KEGG   ORTHOLOGY: K05089Help
Entry
K05089                      KO                                     

Name
PDGFRB
Definition
platelet-derived growth factor receptor beta [EC:2.7.10.1]
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Calcium signaling pathway
Cytokine-cytokine receptor interaction
PI3K-Akt signaling pathway
Focal adhesion
Gap junction
Regulation of actin cytoskeleton
HTLV-I infection
Pathways in cancer
MicroRNAs in cancer
Glioma
Prostate cancer
Melanoma
Central carbon metabolism in cancer
Choline metabolism in cancer
Disease
H00042  
Glioma
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K05089  PDGFRB; platelet-derived growth factor receptor beta
   04015 Rap1 signaling pathway
    K05089  PDGFRB; platelet-derived growth factor receptor beta
   04010 MAPK signaling pathway
    K05089  PDGFRB; platelet-derived growth factor receptor beta
   04020 Calcium signaling pathway
    K05089  PDGFRB; platelet-derived growth factor receptor beta
   04151 PI3K-Akt signaling pathway
    K05089  PDGFRB; platelet-derived growth factor receptor beta
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05089  PDGFRB; platelet-derived growth factor receptor beta
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    K05089  PDGFRB; platelet-derived growth factor receptor beta
  Cellular commiunity
   04510 Focal adhesion
    K05089  PDGFRB; platelet-derived growth factor receptor beta
   04540 Gap junction
    K05089  PDGFRB; platelet-derived growth factor receptor beta
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K05089  PDGFRB; platelet-derived growth factor receptor beta
   05230 Central carbon metabolism in cancer
    K05089  PDGFRB; platelet-derived growth factor receptor beta
   05231 Choline metabolism in cancer
    K05089  PDGFRB; platelet-derived growth factor receptor beta
   05206 MicroRNAs in cancer
    K05089  PDGFRB; platelet-derived growth factor receptor beta
   05214 Glioma
    K05089  PDGFRB; platelet-derived growth factor receptor beta
   05218 Melanoma
    K05089  PDGFRB; platelet-derived growth factor receptor beta
   05215 Prostate cancer
    K05089  PDGFRB; platelet-derived growth factor receptor beta
  Infectious diseases
   05166 HTLV-I infection
    K05089  PDGFRB; platelet-derived growth factor receptor beta
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     K05089  PDGFRB; platelet-derived growth factor receptor beta
Protein kinases [BR:ko01001]
 Tyrosine protein kinases
  PDGFR family [OT]
   K05089  PDGFRB; platelet-derived growth factor receptor beta
Enzyme-linked receptors [BR:ko01020]
 Receptor tyrosine kinases
  RTK class III (PDGF receptor family)
   K05089  PDGFRB; platelet-derived growth factor receptor beta
Cytokine receptors [BR:ko04050]
 Receptor tyrosine kinase
  RTK class III (PDGF receptor family)
   K05089  PDGFRB; platelet-derived growth factor receptor beta
Cellular antigens [BR:ko04090]
 Proteins
  K05089  CD140b, PDGFRB; platelet-derived growth factor receptor, beta polypeptide
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
5159(PDGFRB)
PTR: 
462188(PDGFRB)
PPS: 
100975853(PDGFRB)
GGO: 
101150577(PDGFRB)
PON: 
100460001(PDGFRB)
NLE: 
100597894(PDGFRB)
MCC: 
711353(PDGFRB)
MCF: 
CJC: 
100389852(PDGFRB)
MMU: 
18596(Pdgfrb)
RNO: 
24629(Pdgfrb)
CGE: 
100764374(Pdgfrb)
NGI: 
103747076(Pdgfrb)
HGL: 
101721151(Pdgfrb)
OCU: 
100342872(PDGFRB)
TUP: 
102492413(PDGFRB)
CFA: 
442985(PDGFRB)
AML: 
UMR: 
103664600(PDGFRB)
FCA: 
101084600(PDGFRB)
PTG: 
102954207(PDGFRB)
BTA: 
527165(PDGFRB)
BOM: 
102270608(PDGFRB)
PHD: 
102333941(PDGFRB)
CHX: 
102184426(PDGFRB)
OAS: 
101122783(PDGFRB)
SSC: 
100126842(PDGFRB)
CFR: 
102512951(PDGFRB)
BACU: 
103019883(PDGFRB)
LVE: 
103082363(PDGFRB)
ECB: 
100071665(PDGFRB)
MYB: 
102241145(PDGFRB)
MYD: 
102764172(PDGFRB)
PALE: 
102887643(PDGFRB)
MDO: 
100028943(PDGFRB)
SHR: 
100917212(PDGFRB)
OAA: 
100079459(PDGFRB)
GGA: 
770488(PDGFRB)
MGP: 
APLA: 
101799587(PDGFRB)
TGU: 
100223375(PDGFRB)
FAB: 
101809926(PDGFRB)
PHI: 
102111524(PDGFRB)
FPG: 
101918438(PDGFRB)
FCH: 
102052718(PDGFRB)
CLV: 
102096790(PDGFRB)
ASN: 
102372962(PDGFRB)
AMJ: 
102566175(PDGFRB)
PSS: 
102460895(PDGFRB)
CMY: 
102944650(PDGFRB)
ACS: 
100555784(pdgfrb)
PBI: 
103051588(PDGFRB)
XTR: 
100487523(pdgfrb)
DRE: 
559529(pdgfrb)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102361386(PDGFRB)
CMK: 
103188232(pdgfrb)
AQU: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Jones AV, Cross NC
  Title
Oncogenic derivatives of platelet-derived growth factor receptors.
  Journal
Cell Mol Life Sci 61:2912-23 (2004)

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