KEGG ORTHOLOGY: K05089

ORTHOLOGY: K05089

Entry

K05089 KO

Name

PDGFRB

Definition

platelet-derived growth factor receptor beta [EC:2.7.10.1]

Pathway

ko04010	MAPK signaling pathway
ko04020	Calcium signaling pathway
ko04060	Cytokine-cytokine receptor interaction
ko04151	PI3K-Akt signaling pathway
ko04510	Focal adhesion
ko04540	Gap junction
ko04810	Regulation of actin cytoskeleton
ko05166	HTLV-I infection
ko05200	Pathways in cancer
ko05214	Glioma
ko05215	Prostate cancer
ko05218	Melanoma

Disease

H00042

Glioma

Brite

KEGG Orthology (KO) [BR:ko00001]
Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K05089  PDGFRB; platelet-derived growth factor receptor beta
   04020 Calcium signaling pathway
    K05089  PDGFRB; platelet-derived growth factor receptor beta
   04151 PI3K-Akt signaling pathway
    K05089  PDGFRB; platelet-derived growth factor receptor beta
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05089  PDGFRB; platelet-derived growth factor receptor beta
Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    K05089  PDGFRB; platelet-derived growth factor receptor beta
  Cell communication
   04510 Focal adhesion
    K05089  PDGFRB; platelet-derived growth factor receptor beta
   04540 Gap junction
    K05089  PDGFRB; platelet-derived growth factor receptor beta
Human Diseases
  Cancers
   05200 Pathways in cancer
    K05089  PDGFRB; platelet-derived growth factor receptor beta
   05214 Glioma
    K05089  PDGFRB; platelet-derived growth factor receptor beta
   05218 Melanoma
    K05089  PDGFRB; platelet-derived growth factor receptor beta
   05215 Prostate cancer
    K05089  PDGFRB; platelet-derived growth factor receptor beta
  Infectious diseases
   05166 HTLV-I infection
    K05089  PDGFRB; platelet-derived growth factor receptor beta
Enzymes [BR:ko01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     K05089  PDGFRB; platelet-derived growth factor receptor beta
Protein kinases [BR:ko01001]
Tyrosine protein kinases
  PDGFR family
   K05089  PDGFRB; platelet-derived growth factor receptor beta
Enzyme-linked receptors [BR:ko01020]
Receptor tyrosine kinases
  RTK class III (PDGF receptor family)
   K05089  PDGFRB; platelet-derived growth factor receptor beta
Cytokine receptors [BR:ko04050]
Receptor tyrosine kinase
  RTK class III (PDGF receptor family)
   K05089  PDGFRB; platelet-derived growth factor receptor beta
Cellular antigens [BR:ko04090]
Proteins
  K05089  CD140b, PDGFRB; platelet-derived growth factor receptor, beta polypeptide

Other DBs

GO:

0004992

Genes

HSA:	5159(PDGFRB)
PTR:	462188(PDGFRB)
PPS:	100975853(PDGFRB)
GGO:	101150577(PDGFRB)
PON:	100460001(PDGFRB)
MCC:	711353(PDGFRB)
MMU:	18596(Pdgfrb)
RNO:	24629(Pdgfrb)
CFA:	442985(PDGFRB)
AML:	100472005
FCA:	101084600(PDGFRB)
BTA:	527165(PDGFRB)
SSC:	100126842(PDGFRB)
ECB:	100071665
MDO:	100028943
SHR:	100917212(PDGFRB)
OAA:	100079459(PDGFRB)
GGA:	770488(PDGFRB)
MGP:	100550611
TGU:	100223375(PDGFRB)
ACS:	100555784
XTR:	100487523
DRE:	559529(pdgfrb)
TRU:	101074724
OLA:	101155039
AQU:	100631815

» show all

Reference

PMID:15583853

Authors

Jones AV, Cross NC

Title

Oncogenic derivatives of platelet-derived growth factor receptors.

Journal

Cell Mol Life Sci 61:2912-23 (2004)

All links

Ontology (14)   
   KEGG BRITE (13)   
   GO (1)   
Pathway (24)   
   KEGG PATHWAY (24)   
Disease (1)   
   KEGG DISEASE (1)   
Drug (32)   
   KEGG DRUG (32)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (41)   
   KEGG GENES (26)   
   KEGG DGENES (2)   
   KEGG EGENES (10)   
   KEGG MGENES (3)   
Protein sequence (10)   
   UniProt (10)   
Literature (1)   
   PubMed (1)   
All databases (124)   

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