KEGG   ORTHOLOGY: K05075Help
Entry
K05075                      KO                                     

Name
IL21R, CD360
Definition
interleukin 21 receptor
Pathway
Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway
Th17 cell differentiation
Inflammatory bowel disease (IBD)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04630 Jak-STAT signaling pathway
    K05075  IL21R, CD360; interleukin 21 receptor
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05075  IL21R, CD360; interleukin 21 receptor
 Organismal Systems
  Immune system
   04659 Th17 cell differentiation
    K05075  IL21R, CD360; interleukin 21 receptor
 Human Diseases
  Immune diseases
   05321 Inflammatiory bowel disease (IBD)
    K05075  IL21R, CD360; interleukin 21 receptor
Cytokine receptors [BR:ko04050]
 Class I cytokine receptor (hematopoietin family receptor)
  K05075  IL21R, CD360; interleukin 21 receptor
CD molecules [BR:ko04090]
 Proteins
  K05075  CD360, IL21R; interleukin 21 receptor
BRITE hierarchy
Genes
HSA: 
50615(IL21R)
PTR: 
454006(IL21R)
PPS: 
100970355(IL21R)
GGO: 
101129403(IL21R)
PON: 
100450175(IL21R)
NLE: 
100601027(IL21R)
MCC: 
705759(IL21R)
MCF: 
102135042(IL21R)
CSAB: 
103230109(IL21R)
RRO: 
RBB: 
108518245(IL21R)
CJC: 
SBQ: 
101045058(IL21R)
MMU: 
60504(Il21r)
RNO: 
308977(Il21r)
CGE: 
100763133(Il21r)
NGI: 
103741072(Il21r)
HGL: 
101701307(Il21r)
CCAN: 
109698035(Il21r)
OCU: 
103348594(IL21R)
TUP: 
102469112(IL21R)
CFA: 
608011(IL21R)
AML: 
100467688(IL21R)
UMR: 
103657903(IL21R)
FCA: 
101096026(IL21R)
PTG: 
102949594(IL21R)
AJU: 
106966181(IL21R)
BTA: 
617967(IL21R)
BOM: 
102274052(IL21R)
BIU: 
109578841(IL21R)
PHD: 
102337002(IL21R)
CHX: 
102176844(IL21R)
OAS: 
100820753(IL21R)
SSC: 
100518723(IL21R)
CFR: 
102505205(IL21R)
CDK: 
105098255(IL21R)
BACU: 
103018703(IL21R)
LVE: 
103085231(IL21R)
ECB: 
100066814(IL21R)
EPZ: 
103556346(IL21R)
EAI: 
106829084(IL21R)
MYB: 
102263626(IL21R)
MYD: 
102762032(IL21R)
HAI: 
109385808(IL21R)
RSS: 
109438296(IL21R)
PALE: 
102883062(IL21R)
LAV: 
100655109(IL21R)
MDO: 
100016040(IL21R)
SHR: 
100920794(IL21R)
OAA: 
100079376(IL21R)
GGA: 
416586(IL21R)
MGP: 
100547386(IL21R)
CJO: 
107320804(IL21R)
APLA: 
101796991(IL21R)
ACYG: 
106046044(IL21R)
TGU: 
100230851(IL21R)
GFR: 
102032622(IL21R)
FAB: 
101812777(IL21R)
PHI: 
102107481(IL21R)
PMAJ: 
107211180(IL21R)
CCW: 
104684905(IL21R)
FPG: 
101913915(IL21R)
FCH: 
102059759(IL21R)
CLV: 
102087878(IL21R)
AAM: 
106486130(IL21R)
ASN: 
102385153(IL21R)
AMJ: 
102563981(IL21R)
PSS: 
102460432(IL21R)
CMY: 
102946561(IL21R)
CPIC: 
101943915(IL21R)
ACS: 
103281084(il21r)
PBI: 
103064799(IL21R)
GJA: 
107106230(IL21R)
XLA: 
108701892(il21r.L) 108702308(il21r.S)
XTR: 
100492452(il21r)
NPR: 
108794714(IL21R)
DRE: 
100134976(il21r.1)
SRX: 
SANH: 
SGH: 
IPU: 
108257366(il21r)
AMEX: 
103026064(il21r)
TRU: 
LCO: 
104934035(il21r)
NCC: 
MZE: 
OLA: 
XMA: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
105013397(il21r)
SFM: 
LCM: 
CMK: 
103186639(il21r)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Parrish-Novak J, Dillon SR, Nelson A, Hammond A, Sprecher C, Gross JA, Johnston J, Madden K, Xu W, West J, Schrader S, Burkhead S, Heipel M, Brandt C, Kuijper JL, Kramer J, Conklin D, Presnell SR, Berry J, Shiota F, Bort S, Hambly K, Mudri S, Clegg C, Moore M, Grant FJ, Lofton-Day C, Gilbert T, Rayond F, Ching A, Yao L, Smith D, Webster P, Whitmore T, Maurer M, Kaushansky K, Holly RD, Foster D
  Title
Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function.
  Journal
Nature 408:57-63 (2000)
DOI:10.1038/35040504
  Sequence
[hsa:50615]
Reference
  Authors
Leonard WJ, Zeng R, Spolski R
  Title
Interleukin 21: a cytokine/cytokine receptor system that has come of age.
  Journal
J Leukoc Biol 84:348-56 (2008)
DOI:10.1189/jlb.0308149

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