KEGG   ORTHOLOGY: K05070Help
Entry
K05070                      KO                                     

Name
IL2RG
Definition
interleukin 2 receptor gamma
Pathway
Cytokine-cytokine receptor interaction
Endocytosis
PI3K-Akt signaling pathway
Jak-STAT signaling pathway
Measles
HTLV-I infection
Inflammatory bowel disease (IBD)
Primary immunodeficiency
Disease
H00091  
T-B+Severe combined immunodeficiencies (SCIDs)
H00093  
Combined immunodeficiencies (CIDs)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04630 Jak-STAT signaling pathway
    K05070  IL2RG; interleukin 2 receptor gamma
   04151 PI3K-Akt signaling pathway
    K05070  IL2RG; interleukin 2 receptor gamma
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05070  IL2RG; interleukin 2 receptor gamma
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    K05070  IL2RG; interleukin 2 receptor gamma
 Human Diseases
  Immune diseases
   05321 Inflammatiory bowel disease (IBD)
    K05070  IL2RG; interleukin 2 receptor gamma
   05340 Primary immunodeficiency
    K05070  IL2RG; interleukin 2 receptor gamma
  Infectious diseases
   05166 HTLV-I infection
    K05070  IL2RG; interleukin 2 receptor gamma
   05162 Measles
    K05070  IL2RG; interleukin 2 receptor gamma
Cytokine receptors [BR:ko04050]
 Class I cytokine receptor (hematopoietin family receptor)
  K05070  IL2RG; interleukin 2 receptor gamma
Cellular antigens [BR:ko04090]
 Proteins
  K05070  CD132, IL2RG; interleukin 2 receptor, gamma (severe combined immunodeficiency)
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
3561(IL2RG)
PTR: 
101059843 465692(CXHXorf65)
PPS: 
100986679(IL2RG)
GGO: 
101134845(IL2RG)
PON: 
100454903(IL2RG)
MCC: 
641338(IL2RG)
MCF: 
102144912(IL2RG)
MMU: 
16186(Il2rg)
RNO: 
140924(Il2rg)
HGL: 
101715243(Il2rg)
TUP: 
102476004(IL2RG)
CFA: 
403851(IL2RG)
AML: 
FCA: 
101090239(IL2RG)
PTG: 
102966580(IL2RG)
BTA: 
281862(IL2RG)
BOM: 
102266681(IL2RG)
PHD: 
102319279(IL2RG)
CHX: 
102169656(IL2RG)
SSC: 
397156(IL2RG)
CFR: 
102518550(IL2RG)
BACU: 
103016442(IL2RG)
LVE: 
103087530(IL2RG)
ECB: 
100055911(IL2RG)
MYB: 
102241164(IL2RG)
MYD: 
102757155(IL2RG)
PALE: 
102888070(IL2RG)
MDO: 
100619507(IL2RG)
SHR: 
100929781(IL2RG)
GGA: 
395199(IL2RG)
TGU: 
100226174(IL2RG)
PHI: 
102112500(IL2RG)
APLA: 
101794194(IL2RG)
FPG: 
101923008(IL2RG)
FCH: 
102052025(IL2RG)
CLV: 
102094834(IL2RG)
ASN: 
102379602(IL2RG)
AMJ: 
102575498(IL2RG)
PSS: 
CMY: 
102933244(IL2RG)
PBI: 
103061889(IL2RG)
XTR: 
DRE: 
100144554(il2rgb) 796604(il2rga)
TRU: 
100190946(il2rga)
MZE: 
OLA: 
XMA: 
LCM: 
102356230(IL2RG)
CMK: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8476561
  Authors
Minami Y, Kono T, Miyazaki T, Taniguchi T
  Title
The IL-2 receptor complex: its structure, function, and target genes.
  Journal
Annu Rev Immunol 11:245-68 (1993)
Reference
  Authors
Zhang Q, Wang HY, Liu X, Bhutani G, Kantekure K, Wasik M
  Title
IL-2R common gamma-chain is epigenetically silenced by nucleophosphin-anaplastic  lymphoma kinase (NPM-ALK) and acts as a tumor suppressor by targeting NPM-ALK.
  Journal
Proc Natl Acad Sci U S A 108:11977-82 (2011)

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