KEGG   ORTHOLOGY: K05084Help
Entry
K05084                      KO                                     
Name
ERBB3, HER3
Definition
receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
Pathway
ErbB signaling pathway
Calcium signaling pathway
Endocytosis
Proteoglycans in cancer
Disease
H00408  
Type I diabetes mellitus
H00865  
Lethal congenital contractural syndrome (LCCS)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04012 ErbB signaling pathway
    K05084  ERBB3, HER3; receptor tyrosine-protein kinase erbB-3
   04020 Calcium signaling pathway
    K05084  ERBB3, HER3; receptor tyrosine-protein kinase erbB-3
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    K05084  ERBB3, HER3; receptor tyrosine-protein kinase erbB-3
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    K05084  ERBB3, HER3; receptor tyrosine-protein kinase erbB-3
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     K05084  ERBB3, HER3; receptor tyrosine-protein kinase erbB-3
Protein kinases [BR:ko01001]
 Tyrosine protein kinases
  EGFR family
   K05084  ERBB3, HER3; receptor tyrosine-protein kinase erbB-3
Enzyme-linked receptors [BR:ko01020]
 Receptor tyrosine kinases
  RTK class I (EGF receptor family)
   K05084  ERBB3, HER3; receptor tyrosine-protein kinase erbB-3
Cytokine receptors [BR:ko04050]
 Receptor tyrosine kinase
  RTK class I (EGF receptor family)
   K05084  ERBB3, HER3; receptor tyrosine-protein kinase erbB-3
BRITE hierarchy
Genes
HSA: 
2065(ERBB3)
PTR: 
451980(ERBB3)
PPS: 
100974494(ERBB3)
GGO: 
PON: 
100174431(ERBB3)
MCC: 
711407(ERBB3)
MMU: 
13867(Erbb3)
RNO: 
29496(Erbb3)
CFA: 
481105(ERBB3)
AML: 
100468735(ERBB3)
FCA: 
101085388(ERBB3)
BTA: 
785655(ERBB3)
SSC: 
100157538
ECB: 
100059216(ERBB3)
MDO: 
100028072 100028103(ERBB3)
SHR: 
100924586(ERBB3)
OAA: 
100092326
GGA: 
693245(ERBB3)
ACS: 
100556326
XTR: 
100493384(erbb3)
DRE: 
100149258 386635(erbb3a) 544664(erbb3b)
TRU: 
101061551 101069394
OLA: 
101172402 101172978
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Holbro T, Hynes NE.
  Title
ErbB receptors: directing key signaling networks throughout life.
  Journal
Annu Rev Pharmacol Toxicol 44:195-217 (2004)
Reference
  Authors
Citri A, Yarden Y.
  Title
EGF-ERBB signalling: towards the systems level.
  Journal
Nat Rev Mol Cell Biol 7:505-16 (2006)
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