KEGG   ORTHOLOGY: K05092Help
Entry
K05092                      KO                                     

Name
FLT3, FLK2
Definition
fms-related tyrosine kinase 3 [EC:2.7.10.1]
Pathway
Cytokine-cytokine receptor interaction
Hematopoietic cell lineage
Pathways in cancer
Transcriptional misregulation in cancer
Acute myeloid leukemia
Central carbon metabolism in cancer
Disease
H00003  
Acute myeloid leukemia (AML)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05092  FLT3, FLK2; fms-related tyrosine kinase 3
 Organismal Systems
  Immune system
   04640 Hematopoietic cell lineage
    K05092  FLT3, FLK2; fms-related tyrosine kinase 3
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K05092  FLT3, FLK2; fms-related tyrosine kinase 3
   05230 Central carbon metabolism in cancer
    K05092  FLT3, FLK2; fms-related tyrosine kinase 3
   05202 Transcriptional misregulation in cancers
    K05092  FLT3, FLK2; fms-related tyrosine kinase 3
   05221 Acute myeloid leukemia
    K05092  FLT3, FLK2; fms-related tyrosine kinase 3
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     K05092  FLT3, FLK2; fms-related tyrosine kinase 3
Protein kinases [BR:ko01001]
 Tyrosine protein kinases
  PDGFR family [OT]
   K05092  FLT3, FLK2; fms-related tyrosine kinase 3
Enzyme-linked receptors [BR:ko01020]
 Receptor tyrosine kinases
  RTK class III (PDGF receptor family)
   K05092  FLT3, FLK2; fms-related tyrosine kinase 3
Cytokine receptors [BR:ko04050]
 Receptor tyrosine kinase
  RTK class III (PDGF receptor family)
   K05092  FLT3, FLK2; fms-related tyrosine kinase 3
Cellular antigens [BR:ko04090]
 Proteins
  K05092  CD135, FLT3; fms-related tyrosine kinase 3
BRITE hierarchy
Genes
HSA: 
2322(FLT3)
PTR: 
452508(FLT3)
PPS: 
100989601(FLT3)
GGO: 
101131781(FLT3)
PON: 
100454731(FLT3)
NLE: 
100589184(FLT3)
MCC: 
721712(FLT3)
MCF: 
102144988(FLT3)
CJC: 
100413316(FLT3)
MMU: 
14255(Flt3)
RNO: 
140635(Flt3)
CGE: 
100761902(Flt3)
NGI: 
103727235(Flt3)
HGL: 
101713724(Flt3)
CFA: 
486025(FLT3)
AML: 
100483963(FLT3)
UMR: 
103664318(FLT3)
FCA: 
101099264(FLT3)
PTG: 
102955843(FLT3)
BTA: 
512700(FLT3)
BOM: 
102272113(FLT3)
PHD: 
102330024(FLT3)
CHX: 
102189319(FLT3)
OAS: 
101112331(FLT3)
SSC: 
100515445(FLT3)
CFR: 
102508422(FLT3)
BACU: 
103008462(FLT3)
LVE: 
103080479(FLT3)
ECB: 
100061780(FLT3)
MYB: 
102244263(FLT3)
MYD: 
102760103(FLT3)
PALE: 
102891572(FLT3)
MDO: 
100025262(FLT3)
SHR: 
100929912(FLT3)
OAA: 
100090467(FLT3)
GGA: 
100858422(FLT3)
MGP: 
100542111(FLT3)
APLA: 
101794861(FLT3)
TGU: 
100219587(FLT3)
FAB: 
101807614(FLT3)
PHI: 
102112465(FLT3)
FPG: 
101924556(FLT3)
FCH: 
102052010(FLT3)
CLV: 
102092160(FLT3)
ASN: 
102372238(FLT3)
AMJ: 
102566323(FLT3)
PSS: 
102460565(FLT3)
CMY: 
102932199(FLT3)
ACS: 
100557093(flt3)
PBI: 
103049084(FLT3)
XTR: 
101733150(flt3)
DRE: 
566708(flt3)
MZE: 
LCM: 
102346199(FLT3)
CMK: 
103183285(flt3)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Meshinchi S, Appelbaum FR
  Title
Structural and functional alterations of FLT3 in acute myeloid leukemia.
  Journal
Clin Cancer Res 15:4263-9 (2009)

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