KEGG   ORTHOLOGY: K04809Help
Entry
K04809                      KO                                     

Name
CHRNA7
Definition
nicotinic acetylcholine receptor alpha-7
Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Cholinergic synapse
Nicotine addiction
Chemical carcinogenesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04020 Calcium signaling pathway
    K04809  CHRNA7; nicotinic acetylcholine receptor alpha-7
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04809  CHRNA7; nicotinic acetylcholine receptor alpha-7
 Organismal Systems
  Nervous system
   04725 Cholinergic synapse
    K04809  CHRNA7; nicotinic acetylcholine receptor alpha-7
 Human Diseases
  Cancers
   05204 Chemical carcinogenesis
    K04809  CHRNA7; nicotinic acetylcholine receptor alpha-7
  Substance dependence
   05033 Nicotine addiction
    K04809  CHRNA7; nicotinic acetylcholine receptor alpha-7
Ion channels [BR:ko04040]
 Cys-loop superfamily
  Acetylcholine (nicotinic)
   K04809  CHRNA7; nicotinic acetylcholine receptor alpha-7
BRITE hierarchy
Other DBs
GO: 
TC: 
Genes
HSA: 
1139(CHRNA7)
PTR: 
467639(CHRNA7)
PPS: 
GGO: 
PON: 
100456533(CHRNA7)
NLE: 
MCC: 
574230(CHRNA7)
MCF: 
102118754(CHRNA7)
CJC: 
MMU: 
11441(Chrna7)
RNO: 
25302(Chrna7)
CGE: 
NGI: 
HGL: 
101720562(Chrna7)
OCU: 
100342986(CHRNA7)
TUP: 
CFA: 
488696(CHRNA7)
AML: 
100469287(CHRNA7)
UMR: 
103659968(CHRFAM7A)
FCA: 
751113(CHRNA7)
PTG: 
102955772(CHRNA7)
BTA: 
282178(CHRNA7)
BOM: 
PHD: 
OAS: 
SSC: 
100415931(CHRNA7)
CFR: 
102524002(CHRNA7)
BACU: 
LVE: 
ECB: 
100060521(CHRNA7)
MYB: 
102246452(CHRNA7)
MYD: 
102764475(CHRNA7)
PALE: 
102889630(CHRNA7)
MDO: 
SHR: 
OAA: 
GGA: 
374001(CHRNA7) 396120
MGP: 
APLA: 
TGU: 
FAB: 
PHI: 
FPG: 
FCH: 
CLV: 
ASN: 
AMJ: 
PSS: 
CMY: 
ACS: 
PBI: 
XTR: 
DRE: 
394199(chrna7)
TRU: 
446017(a7a) 446018(a7b) 446024(Fr_a8a) 446089(a7c) 446091(Fr_a8b)
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
BFO: 
SPU: 
BMOR: 
100126173(nAChRb2)
LOA: 
HRO: 
LGI: 
HMG: 
EHX: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Buccafusco JJ
  Title
Neuronal nicotinic receptor subtypes: defining therapeutic targets.
  Journal
Mol Interv 4:285-95 (2004)
Reference
  Authors
Papke RL, Horenstein NA, Kulkarni AR, Stokes C, Corrie LW, Maeng CY, Thakur GA
  Title
The activity of GAT107, an allosteric activator and positive modulator of alpha7  nicotinic acetylcholine receptors (nAChR), is regulated by aromatic amino acids that span the subunit interface.
  Journal
J Biol Chem 289:4515-31 (2014)
  Sequence
[hsa:1139]

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