KEGG   ORTHOLOGY: K05069Help
Entry
K05069                      KO                                     

Name
IL2RB, CD122
Definition
interleukin 2 receptor beta
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04144  Endocytosis
ko04151  PI3K-Akt signaling pathway
ko04630  Jak-STAT signaling pathway
ko04658  Th1 and Th2 cell differentiation
ko04659  Th17 cell differentiation
ko05162  Measles
ko05166  HTLV-I infection
ko05200  Pathways in cancer
ko05202  Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04630 Jak-STAT signaling pathway
    K05069  IL2RB, CD122; interleukin 2 receptor beta
   04151 PI3K-Akt signaling pathway
    K05069  IL2RB, CD122; interleukin 2 receptor beta
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05069  IL2RB, CD122; interleukin 2 receptor beta
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    K05069  IL2RB, CD122; interleukin 2 receptor beta
 Organismal Systems
  Immune system
   04658 Th1 and Th2 cell differentiation
    K05069  IL2RB, CD122; interleukin 2 receptor beta
   04659 Th17 cell differentiation
    K05069  IL2RB, CD122; interleukin 2 receptor beta
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K05069  IL2RB, CD122; interleukin 2 receptor beta
   05202 Transcriptional misregulation in cancers
    K05069  IL2RB, CD122; interleukin 2 receptor beta
  Infectious diseases
   05166 HTLV-I infection
    K05069  IL2RB, CD122; interleukin 2 receptor beta
   05162 Measles
    K05069  IL2RB, CD122; interleukin 2 receptor beta
Cytokine receptors [BR:ko04050]
 Class I cytokine receptor (hematopoietin family receptor)
  K05069  IL2RB, CD122; interleukin 2 receptor beta
CD molecules [BR:ko04090]
 Proteins
  K05069  CD122, IL2RB; interleukin 2 receptor, beta
BRITE hierarchy
Other DBs
GO: 0004911
Genes
HSA: 3560(IL2RB)
PTR: 470203(IL2RB)
PPS: 100992438(IL2RB)
GGO: 101139583(IL2RB)
PON: 100460977(IL2RB)
NLE: 100581366(IL2RB)
MCC: 696331(IL2RB)
MCF: 102138714(IL2RB)
CSAB: 103223268(IL2RB)
RRO: 104682498(IL2RB)
RBB: 108512733(IL2RB)
CJC: 100394910(IL2RB)
SBQ: 101030332(IL2RB)
MMU: 16185(Il2rb)
RNO: 25746(Il2rb)
CGE: 100769948(Il2rb)
NGI: 103748643(Il2rb)
HGL: 101726369(Il2rb)
CCAN: 109698250(Il2rb)
OCU: 103346218(IL2RB)
TUP: 102467660(IL2RB)
CFA: 403439(IL2RB)
AML: 100478292(IL2RB)
UMR: 103676409(IL2RB)
ORO: 101366322(IL2RB)
FCA: 101092622(IL2RB)
PTG: 102965369(IL2RB)
AJU: 106981084(IL2RB)
BTA: 104968644(IL2RB) 510185
BOM: 102284639(IL2RB) 106700824
BIU: 109559534(IL2RB)
OAS: 101107088(IL2RB) 105614809
SSC: 100621776(IL2RB)
CFR: 102524470(IL2RB)
CDK: 105101578(IL2RB)
BACU: 103006990(IL2RB)
LVE: 103071005(IL2RB)
OOR: 101271954(IL2RB)
ECB: 100069676(IL2RB)
EPZ: 103564462(IL2RB)
EAI: 106837581(IL2RB)
MYB: 102241115(IL2RB)
MYD: 102768408(IL2RB)
HAI: 109394467(IL2RB)
RSS: 109439339
PALE: 102883396(IL2RB)
LAV: 100669139(IL2RB)
TMU: 101344371
MDO: 100025393(IL2RB)
SHR: 100913275(IL2RB)
OAA: 100092851(IL2RB)
GGA: 100859707(IL2RB)
MGP: 104911125(IL2RB)
CJO: 107313789(IL2RB)
APLA: 101791719(IL2RB)
ACYG: 106035899(IL2RB)
TGU: 101232975(IL2RB)
GFR: 102031500(IL2RB)
FAB: 101809303(IL2RB)
PHI: 102106386(IL2RB)
PMAJ: 107204849(IL2RB)
CCW: 104696293(IL2RB)
FPG: 101915263(IL2RB)
FCH: 102058748(IL2RB)
CLV: 102091469(IL2RB)
EGZ: 104134213(IL2RB)
AAM: 106488409(IL2RB) 106490665
ASN: 102376875(IL2RB)
AMJ: 102571730(IL2RB)
PSS: 102449512(IL2RB)
CMY: 102936500(IL2RB)
CPIC: 101932173(IL2RB)
ACS: 103278848(il2rb)
PVT: 110075925(IL2RB)
GJA: 107120056(IL2RB)
XTR: 101731938(il2rb)
DRE: 793920(il2rb)
IPU: 108272990 108273212(il2rb)
TRU: 101076872(il2rb)
NCC: 104964346
OLA: 101165891 105354598(csf2rb)
PRET: 103468486
LCF: 108877635(il2rb) 108889056
HCQ: 109520288
LCM: 102367350
CMK: 103189779(il2rb)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2785715
  Authors
Hatakeyama M, Tsudo M, Minamoto S, Kono T, Doi T, Miyata T, Miyasaka M, Taniguchi T
  Title
Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's.
  Journal
Science 244:551-6 (1989)
DOI:10.1126/science.2785715
  Sequence
[hsa:3560]
Reference
PMID:8476561
  Authors
Minami Y, Kono T, Miyazaki T, Taniguchi T
  Title
The IL-2 receptor complex: its structure, function, and target genes.
  Journal
Annu Rev Immunol 11:245-68 (1993)
DOI:10.1146/annurev.iy.11.040193.001333
Reference
  Authors
Bucheton B, Argiro L, Chevillard C, Marquet S, Kheir MM, Mergani A, El-Safi SH, Dessein AJ
  Title
Identification of a novel G245R polymorphism in the IL-2 receptor beta membrane proximal domain associated with human visceral leishmaniasis.
  Journal
Genes Immun 8:79-83 (2007)
DOI:10.1038/sj.gene.6364355
  Sequence
[hsa:3560]

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