KEGG   ORTHOLOGY: K04734Help
Entry
K04734                      KO                                     

Name
NFKBIA
Definition
NF-kappa-B inhibitor alpha
Pathway
cAMP signaling pathway
Chemokine signaling pathway
NF-kappa B signaling pathway
Apoptosis
Osteoclast differentiation
Toll-like receptor signaling pathway
NOD-like receptor signaling pathway
RIG-I-like receptor signaling pathway
Cytosolic DNA-sensing pathway
T cell receptor signaling pathway
B cell receptor signaling pathway
TNF signaling pathway
Neurotrophin signaling pathway
Adipocytokine signaling pathway
Insulin resistance
Epithelial cell signaling in Helicobacter pylori infection
Shigellosis
Legionellosis
Leishmaniasis
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Herpes simplex infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Prostate cancer
Chronic myeloid leukemia
Small cell lung cancer
Module
M00686  
Toll-like receptor signaling
Disease
H00007  
Hodgkin lymphoma
H00095  
Ectodermal dysplasia associated immunodeficiency (EDA-ID)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04064 NF-kappa B signaling pathway
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   04668 TNF signaling pathway
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   04024 cAMP signaling pathway
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
 Cellular Processes
  Cell growth and death
   04210 Apoptosis
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   04621 NOD-like receptor signaling pathway
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   04622 RIG-I-like receptor signaling pathway
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   04623 Cytosolic DNA-sensing pathway
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   04660 T cell receptor signaling pathway
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   04662 B cell receptor signaling pathway
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   04062 Chemokine signaling pathway
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
  Endocrine system
   04920 Adipocytokine signaling pathway
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
  Nervous system
   04722 Neurotrophin signaling pathway
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
  Development
   04380 Osteoclast differentiation
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   05203 Viral carcinogenesis
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   05220 Chronic myeloid leukemia
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   05215 Prostate cancer
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   05222 Small cell lung cancer
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
  Endocrine and metabolic diseases
   04931 Insulin resistance
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
  Infectious diseases
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   05131 Shigellosis
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   05134 Legionellosis
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   05166 HTLV-I infection
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   05162 Measles
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   05164 Influenza A
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   05161 Hepatitis B
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   05160 Hepatitis C
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   05168 Herpes simplex infection
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   05169 Epstein-Barr virus infection
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   05145 Toxoplasmosis
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   05140 Leishmaniasis
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   05142 Chagas disease (American trypanosomiasis)
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00686  Toll-like receptor signaling
     K04734  NFKBIA; NF-kappa-B inhibitor alpha
Transcription factors [BR:ko03000]
 Eukaryotic Type
  beta-Scaffold factors with minor groove contacts
   RHR (Rel homology region) Ankyrin only
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
4792(NFKBIA)
PTR: 
467426(NFKBIA)
PPS: 
100972867(NFKBIA)
GGO: 
101128204(NFKBIA)
PON: 
100459445(NFKBIA)
NLE: 
100599351(NFKBIA)
MCC: 
695335(NFKBIA)
MCF: 
RRO: 
104679802(NFKBIA)
CJC: 
100402266(NFKBIA)
MMU: 
18035(Nfkbia)
RNO: 
25493(Nfkbia)
CGE: 
100754153(Nfkbia)
NGI: 
103734016(Nfkbia)
HGL: 
101709256(Nfkbia)
OCU: 
100357341(NFKBIA)
TUP: 
102494635(NFKBIA)
CFA: 
480291(NFKBIA)
AML: 
100466997(NFKBIA)
UMR: 
103666055(NFKBIA)
FCA: 
101090622(NFKBIA)
PTG: 
102956127(NFKBIA)
BTA: 
282291(NFKBIA)
BOM: 
102275402(NFKBIA)
PHD: 
102316700(NFKBIA)
CHX: 
102169137(NFKBIA)
OAS: 
780520(NFKBIA)
SSC: 
406188(NFKBIA)
CFR: 
102519409(NFKBIA)
BACU: 
103002206(NFKBIA)
LVE: 
103069029(NFKBIA)
ECB: 
100058000(NFKBIA)
MYB: 
102256580(NFKBIA)
MYD: 
102763089(NFKBIA)
PALE: 
102891056(NFKBIA)
MDO: 
100011769(NFKBIA)
SHR: 
OAA: 
100090081(NFKBIA)
GGA: 
396093(NFKBIA)
MGP: 
100549878(NFKBIA)
APLA: 
101791396(NFKBIA)
TGU: 
100220015(NFKBIA)
GFR: 
102042109(NFKBIA)
FAB: 
101816754(NFKBIA)
PHI: 
102109715(NFKBIA)
CCW: 
104688451(NFKBIA)
FPG: 
101923842(NFKBIA)
FCH: 
102051665(NFKBIA)
CLV: 
102094222(NFKBIA)
ASN: 
102381268(NFKBIA)
AMJ: 
102559903(NFKBIA)
PSS: 
102460666(NFKBIA)
CMY: 
102937973(NFKBIA)
ACS: 
100554664(nfkbia)
PBI: 
103057929(NFKBIA)
XLA: 
446833(nfkbia) 734297
XTR: 
448138(nfkbia)
DRE: 
323099(nfkbiab) 406463(nfkbiaa)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102347685(NFKBIA)
CMK: 
103178533(nfkbia)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9990853
  Authors
Spencer E, Jiang J, Chen ZJ
  Title
Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCP.
  Journal
Genes Dev 13:284-94 (1999)

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