01810g POPTR_0005s04200g POPTR_0005s11010g POPTR_0005s20780g POPTR_0006s07070g(POPTRDRAFT_415691) POPTR_0006s13040g POPTR_0006s18780g POPTR_0006s25940g(POPTRDRAFT_867573) POPTR_0006s26880g(POPTRDRAFT_561881) POPTR_0007s00780g(POPTRDRAFT_216168) POPTR_0007s00820g(POPTRDRAFT_871803) POPTR_0007s02250g POPTR_0007s03090g(POPTRDRAFT_216166) POPTR_0008s05650g(POPTRDRAFT_720623) POPTR_0008s14740g(POPTRDRAFT_803688) POPTR_0009s02580g(POPTRDRAFT_878434) POPTR_0009s03160g(POPTRDRAFT_203912) POPTR_0009s03660g(POPTRDRAFT_768202) POPTR_0009s14230g(POPTRDRAFT_200551) POPTR_0009s15900g(POPTRDRAFT_556874) POPTR_0010s00390g(POPTRDRAFT_228910) POPTR_0010s10380g(POPTRDRAFT_822006) POPTR_0010s11990g(POPTRDRAFT_231820) POPTR_0010s13080g(POPTRDRAFT_225382) POPTR_0010s21090g(POPTRDRAFT_805513) POPTR_0010s22820g(POPTRDRAFT_880638) POPTR_0010s23180g(POPTRDRAFT_883337) POPTR_0011s02130g POPTR_0011s021702 POPTR_0011s021802 POPTR_0011s03330g(POPTRDRAFT_568394) POPTR_0011s036301 POPTR_0011s03710g POPTR_0011s04930g POPTR_0011s06100g POPTR_0011s06110g POPTR_0011s06170g POPTR_0011s062402 POPTR_0011s065502 POPTR_0011s06650g POPTR_0011s080251 POPTR_0011s12900g POPTR_0011s13080g POPTR_0011s13090g POPTR_0012s00850g POPTR_0012s00880g POPTR_0012s05090g(POPTRDRAFT_772678) POPTR_0012s05180g(POPTRDRAFT_1095252) POPTR_0013s02080g(POPTRDRAFT_806787) POPTR_0013s08930g(POPTRDRAFT_571599) POPTR_0014s13210g(POPTRDRAFT_572780) POPTR_0014s13990g(POPTRDRAFT_246260) POPTR_0015s00230g POPTR_0016s03110g(POPTRDRAFT_576114) POPTR_0016s11410g POPTR_0016s12220g(POPTRDRAFT_825335) POPTR_0017s00750g POPTR_0017s01210g POPTR_0017s03640g POPTR_0017s03655g POPTR_0017s03820g POPTR_0017s04040g(POPTRDRAFT_577282) POPTR_0017s04080g POPTR_0017s04100g POPTR_0017s04120g POPTR_0017s04140g POPTR_0017s04160g POPTR_0017s04180g POPTR_0017s06330g POPTR_0017s091401 POPTR_0017s09520g POPTR_0018s13280g(POPTRDRAFT_259726) POPTR_0018s13370g(POPTRDRAFT_912083) POPTR_0018s13550g POPTR_0019s01880g POPTR_0019s12420g POPTR_0019s14230g POPTR_0021s00680g POPTR_0021s00700g POPTR_0021s01050g POPTR_0053s00220g POPTR_0073s00200g POPTR_0104s00230g POPTR_0107s002301 POPTR_0107s00280g POPTR_0112s00220g POPTR_0118s00240g POPTR_0118s00250g POPTR_0138s002301 POPTR_0138s002303 POPTR_0144s00230g POPTR_0247s00220g POPTR_0294s002001 POPTR_0316s00220g POPTR_0518s002001 POPTR_0806s00200g POPTR_1009s00200g POPTR_1224s00200g POPTR_1247s002002 POPTR_1276s002002 POPTR_1560s00200g POPTR_2039s002002
VVI: 
SLY: 
SOT: 
OSA: 
DOSA: 
