KEGG   ORTHOLOGY: K05093Help
Entry
K05093                      KO                                     

Name
FGFR2
Definition
fibroblast growth factor receptor 2 [EC:2.7.10.1]
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Endocytosis
PI3K-Akt signaling pathway
Signaling pathways regulating pluripotency of stem cells
Regulation of actin cytoskeleton
Pathways in cancer
Prostate cancer
Central carbon metabolism in cancer
Disease
H00018  
Gastric cancer
H00458  
Craniosynostosis
H00642  
Lacrimo-auriculo-dento-digital syndrome (LADD)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K05093  FGFR2; fibroblast growth factor receptor 2
   04015 Rap1 signaling pathway
    K05093  FGFR2; fibroblast growth factor receptor 2
   04010 MAPK signaling pathway
    K05093  FGFR2; fibroblast growth factor receptor 2
   04151 PI3K-Akt signaling pathway
    K05093  FGFR2; fibroblast growth factor receptor 2
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    K05093  FGFR2; fibroblast growth factor receptor 2
  Cell motility
   04810 Regulation of actin cytoskeleton
    K05093  FGFR2; fibroblast growth factor receptor 2
  Cellular commiunity
   04550 Signaling pathways regulating pluripotency of stem cells
    K05093  FGFR2; fibroblast growth factor receptor 2
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K05093  FGFR2; fibroblast growth factor receptor 2
   05230 Central carbon metabolism in cancer
    K05093  FGFR2; fibroblast growth factor receptor 2
   05215 Prostate cancer
    K05093  FGFR2; fibroblast growth factor receptor 2
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     K05093  FGFR2; fibroblast growth factor receptor 2
Protein kinases [BR:ko01001]
 Tyrosine protein kinases
  FGFR family [OT]
   K05093  FGFR2; fibroblast growth factor receptor 2
Enzyme-linked receptors [BR:ko01020]
 Receptor tyrosine kinases
  RTK class IV (FGF receptor family)
   K05093  FGFR2; fibroblast growth factor receptor 2
Cytokine receptors [BR:ko04050]
 Receptor tyrosine kinase
  RTK class IV (FGF receptor family)
   K05093  FGFR2; fibroblast growth factor receptor 2
Cellular antigens [BR:ko04090]
 Proteins
  K05093  CD332, FGFR2; fibroblast growth factor receptor 2
Heparan sulfate/heparin binding proteins [BR:ko00536]
 Growth factors/receptors
  K05093  FGFR2; fibroblast growth factor receptor 2
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
2263(FGFR2)
PTR: 
466220(FGFR2)
PPS: 
100981139(FGFR2)
GGO: 
101153046(FGFR2)
PON: 
100171540(FGFR2)
NLE: 
100598157(FGFR2)
MCC: 
715949(FGFR2)
MCF: 
102143086(FGFR2)
CJC: 
100393573(FGFR2)
MMU: 
14183(Fgfr2)
RNO: 
25022(Fgfr2)
CGE: 
100763455(Fgfr2)
NGI: 
103729272(Fgfr2)
HGL: 
101709077(Fgfr2)
OCU: 
100009417(FGFR2)
TUP: 
102484403(FGFR2)
CFA: 
415125(FGFR2)
AML: 
100468267(FGFR2)
UMR: 
103657802(FGFR2)
FCA: 
101095198(FGFR2)
PTG: 
102964142(FGFR2)
BTA: 
404193(FGFR2)
BOM: 
102270743(FGFR2)
PHD: 
102330293(FGFR2)
CHX: 
102170938(FGFR2)
OAS: 
443548(FGFR2)
SSC: 
396762(FGFR2)
CFR: 
102516073(FGFR2)
BACU: 
103012184(FGFR2)
LVE: 
103090812(FGFR2)
ECB: 
100033956(FGFR2)
MYB: 
102254053(FGFR2)
MYD: 
102763283(FGFR2)
PALE: 
102882899(FGFR2)
MDO: 
100025727(FGFR2)
SHR: 
100932215(FGFR2)
OAA: 
GGA: 
396259(FGFR2)
MGP: 
APLA: 
101791540(FGFR2)
TGU: 
100223379(FGFR2)
FAB: 
101812169(FGFR2)
PHI: 
102105117(FGFR2)
FPG: 
101913692(FGFR2)
FCH: 
102056102(FGFR2)
CLV: 
102091137(FGFR2)
ASN: 
102382394(FGFR2)
AMJ: 
102571176(FGFR2)
PSS: 
102443772(FGFR2)
CMY: 
102938554(FGFR2)
ACS: 
PBI: 
XLA: 
399325(fgfr2)
XTR: 
100124910(fgfr2)
DRE: 
352940(fgfr2)
TRU: 
MZE: 
OLA: 
100049483(mfr2)
XMA: 
LCM: 
102349925(FGFR2)
CMK: 
BFO: 
DME: 
DER: 
DSE: 
DSI: 
DWI: 
DYA: 
AGA: 
AME: 
413200(htl)
TCA: 
HRO: 
LGI: 
AQU: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Wiesmann C, Muller YA, de Vos AM.
  Title
Ligand-binding sites in Ig-like domains of receptor tyrosine kinases.
  Journal
J Mol Med 78:247-60 (2000)
Reference
  Authors
Eswarakumar VP, Lax I, Schlessinger J
  Title
Cellular signaling by fibroblast growth factor receptors.
  Journal
Cytokine Growth Factor Rev 16:139-49 (2005)

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