KEGG   ORTHOLOGY: K04734Help
Entry
K04734                      KO                                     

Name
NFKBIA
Definition
NF-kappa-B inhibitor alpha
Pathway
Chemokine signaling pathway
NF-kappa B signaling pathway
Apoptosis
Osteoclast differentiation
Toll-like receptor signaling pathway
NOD-like receptor signaling pathway
RIG-I-like receptor signaling pathway
Cytosolic DNA-sensing pathway
T cell receptor signaling pathway
B cell receptor signaling pathway
TNF signaling pathway
Neurotrophin signaling pathway
Adipocytokine signaling pathway
Epithelial cell signaling in Helicobacter pylori infection
Shigellosis
Legionellosis
Leishmaniasis
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Herpes simplex infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Prostate cancer
Chronic myeloid leukemia
Small cell lung cancer
Disease
H00007  
Hodgkin lymphoma
H00095  
Ectodermal dysplasia associated immunodeficiency (EDA-ID)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04064 NF-kappa B signaling pathway
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   04668 TNF signaling pathway
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
 Cellular Processes
  Cell growth and death
   04210 Apoptosis
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   04621 NOD-like receptor signaling pathway
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   04622 RIG-I-like receptor signaling pathway
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   04623 Cytosolic DNA-sensing pathway
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   04660 T cell receptor signaling pathway
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   04662 B cell receptor signaling pathway
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   04062 Chemokine signaling pathway
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
  Endocrine system
   04920 Adipocytokine signaling pathway
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
  Nervous system
   04722 Neurotrophin signaling pathway
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
  Development
   04380 Osteoclast differentiation
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   05203 Viral carcinogenesis
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   05220 Chronic myeloid leukemia
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   05215 Prostate cancer
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   05222 Small cell lung cancer
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
  Infectious diseases
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   05131 Shigellosis
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   05134 Legionellosis
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   05166 HTLV-I infection
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   05162 Measles
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   05164 Influenza A
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   05161 Hepatitis B
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   05160 Hepatitis C
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   05168 Herpes simplex infection
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   05169 Epstein-Barr virus infection
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   05145 Toxoplasmosis
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   05140 Leishmaniasis
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
   05142 Chagas disease (American trypanosomiasis)
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
Transcription factors [BR:ko03000]
 Eukaryotic Type
  beta-Scaffold factors with minor groove contacts
   RHR (Rel homology region) Ankyrin only
    K04734  NFKBIA; NF-kappa-B inhibitor alpha
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
4792(NFKBIA)
PTR: 
467426(NFKBIA)
PPS: 
100972867(NFKBIA)
GGO: 
101128204(NFKBIA)
PON: 
100459445(NFKBIA)
MCC: 
695335(NFKBIA)
MCF: 
MMU: 
18035(Nfkbia)
RNO: 
25493(Nfkbia)
CGE: 
HGL: 
101709256(Nfkbia)
TUP: 
102494635(NFKBIA)
CFA: 
480291(NFKBIA)
AML: 
FCA: 
101090622(NFKBIA)
PTG: 
102956127(NFKBIA)
BTA: 
282291(NFKBIA)
BOM: 
102275402(NFKBIA)
PHD: 
102316700(NFKBIA)
CHX: 
102169137(NFKBIA)
SSC: 
406188(NFKBIA)
CFR: 
102519409(NFKBIA)
ECB: 
100058000(NFKBIA)
MYB: 
102256580(NFKBIA)
MYD: 
102763089(NFKBIA)
PALE: 
102891056(NFKBIA)
MDO: 
100011769(NFKBIA)
SHR: 
OAA: 
100090081(NFKBIA)
GGA: 
396093(NFKBIA)
MGP: 
TGU: 
100220015(NFKBIA)
FAB: 
101816754(NFKBIA)
PHI: 
102109715(NFKBIA)
APLA: 
101791396(NFKBIA)
FPG: 
101923842(NFKBIA)
FCH: 
102051665(NFKBIA)
CLV: 
102094222(NFKBIA)
ASN: 
102381268(NFKBIA)
PSS: 
102460666(NFKBIA)
CMY: 
102937973(NFKBIA)
ACS: 
XLA: 
446833(nfkbia) 734297
XTR: 
448138(nfkbia)
DRE: 
323099(nfkbiab) 406463(nfkbiaa)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102347685(NFKBIA)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9990853
  Authors
Spencer E, Jiang J, Chen ZJ
  Title
Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCP.
  Journal
Genes Dev 13:284-94 (1999)

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