KEGG   ORTHOLOGY: K05094Help
Entry
K05094                      KO                                     
Name
FGFR3
Definition
fibroblast growth factor receptor 3 [EC:2.7.10.1]
Pathway
MAPK signaling pathway
Endocytosis
PI3K-Akt signaling pathway
Regulation of actin cytoskeleton
Pathways in cancer
Bladder cancer
Disease
H00010  
Multiple myeloma
H00022  
Bladder cancer
H00458  
Craniosynostosis
H00505  
FGFR3-related short limb skeletal dysplasias
H00642  
Lacrimo-auriculo-dento-digital syndrome (LADD)
H00997  
CATSHL syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K05094  FGFR3; fibroblast growth factor receptor 3
   04151 PI3K-Akt signaling pathway
    K05094  FGFR3; fibroblast growth factor receptor 3
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    K05094  FGFR3; fibroblast growth factor receptor 3
  Cell motility
   04810 Regulation of actin cytoskeleton
    K05094  FGFR3; fibroblast growth factor receptor 3
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K05094  FGFR3; fibroblast growth factor receptor 3
   05219 Bladder cancer
    K05094  FGFR3; fibroblast growth factor receptor 3
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     K05094  FGFR3; fibroblast growth factor receptor 3
Protein kinases [BR:ko01001]
 Tyrosine protein kinases
  FGFR family
   K05094  FGFR3; fibroblast growth factor receptor 3
Enzyme-linked receptors [BR:ko01020]
 Receptor tyrosine kinases
  RTK class IV (FGF receptor family)
   K05094  FGFR3; fibroblast growth factor receptor 3
Cytokine receptors [BR:ko04050]
 Receptor tyrosine kinase
  RTK class IV (FGF receptor family)
   K05094  FGFR3; fibroblast growth factor receptor 3
Cellular antigens [BR:ko04090]
 Proteins
  K05094  CD333, FGFR3; fibroblast growth factor receptor 3
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
2261(FGFR3)
PTR: 
461067(FGFR3)
PPS: 
100976551(FGFR3)
GGO: 
101139997(FGFR3)
MCC: 
712829(FGFR3)
MMU: 
14184(Fgfr3)
RNO: 
84489(Fgfr3)
CFA: 
488808(FGFR3)
AML: 
BTA: 
281769(FGFR3)
SSC: 
100514115
ECB: 
100034114(FGFR3)
MDO: 
100023287
SHR: 
100913979(FGFR3)
OAA: 
100084071
GGA: 
396515(FGFR3)
MGP: 
100543461
TGU: 
100218924(FGFR3)
XLA: 
399347(fgfr3) 779370(fgfr3)
XTR: 
100196923(fgfr3)
DRE: 
58129(fgfr3)
TRU: 
101063860
OLA: 
100049424(mfr3)
DME: 
Dmel_CG7223(htl)
PHU: 
Phum_PHUM515380
NVE: 
NEMVE_v1g31143
HMG: 
100214111
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Wiesmann C, Muller YA, de Vos AM.
  Title
Ligand-binding sites in Ig-like domains of receptor tyrosine kinases.
  Journal
J Mol Med 78:247-60 (2000)
Reference
  Authors
Eswarakumar VP, Lax I, Schlessinger J
  Title
Cellular signaling by fibroblast growth factor receptors.
  Journal
Cytokine Growth Factor Rev 16:139-49 (2005)
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