KEGG   ORTHOLOGY: K05092Help
Entry
K05092                      KO                                     

Name
FLT3, FLK2
Definition
fms-related tyrosine kinase 3 [EC:2.7.10.1]
Pathway
Cytokine-cytokine receptor interaction
Hematopoietic cell lineage
Pathways in cancer
Transcriptional misregulation in cancer
Acute myeloid leukemia
Disease
H00003  
Acute myeloid leukemia (AML)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05092  FLT3, FLK2; fms-related tyrosine kinase 3
 Organismal Systems
  Immune system
   04640 Hematopoietic cell lineage
    K05092  FLT3, FLK2; fms-related tyrosine kinase 3
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K05092  FLT3, FLK2; fms-related tyrosine kinase 3
   05202 Transcriptional misregulation in cancers
    K05092  FLT3, FLK2; fms-related tyrosine kinase 3
   05221 Acute myeloid leukemia
    K05092  FLT3, FLK2; fms-related tyrosine kinase 3
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     K05092  FLT3, FLK2; fms-related tyrosine kinase 3
Protein kinases [BR:ko01001]
 Tyrosine protein kinases
  PDGFR family [Table]
   K05092  FLT3, FLK2; fms-related tyrosine kinase 3
Enzyme-linked receptors [BR:ko01020]
 Receptor tyrosine kinases
  RTK class III (PDGF receptor family)
   K05092  FLT3, FLK2; fms-related tyrosine kinase 3
Cytokine receptors [BR:ko04050]
 Receptor tyrosine kinase
  RTK class III (PDGF receptor family)
   K05092  FLT3, FLK2; fms-related tyrosine kinase 3
Cellular antigens [BR:ko04090]
 Proteins
  K05092  CD135, FLT3; fms-related tyrosine kinase 3
BRITE hierarchy
Genes
HSA: 
2322(FLT3)
PTR: 
452508(FLT3)
PPS: 
100989601(FLT3)
GGO: 
101131781(FLT3)
PON: 
100454731(FLT3)
MCC: 
721712(FLT3)
MCF: 
102144988(FLT3)
MMU: 
14255(Flt3)
RNO: 
140635(Flt3)
CGE: 
100761902(Flt3)
HGL: 
101713724(Flt3)
CFA: 
486025(FLT3)
AML: 
100483963(FLT3)
FCA: 
101099264(FLT3)
PTG: 
102955843(FLT3)
BTA: 
512700(FLT3)
BOM: 
102272113(FLT3)
PHD: 
102330024(FLT3)
CHX: 
102189319(FLT3)
SSC: 
100515445(FLT3)
CFR: 
102508422(FLT3)
ECB: 
100061780(FLT3)
MYB: 
102244263(FLT3)
MYD: 
102760103(FLT3)
PALE: 
102891572(FLT3)
MDO: 
100025262(FLT3)
SHR: 
100929912(FLT3)
OAA: 
100090467(FLT3)
GGA: 
100858422(FLT3)
MGP: 
100542111(FLT3)
TGU: 
100219587(FLT3)
FAB: 
101807614(FLT3)
PHI: 
102112465(FLT3)
APLA: 
101794861(FLT3)
FPG: 
101924556(FLT3)
FCH: 
102052010(FLT3)
CLV: 
102092160(FLT3)
ASN: 
102372238(FLT3)
PSS: 
102460565(FLT3)
CMY: 
102932199(FLT3)
ACS: 
XTR: 
101733150(flt3)
DRE: 
566708(flt3)
MZE: 
LCM: 
102346199(FLT3)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Meshinchi S, Appelbaum FR
  Title
Structural and functional alterations of FLT3 in acute myeloid leukemia.
  Journal
Clin Cancer Res 15:4263-9 (2009)

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