Os01t0114400-00(Os01g0114400) Os01t0819100-01(Os01g0819100) Os01t0890100-00(Os01g0890100) Os02t0639100-00(Os02g0639100) Os03t0170400-01(Os03g0170400) Os04t0369066-00(Os04g0369066) Os04t0658700-00(Os04g0658700) Os05t0110900-01(Os05g0110900) Os05t0231100-00(Os05g0231100) Os07t0248600-00(Os07g0248600) Os07t0301500-00(Os07g0301500) Os08t0179000-01(Os08g0179000) Os09t0349100-00(Os09g0349100) Os10t0103140-00(Os10g0103140) Os10t0116600-00(Os10g0116600) Os11t0549300-00(Os11g0549300)
OBR: 
BDI: 
SBI: 
SORBI_01g017410(SORBIDRAFT_01g017410) SORBI_01g019010(SORBIDRAFT_01g019010) SORBI_01g022400(SORBIDRAFT_01g022400) SORBI_01g023180(SORBIDRAFT_01g023180) SORBI_01g033855(SORBIDRAFT_01g033855) SORBI_01g038833(SORBIDRAFT_01g038833) SORBI_01g045780(SORBIDRAFT_01g045780) SORBI_02g021570(SORBIDRAFT_02g021570) SORBI_03g002425(SORBIDRAFT_03g002425) SORBI_03g007390(SORBIDRAFT_03g007390) SORBI_03g008430(SORBIDRAFT_03g008430) SORBI_04g002520(SORBIDRAFT_04g002520) SORBI_04g003073(SORBIDRAFT_04g003073) SORBI_04g007520(SORBIDRAFT_04g007520) SORBI_05g005185(SORBIDRAFT_05g005185) SORBI_05g005345(SORBIDRAFT_05g005345) SORBI_05g008260(SORBIDRAFT_05g008260) SORBI_05g008300(SORBIDRAFT_05g008300) SORBI_05g026136(SORBIDRAFT_05g026136) SORBI_05g026185(SORBIDRAFT_05g026185) SORBI_06g002190(SORBIDRAFT_06g002190) SORBI_06g029810(SORBIDRAFT_06g029810) SORBI_06g031420(SORBIDRAFT_06g031420) SORBI_07g025590(SORBIDRAFT_07g025590) SORBI_09g000220(SORBIDRAFT_09g000220) SORBI_09g001190(SORBIDRAFT_09g001190) SORBI_09g001746(SORBIDRAFT_09g001746) SORBI_09g005195(SORBIDRAFT_09g005195) SORBI_10g022070(SORBIDRAFT_10g022070) SORBI_10g026050(SORBIDRAFT_10g026050)
ZMA: 
SITA: 
ATR: 
s00008p00241640(AMTR_s00008p00241640) s00009p00113190(AMTR_s00009p00113190) s00009p00267490(AMTR_s00009p00267490) s00010p00251210(AMTR_s00010p00251210) s00010p00251410(AMTR_s00010p00251410) s00012p00145480(AMTR_s00012p00145480) s00012p00221000(AMTR_s00012p00221000) s00012p00255170(AMTR_s00012p00255170) s00014p00249190(AMTR_s00014p00249190) s00016p00199290(AMTR_s00016p00199290) s00019p00191440(AMTR_s00019p00191440) s00025p00106480(AMTR_s00025p00106480) s00027p00225540(AMTR_s00027p00225540) s00029p00237920(AMTR_s00029p00237920) s00035p00086470(AMTR_s00035p00086470) s00044p00167070(AMTR_s00044p00167070) s00056p00191650(AMTR_s00056p00191650) s00062p00107880(AMTR_s00062p00107880) s00070p00160180(AMTR_s00070p00160180) s00075p00012310(AMTR_s00075p00012310) s00079p00150100(AMTR_s00079p00150100) s00085p00115570(AMTR_s00085p00115570) s00092p00128890(AMTR_s00092p00128890