KEGG   ORTHOLOGY: K05085Help
Entry
K05085                      KO                                     

Name
ERBB4, HER4
Definition
receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
Pathway
ko04010  MAPK signaling pathway
ko04012  ErbB signaling pathway
ko04020  Calcium signaling pathway
ko04151  PI3K-Akt signaling pathway
ko05205  Proteoglycans in cancer
Disease
H00058  Amyotrophic lateral sclerosis (ALS)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K05085  ERBB4, HER4; receptor tyrosine-protein kinase erbB-4
   04012 ErbB signaling pathway
    K05085  ERBB4, HER4; receptor tyrosine-protein kinase erbB-4
   04020 Calcium signaling pathway
    K05085  ERBB4, HER4; receptor tyrosine-protein kinase erbB-4
   04151 PI3K-Akt signaling pathway
    K05085  ERBB4, HER4; receptor tyrosine-protein kinase erbB-4
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    K05085  ERBB4, HER4; receptor tyrosine-protein kinase erbB-4
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     K05085  ERBB4, HER4; receptor tyrosine-protein kinase erbB-4
Protein kinases [BR:ko01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   K05085  ERBB4, HER4; receptor tyrosine-protein kinase erbB-4
BRITE hierarchy
Genes
HSA: 2066(ERBB4)
PTR: 459919(ERBB4)
PPS: 100996186(ERBB4)
GGO: 101131773(ERBB4)
PON: 100938677(ERBB4)
NLE: 100598496(ERBB4)
MCC: 693341(ERBB4)
MCF: 102141308(ERBB4)
CSAB: 103217777(ERBB4)
RRO: 104658903(ERBB4)
RBB: 108517585(ERBB4)
CJC: 100402965(ERBB4)
SBQ: 101049355(ERBB4)
MMU: 13869(Erbb4)
RNO: 59323(Erbb4)
CGE: 100760475
NGI: 103744489(Erbb4)
HGL: 101725806(Erbb4)
OCU: 100009328(ERBB4)
TUP: 102482008(ERBB4)
CFA: 488508(ERBB4)
AML: 100470612(ERBB4)
UMR: 103659965(ERBB4)
FCA: 101100073(ERBB4)
PTG: 102950188(ERBB4)
AJU: 106974147(ERBB4)
BTA: 522419(ERBB4)
BOM: 102265783(ERBB4)
PHD: 102341244(ERBB4)
CHX: 102180167(ERBB4)
OAS: 101103044(ERBB4)
SSC: 100525789(ERBB4)
CFR: 102522654(ERBB4)
CDK: 105099620(ERBB4)
BACU: 103004826(ERBB4)
LVE: 103078350(ERBB4)
OOR: 101278439(ERBB4)
ECB: 100050182(ERBB4)
EAI: 106837675(ERBB4)
MYB: 102241613(ERBB4)
MYD: 102765674(ERBB4)
HAI: 109390432(ERBB4)
RSS: 109445056(ERBB4)
PALE: 102895574(ERBB4)
LAV: 100656755(ERBB4) 111748890
MDO: 100014865(ERBB4)
SHR: 100931663(ERBB4)
OAA: 100077353(ERBB4)
GGA: 395671(ERBB4)
MGP: 100539508(ERBB4)
CJO: 107316482(ERBB4)
APLA: 101801144(ERBB4)
ACYG: 106034472(ERBB4)
TGU: 100231016(ERBB4)
GFR: 102045033(ERBB4)
FAB: 101808540(ERBB4)
PHI: 102113512(ERBB4)
PMAJ: 107207560(ERBB4)
CCW: 104694541(ERBB4)
FPG: 101910610(ERBB4)
FCH: 102046664(ERBB4)
CLV: 102091363(ERBB4)
EGZ: 104124291(ERBB4)
AAM: 106492330(ERBB4)
ASN: 102387680(ERBB4)
AMJ: 102559834(ERBB4)
CMY: 102939092(ERBB4)
CPIC: 101941047(ERBB4)
ACS: 100558986(erbb4)
PVT: 110072384(ERBB4)
PBI: 103055996(ERBB4)
GJA: 107120657(ERBB4)
XLA: 108703039 724070(erbb4.L)
XTR: 100493234(erbb4)
NPR: 108792763(ERBB4) 108797054
DRE: 100007677(erbb4a) 101885162(si:ch73-383l1.1) 569836(erbb4b)
IPU: 108258402 108258873(ErbB4a) 108266386(erbb4)
AMEX: 103033543(erbb4) 103038099
TRU: 101074687(erbb4) 101079286
LCO: 104928902 104929362(erbb4)
MZE: 101467929(erbb4) 101478875
OLA: 101165111(erbb4) 101165379
XMA: 102230380(erbb4) 102231767
PRET: 103461563 103476823(erbb4)
CSEM: 103389576(erbb4) 103392212
LCF: 108873032(erbb4) 108880453
BPEC: 110156208 110170911(erbb4)
SFM: 108922269 108928922(erbb4)
LCM: 102360220(ERBB4)
CMK: 103182941(erbb4) 103190236(erbb3)
SKO: 100313534
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Holbro T, Hynes NE.
  Title
ErbB receptors: directing key signaling networks throughout life.
  Journal
Annu Rev Pharmacol Toxicol 44:195-217 (2004)
DOI:10.1146/annurev.pharmtox.44.101802.121440
Reference
  Authors
Citri A, Yarden Y.
  Title
EGF-ERBB signalling: towards the systems level.
  Journal
Nat Rev Mol Cell Biol 7:505-16 (2006)
DOI:10.1038/nrm1962

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