KEGG   ORTHOLOGY: K05090Help
Entry
K05090                      KO                                     

Name
CSF1R, FMS
Definition
macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
Pathway
Ras signaling pathway
Rap1 signaling pathway
Cytokine-cytokine receptor interaction
Endocytosis
PI3K-Akt signaling pathway
Osteoclast differentiation
Hematopoietic cell lineage
Pathways in cancer
Transcriptional misregulation in cancer
Disease
H00028  
Choriocarcinoma
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K05090  CSF1R, FMS; macrophage colony-stimulating factor 1 receptor
   04015 Rap1 signaling pathway
    K05090  CSF1R, FMS; macrophage colony-stimulating factor 1 receptor
   04151 PI3K-Akt signaling pathway
    K05090  CSF1R, FMS; macrophage colony-stimulating factor 1 receptor
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05090  CSF1R, FMS; macrophage colony-stimulating factor 1 receptor
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    K05090  CSF1R, FMS; macrophage colony-stimulating factor 1 receptor
 Organismal Systems
  Immune system
   04640 Hematopoietic cell lineage
    K05090  CSF1R, FMS; macrophage colony-stimulating factor 1 receptor
  Development
   04380 Osteoclast differentiation
    K05090  CSF1R, FMS; macrophage colony-stimulating factor 1 receptor
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K05090  CSF1R, FMS; macrophage colony-stimulating factor 1 receptor
   05202 Transcriptional misregulation in cancers
    K05090  CSF1R, FMS; macrophage colony-stimulating factor 1 receptor
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     K05090  CSF1R, FMS; macrophage colony-stimulating factor 1 receptor
Protein kinases [BR:ko01001]
 Tyrosine protein kinases
  PDGFR family [OT]
   K05090  CSF1R, FMS; macrophage colony-stimulating factor 1 receptor
Enzyme-linked receptors [BR:ko01020]
 Receptor tyrosine kinases
  RTK class III (PDGF receptor family)
   K05090  CSF1R, FMS; macrophage colony-stimulating factor 1 receptor
Cytokine receptors [BR:ko04050]
 Receptor tyrosine kinase
  RTK class III (PDGF receptor family)
   K05090  CSF1R, FMS; macrophage colony-stimulating factor 1 receptor
Cellular antigens [BR:ko04090]
 Proteins
  K05090  CD115, CSF1R; colony stimulating factor 1 receptor
BRITE hierarchy
Genes
HSA: 
1436(CSF1R)
PTR: 
462187(CSF1R)
PPS: 
100974967(CSF1R)
GGO: 
101151662(CSF1R)
PON: 
100433386(CSF1R)
MCC: 
711512(CSF1R)
MCF: 
102124214(CSF1R)
MMU: 
12978(Csf1r)
RNO: 
307403(Csf1r)
CGE: 
100763221(Csf1r)
HGL: 
101719513(Csf1r)
TUP: 
102491581(CSF1R)
CFA: 
489188(CSF1R)
AML: 
FCA: 
493706(CSF1R)
PTG: 
102953056(CSF1R)
BTA: 
509418(CSF1R)
BOM: 
102272280(CSF1R)
PHD: 
102334299(CSF1R)
CHX: 
SSC: 
100517086(CSF1R)
CFR: 
102513202(CSF1R)
BACU: 
102999126(CSF1R)
LVE: 
103075680(CSF1R)
ECB: 
100060422(CSF1R)
MYB: 
102256301(CSF1R)
MYD: 
102763897(CSF1R)
PALE: 
102886964(CSF1R)
MDO: 
100028926(CSF1R)
SHR: 
100916950(CSF1R)
MGP: 
TGU: 
100220482(CSF1R)
FAB: 
101809748(CSF1R)
PHI: 
102111338(CSF1R)
APLA: 
FPG: 
101918260(CSF1R)
FCH: 
102052893(CSF1R)
CLV: 
102090039(CSF1R)
ASN: 
102373216(CSF1R)
AMJ: 
102565932(CSF1R)
PSS: 
102460494(CSF1R)
CMY: 
102937993(CSF1R)
ACS: 
PBI: 
103051818(CSF1R)
XTR: 
493543(csf1r)
DRE: 
568405(csf1rb) 64274(csf1ra)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Wiesmann C, Muller YA, de Vos AM.
  Title
Ligand-binding sites in Ig-like domains of receptor tyrosine kinases.
  Journal
J Mol Med 78:247-60 (2000)
Reference
PMID:9262961
  Authors
Fixe P, Praloran V
  Title
Macrophage colony-stimulating-factor (M-CSF or CSF-1) and its receptor: structure-function relationships.
  Journal
Eur Cytokine Netw 8:125-36 (1997)

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