) s00095p00164150(AMTR_s00095p00164150) s00101p00091150(AMTR_s00101p00091150) s00106p00036370(AMTR_s00106p00036370) s00117p00125350(AMTR_s00117p00125350) s00130p00078720(AMTR_s00130p00078720) s00162p00056910(AMTR_s00162p00056910) s00162p00057050(AMTR_s00162p00057050) s00171p00046350(AMTR_s00171p00046350) s00175p00044500(AMTR_s00175p00044500) s00213p00032300(AMTR_s00213p00032300)
SMO: 
SELMODRAFT_101095 SELMODRAFT_103068 SELMODRAFT_103947 SELMODRAFT_103981 SELMODRAFT_104776 SELMODRAFT_105326 SELMODRAFT_105487 SELMODRAFT_106165 SELMODRAFT_106383 SELMODRAFT_108156 SELMODRAFT_108868 SELMODRAFT_111086 SELMODRAFT_111388 SELMODRAFT_112637 SELMODRAFT_112967 SELMODRAFT_113945 SELMODRAFT_114843 SELMODRAFT_116570 SELMODRAFT_119488 SELMODRAFT_119669 SELMODRAFT_121148 SELMODRAFT_122254 SELMODRAFT_124183 SELMODRAFT_124924 SELMODRAFT_125579 SELMODRAFT_126642 SELMODRAFT_128334 SELMODRAFT_129564 SELMODRAFT_13113 SELMODRAFT_131134 SELMODRAFT_131152 SELMODRAFT_131164 SELMODRAFT_131586 SELMODRAFT_133410 SELMODRAFT_13423 SELMODRAFT_134626 SELMODRAFT_134861 SELMODRAFT_135372 SELMODRAFT_135439 SELMODRAFT_135779 SELMODRAFT_136607 SELMODRAFT_13751 SELMODRAFT_13832 SELMODRAFT_13833 SELMODRAFT_138704 SELMODRAFT_13923 SELMODRAFT_13924 SELMODRAFT_14061 SELMODRAFT_14192 SELMODRAFT_142337 SELMODRAFT_142471 SELMODRAFT_14302 SELMODRAFT_14347 SELMODRAFT_145055 SELMODRAFT_145920 SELMODRAFT_149289 SELMODRAFT_153168 SELMODRAFT_15419 SELMODRAFT_15884 SELMODRAFT_159261 SELMODRAFT_162409 SELMODRAFT_16308 SELMODRAFT_16360 SELMODRAFT_17443 SELMODRAFT_17456 SELMODRAFT_17508 SELMODRAFT_17512 SELMODRAFT_17519 SELMODRAFT_17521 SELMODRAFT_17523 SELMODRAFT_17546 SELMODRAFT_17547 SELMODRAFT_17548 SELMODRAFT_175908 SELMODRAFT_176397 SELMODRAFT_180094 SELMODRAFT_230241 SELMODRAFT_23109 SELMODRAFT_23584 SELMODRAFT_23585 SELMODRAFT_236934 SELMODRAFT_2406 SELMODRAFT_24639 SELMODRAFT_24883 SELMODRAFT_24884 SELMODRAFT_24896 SELMODRAFT_25022 SELMODRAFT_25383 SELMODRAFT_25384 SELMODRAFT_25482 SELMODRAFT_25489 SELMODRAFT_25647 SELMODRAFT_27379 SELMODRAFT_27666 SELMODRAFT_27719 SELMODRAFT_27749 SELMODRAFT_3146 SELMODRAFT_31805 SELMODRAFT_31809 SELMODRAFT_31869 SELMODRAFT_33560 SELMODRAFT_33807 SELMODRAFT_33809 SELMODRAFT_34595 SELMODRAFT_35175 SELMODRAFT_37866 SELMODRAFT_403966 SELMODRAFT_444390 SELMODRAFT_45064 SELMODRAFT_54423 SELMODRAFT_54460 SELMODRAFT_55105 SELMODRAFT_55180 SELMODRAFT_55221 SELMODRAFT_56508 SELMODRAFT_56703 SELMODRAFT_6328 SELMODRAFT_6355 SELMODRAFT_64103 SELMODRAFT_64706 SELMODRAFT_65009 SELMODRAFT_65208 SELMODRAFT_66995 SELMODRAFT_74182 SELMODRAFT_75689 SELMODRAFT_7775 SELMODRAFT_78793 SELMODRAFT_79019 SELMODRAFT_81540 SELMODRAFT_81865 SELMODRAFT_82517 SELMODRAFT_84378 SELMODRAFT_85468 SELMODRAFT_88369 SELMODRAFT_88672 SELMODRAFT_89279 SELMODRAFT_90673 SELMODRAFT_90825 SELMODRAFT_93421 SELMODRAFT_97344 SELMODRAFT_98860 SELMODRAFT_99517 SELMODRAFT_99707
