KEGG   ORTHOLOGY: K05068Help
Entry
K05068                      KO                                     

Name
IL2RA, CD25
Definition
interleukin 2 receptor alpha
Pathway
Cytokine-cytokine receptor interaction
Endocytosis
PI3K-Akt signaling pathway
Jak-STAT signaling pathway
Hematopoietic cell lineage
Measles
HTLV-I infection
Disease
H00091  
T-B+Severe combined immunodeficiencies (SCIDs)
H00408  
Type I diabetes mellitus
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04630 Jak-STAT signaling pathway
    K05068  IL2RA, CD25; interleukin 2 receptor alpha
   04151 PI3K-Akt signaling pathway
    K05068  IL2RA, CD25; interleukin 2 receptor alpha
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05068  IL2RA, CD25; interleukin 2 receptor alpha
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    K05068  IL2RA, CD25; interleukin 2 receptor alpha
 Organismal Systems
  Immune system
   04640 Hematopoietic cell lineage
    K05068  IL2RA, CD25; interleukin 2 receptor alpha
 Human Diseases
  Infectious diseases
   05166 HTLV-I infection
    K05068  IL2RA, CD25; interleukin 2 receptor alpha
   05162 Measles
    K05068  IL2RA, CD25; interleukin 2 receptor alpha
Cytokine receptors [BR:ko04050]
 Class I cytokine receptor (hematopoietin family receptor)
  K05068  IL2RA, CD25; interleukin 2 receptor alpha
Cellular antigens [BR:ko04090]
 Proteins
  K05068  CD25, IL2RA; interleukin 2 receptor, alpha
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
3559(IL2RA)
PTR: 
450884(IL2RA)
PPS: 
100974407(IL2RA)
GGO: 
101126210(IL2RA)
PON: 
100440118(IL2RA)
MCC: 
574300(IL2RA)
MCF: 
102123605(IL2RA)
MMU: 
16184(Il2ra)
RNO: 
25704(Il2ra)
CGE: 
100764797(Il2ra)
HGL: 
101696651(Il2ra)
TUP: 
102503225(IL2RA)
CFA: 
403870(IL2RA)
AML: 
FCA: 
493953(IL2RA)
PTG: 
BTA: 
281861(IL2RA)
BOM: 
102274858(IL2RA)
PHD: 
102323894(IL2RA)
CHX: 
102170059(IL2RA)
SSC: 
396814(IL2RA)
CFR: 
102520401(IL2RA)
BACU: 
102999308(IL2RA)
LVE: 
103090256(IL2RA)
ECB: 
100070292(IL2RA)
MYB: 
102249529(IL2RA)
MYD: 
102769642(IL2RA)
PALE: 
102891511(IL2RA)
GGA: 
395294(IL2RA)
MGP: 
TGU: 
FAB: 
PHI: 
APLA: 
FPG: 
FCH: 
CLV: 
102090507(IL2RA)
ASN: 
CMY: 
102937403(IL2RA)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8476561
  Authors
Minami Y, Kono T, Miyazaki T, Taniguchi T
  Title
The IL-2 receptor complex: its structure, function, and target genes.
  Journal
Annu Rev Immunol 11:245-68 (1993)
Reference
  Authors
Knevel R, de Rooy DP, Zhernakova A, Grondal G, Krabben A, Steinsson K, Wijmenga C, Cavet G, Toes RE, Huizinga TW, Gregersen PK, van der Helm-van Mil AH
  Title
Association of variants in IL2RA with progression of joint destruction in rheumatoid arthritis.
  Journal
Arthritis Rheum 65:1684-93 (2013)

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