KEGG   ORTHOLOGY: K05072Help
Entry
K05072                      KO                                     

Name
IL7R, CD127
Definition
interleukin 7 receptor
Pathway
Cytokine-cytokine receptor interaction
FoxO signaling pathway
PI3K-Akt signaling pathway
Jak-STAT signaling pathway
Hematopoietic cell lineage
Primary immunodeficiency
Disease
H00091  
T-B+Severe combined immunodeficiencies (SCIDs)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04630 Jak-STAT signaling pathway
    K05072  IL7R, CD127; interleukin 7 receptor
   04068 FoxO signaling pathway
    K05072  IL7R, CD127; interleukin 7 receptor
   04151 PI3K-Akt signaling pathway
    K05072  IL7R, CD127; interleukin 7 receptor
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05072  IL7R, CD127; interleukin 7 receptor
 Organismal Systems
  Immune system
   04640 Hematopoietic cell lineage
    K05072  IL7R, CD127; interleukin 7 receptor
 Human Diseases
  Immune diseases
   05340 Primary immunodeficiency
    K05072  IL7R, CD127; interleukin 7 receptor
Cytokine receptors [BR:ko04050]
 Class I cytokine receptor (hematopoietin family receptor)
  K05072  IL7R, CD127; interleukin 7 receptor
Cellular antigens [BR:ko04090]
 Proteins
  K05072  CD127, IL7R; interleukin 7 receptor
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
3575(IL7R)
PTR: 
461922(IL7R)
PPS: 
100981232(IL7R)
GGO: 
101140372(IL7R)
PON: 
100461835(IL7R)
NLE: 
100583768(IL7R)
MCC: 
699869(IL7R)
MCF: 
102143679(IL7R)
CSAB: 
103215123(IL7R)
RRO: 
104662030(IL7R)
CJC: 
100397720(IL7R)
SBQ: 
101044161(IL7R)
MMU: 
16197(Il7r)
RNO: 
294797(Il7r)
CGE: 
100757700(Il7r)
NGI: 
103741311(Il7r)
HGL: 
101710077(Il7r)
OCU: 
100343726(IL7R)
TUP: 
102499643(IL7R)
CFA: 
612582(IL7R)
AML: 
100477617(IL7R)
UMR: 
103664716(IL7R)
FCA: 
101100697(IL7R)
PTG: 
102953956(IL7R)
BTA: 
521554(IL7R)
BOM: 
102284629(IL7R)
PHD: 
102341432(IL7R)
CHX: 
102175248(IL7R)
OAS: 
101111126(IL7R)
SSC: 
100271930(IL7R)
CFR: 
102515501(IL7R)
BACU: 
103010049(IL7R)
LVE: 
103089375(IL7R)
ECB: 
100034169(IL7R)
MYB: 
102264253(IL7R)
MYD: 
102772772(IL7R)
PALE: 
102889092(IL7R)
LAV: 
100671266(IL7R)
MDO: 
100020565(IL7R)
SHR: 
100915478(IL7R)
OAA: 
100078445(IL7R)
GGA: 
426054(IL7R)
MGP: 
100542453(IL7R)
CJO: 
107305872(IL7R)
APLA: 
101800042(IL7R)
TGU: 
100226205(IL7R)
GFR: 
102033898(IL7R)
FAB: 
101816330(IL7R)
PHI: 
102109259(IL7R)
CCW: 
104686602(IL7R)
FPG: 
101911430(IL7R)
FCH: 
102052979(IL7R)
CLV: 
102085807(IL7R)
AAM: 
106499523(IL7R)
ASN: 
102368640(IL7R)
AMJ: 
102558184(IL7R)
PSS: 
102449770(IL7R)
CMY: 
102932302(IL7R)
ACS: 
103279695(il7r)
PBI: 
103058565(IL7R)
GJA: 
107108287(IL7R)
XTR: 
105947992(il7r)
DRE: 
100134973(il7r)
TRU: 
101078727(il7r)
MZE: 
101477974(il7r)
XMA: 
102218066(il7r)
SASA: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2317865
  Authors
Goodwin RG, Friend D, Ziegler SF, Jerzy R, Falk BA, Gimpel S, Cosman D, Dower SK, March CJ, Namen AE, et al.
  Title
Cloning of the human and murine interleukin-7 receptors: demonstration of a soluble form and homology to a new receptor superfamily.
  Journal
Cell 60:941-51 (1990)
  Sequence
[hsa:3575]
Reference
PMID:8266077
  Authors
Noguchi M, Nakamura Y, Russell SM, Ziegler SF, Tsang M, Cao X, Leonard WJ
  Title
Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor.
  Journal
Science 262:1877-80 (1993)

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