KEGG   ORTHOLOGY: K05093Help
Entry
K05093                      KO                                     

Name
FGFR2
Definition
fibroblast growth factor receptor 2 [EC:2.7.10.1]
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Endocytosis
PI3K-Akt signaling pathway
Regulation of actin cytoskeleton
Pathways in cancer
Prostate cancer
Disease
H00018  
Gastric cancer
H00458  
Craniosynostosis
H00642  
Lacrimo-auriculo-dento-digital syndrome (LADD)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K05093  FGFR2; fibroblast growth factor receptor 2
   04015 Rap1 signaling pathway
    K05093  FGFR2; fibroblast growth factor receptor 2
   04010 MAPK signaling pathway
    K05093  FGFR2; fibroblast growth factor receptor 2
   04151 PI3K-Akt signaling pathway
    K05093  FGFR2; fibroblast growth factor receptor 2
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    K05093  FGFR2; fibroblast growth factor receptor 2
  Cell motility
   04810 Regulation of actin cytoskeleton
    K05093  FGFR2; fibroblast growth factor receptor 2
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K05093  FGFR2; fibroblast growth factor receptor 2
   05215 Prostate cancer
    K05093  FGFR2; fibroblast growth factor receptor 2
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     K05093  FGFR2; fibroblast growth factor receptor 2
Protein kinases [BR:ko01001]
 Tyrosine protein kinases
  FGFR family [OT]
   K05093  FGFR2; fibroblast growth factor receptor 2
Enzyme-linked receptors [BR:ko01020]
 Receptor tyrosine kinases
  RTK class IV (FGF receptor family)
   K05093  FGFR2; fibroblast growth factor receptor 2
Cytokine receptors [BR:ko04050]
 Receptor tyrosine kinase
  RTK class IV (FGF receptor family)
   K05093  FGFR2; fibroblast growth factor receptor 2
Cellular antigens [BR:ko04090]
 Proteins
  K05093  CD332, FGFR2; fibroblast growth factor receptor 2
Heparan sulfate/heparin binding proteins [BR:ko00536]
 Growth factors/receptors
  K05093  FGFR2; fibroblast growth factor receptor 2
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
2263(FGFR2)
PTR: 
466220(FGFR2)
PPS: 
100981139(FGFR2)
GGO: 
101153046(FGFR2)
PON: 
100171540(FGFR2)
MCC: 
715949(FGFR2)
MCF: 
102143086(FGFR2)
MMU: 
14183(Fgfr2)
RNO: 
25022(Fgfr2)
CGE: 
100763455(Fgfr2)
HGL: 
101709077(Fgfr2)
TUP: 
102484403(FGFR2)
CFA: 
415125(FGFR2)
AML: 
100468267(FGFR2)
FCA: 
101095198(FGFR2)
PTG: 
102964142(FGFR2)
BTA: 
404193(FGFR2)
BOM: 
102270743(FGFR2)
PHD: 
102330293(FGFR2)
CHX: 
102170938(FGFR2)
OAS: 
443548(FGFR2)
SSC: 
396762(FGFR2)
CFR: 
102516073(FGFR2)
BACU: 
103012184(FGFR2)
LVE: 
103090812(FGFR2)
ECB: 
100033956(FGFR2)
MYB: 
102254053(FGFR2)
MYD: 
102763283(FGFR2)
PALE: 
102882899(FGFR2)
MDO: 
100025727(FGFR2)
SHR: 
100932215(FGFR2)
OAA: 
GGA: 
396259(FGFR2)
MGP: 
TGU: 
100223379(FGFR2)
FAB: 
101812169(FGFR2)
PHI: 
102105117(FGFR2)
APLA: 
101791540(FGFR2)
FPG: 
101913692(FGFR2)
FCH: 
102056102(FGFR2)
CLV: 
102091137(FGFR2)
ASN: 
102382394(FGFR2)
AMJ: 
102571176(FGFR2)
PSS: 
102443772(FGFR2)
CMY: 
102938554(FGFR2)
ACS: 
PBI: 
XLA: 
399325(fgfr2)
XTR: 
100124910(fgfr2)
DRE: 
352940(fgfr2)
TRU: 
MZE: 
OLA: 
100049483(mfr2)
XMA: 
LCM: 
102349925(FGFR2)
CMK: 
103185425(fgfr2)
BFO: 
DME: 
DER: 
DSE: 
DSI: 
DWI: 
DYA: 
AGA: 
AME: 
413200(htl)
TCA: 
AQU: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Wiesmann C, Muller YA, de Vos AM.
  Title
Ligand-binding sites in Ig-like domains of receptor tyrosine kinases.
  Journal
J Mol Med 78:247-60 (2000)
Reference
  Authors
Eswarakumar VP, Lax I, Schlessinger J
  Title
Cellular signaling by fibroblast growth factor receptors.
  Journal
Cytokine Growth Factor Rev 16:139-49 (2005)

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