PPP: 
PHYPADRAFT_102090 PHYPADRAFT_111171 PHYPADRAFT_111615 PHYPADRAFT_112554 PHYPADRAFT_113034 PHYPADRAFT_115088 PHYPADRAFT_115277 PHYPADRAFT_115668 PHYPADRAFT_117008 PHYPADRAFT_117712 PHYPADRAFT_117930 PHYPADRAFT_118054 PHYPADRAFT_118782 PHYPADRAFT_119705 PHYPADRAFT_120764 PHYPADRAFT_121481 PHYPADRAFT_121923 PHYPADRAFT_121988 PHYPADRAFT_124326 PHYPADRAFT_124666 PHYPADRAFT_124677 PHYPADRAFT_125216 PHYPADRAFT_125290 PHYPADRAFT_126477 PHYPADRAFT_126911 PHYPADRAFT_128213 PHYPADRAFT_128239 PHYPADRAFT_128521 PHYPADRAFT_129424 PHYPADRAFT_131181 PHYPADRAFT_131412 PHYPADRAFT_132548 PHYPADRAFT_132817 PHYPADRAFT_134844 PHYPADRAFT_135249 PHYPADRAFT_135864 PHYPADRAFT_136968 PHYPADRAFT_137696 PHYPADRAFT_138654 PHYPADRAFT_138749 PHYPADRAFT_139759 PHYPADRAFT_141229 PHYPADRAFT_141265 PHYPADRAFT_141299 PHYPADRAFT_142591 PHYPADRAFT_14536 PHYPADRAFT_145861 PHYPADRAFT_146336 PHYPADRAFT_146583 PHYPADRAFT_147512 PHYPADRAFT_147657 PHYPADRAFT_14792 PHYPADRAFT_14799 PHYPADRAFT_150190 PHYPADRAFT_150397 PHYPADRAFT_152199 PHYPADRAFT_15545 PHYPADRAFT_157257 PHYPADRAFT_15768 PHYPADRAFT_161314 PHYPADRAFT_16220 PHYPADRAFT_16691 PHYPADRAFT_172520 PHYPADRAFT_184270 PHYPADRAFT_185852 PHYPADRAFT_186719 PHYPADRAFT_187298 PHYPADRAFT_188184 PHYPADRAFT_193977 PHYPADRAFT_204605 PHYPADRAFT_216841 PHYPADRAFT_218598 PHYPADRAFT_221112 PHYPADRAFT_230733 PHYPADRAFT_24208 PHYPADRAFT_24285 PHYPADRAFT_24621 PHYPADRAFT_30748 PHYPADRAFT_31891 PHYPADRAFT_32703 PHYPADRAFT_32853 PHYPADRAFT_34014 PHYPADRAFT_34265 PHYPADRAFT_3862 PHYPADRAFT_41108 PHYPADRAFT_41193 PHYPADRAFT_4246 PHYPADRAFT_43124 PHYPADRAFT_43847 PHYPADRAFT_44271 PHYPADRAFT_44356 PHYPADRAFT_44440 PHYPADRAFT_44470 PHYPADRAFT_44529 PHYPADRAFT_44647 PHYPADRAFT_44714 PHYPADRAFT_44939 PHYPADRAFT_45260 PHYPADRAFT_45433 PHYPADRAFT_50802 PHYPADRAFT_51429 PHYPADRAFT_5170 PHYPADRAFT_56753 PHYPADRAFT_75743 PHYPADRAFT_88342 PHYPADRAFT_94070
CRE: 
VCN: 
EHX: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Janssens S, Beyaert R
  Title
Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members.
  Journal
Mol Cell 11:293-302 (2003)

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