KEGG   ORTHOLOGY: K05062Help
Entry
K05062                      KO                                     

Name
LEPR, CD295
Definition
leptin receptor
Pathway
Cytokine-cytokine receptor interaction
Neuroactive ligand-receptor interaction
AMPK signaling pathway
Jak-STAT signaling pathway
Adipocytokine signaling pathway
Non-alcoholic fatty liver disease (NAFLD)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04630 Jak-STAT signaling pathway
    K05062  LEPR, CD295; leptin receptor
   04152 AMPK signaling pathway
    K05062  LEPR, CD295; leptin receptor
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05062  LEPR, CD295; leptin receptor
   04060 Cytokine-cytokine receptor interaction
    K05062  LEPR, CD295; leptin receptor
 Organismal Systems
  Endocrine system
   04920 Adipocytokine signaling pathway
    K05062  LEPR, CD295; leptin receptor
 Human Diseases
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K05062  LEPR, CD295; leptin receptor
Cytokine receptors [BR:ko04050]
 Class I cytokine receptor (hematopoietin family receptor)
  K05062  LEPR, CD295; leptin receptor
Cellular antigens [BR:ko04090]
 Proteins
  K05062  CD295, LEPR; leptin receptor
BRITE hierarchy
Genes
HSA: 
3953(LEPR)
PTR: 
456919(LEPR)
PPS: 
100975260(LEPR)
GGO: 
101141324(LEPR)
PON: 
100461924(LEPR)
NLE: 
100602850(LEPR)
MCC: 
574126(LEPR)
MCF: 
102115046(LEPR)
CSAB: 
103224669(LEPR)
RRO: 
104664347(LEPR)
CJC: 
100408177(LEPR)
SBQ: 
101027698(LEPR)
MMU: 
16847(Lepr)
RNO: 
24536(Lepr)
CGE: 
100756564(Lepr)
NGI: 
103732502(Lepr)
HGL: 
101705981(Lepr)
OCU: 
100351924(LEPR)
TUP: 
102474634(LEPR)
CFA: 
450207(LEPR)
AML: 
100470278(LEPR)
UMR: 
103663045(LEPR)
FCA: 
101085646(LEPR)
PTG: 
102958761(LEPR)
BTA: 
497205(LEPR)
BOM: 
102269476(LEPR)
PHD: 
CHX: 
102180987(LEPR)
OAS: 
443264(LEPR)
SSC: 
396836(LEPR)
CFR: 
BACU: 
103001028(LEPR)
LVE: 
103074895(LEPR)
ECB: 
100069504(LEPR)
MYB: 
102262387(LEPR)
MYD: 
102757565(LEPR)
PALE: 
102882664(LEPR)
LAV: 
100665796(LEPR)
MDO: 
100031062(LEPR)
SHR: 
100914129(LEPR)
OAA: 
100081526(LEPR)
GGA: 
374223(LEPR)
MGP: 
100125334(LEPR)
CJO: 
107317777(LEPR)
APLA: 
101790364(LEPR)
TGU: 
100229897(LEPR)
GFR: 
102041765(LEPR)
FAB: 
101806363(LEPR)
PHI: 
102100960(LEPR)
CCW: 
104695131(LEPR)
FPG: 
101921754(LEPR)
FCH: 
102049003(LEPR)
CLV: 
102083406(LEPR)
AAM: 
106487280(LEPR)
ASN: 
102381080(LEPR)
AMJ: 
102567366(LEPR)
PSS: 
102453831(LEPR)
CMY: 
102945650(LEPR)
ACS: 
100558934(lepr)
PBI: 
103065468(LEPR)
GJA: 
107114343(LEPR)
XTR: 
724071(lepr)
DRE: 
567241(lepr)
TRU: 
100174783(lepr)
TNG: 
MZE: 
101484846(lepr)
OLA: 
100301596(lepr)
XMA: 
102232722(lepr)
SASA: 
LCM: 
102364165(LEPR)
CMK: 
103189593(lepr)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8548812
  Authors
Tartaglia LA, Dembski M, Weng X, Deng N, Culpepper J, Devos R, Richards GJ, Campfield LA, Clark FT, Deeds J, Muir C, Sanker S, Moriarty A, Moore KJ, Smutko JS, Mays GG, Wool EA, Monroe CA, Tepper RI
  Title
Identification and expression cloning of a leptin receptor, OB-R.
  Journal
Cell 83:1263-71 (1995)
  Sequence
[hsa:3953]
Reference
  Authors
Villanueva EC, Myers MG Jr
  Title
Leptin receptor signaling and the regulation of mammalian physiology.
  Journal
Int J Obes (Lond) 32 Suppl 7:S8-12 (2008)

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