KEGG   ORTHOLOGY: K05096Help
Entry
K05096                      KO                                     

Name
FLT1, VEGFR1
Definition
FMS-like tyrosine kinase 1 [EC:2.7.10.1]
Pathway
Ras signaling pathway
Rap1 signaling pathway
Cytokine-cytokine receptor interaction
HIF-1 signaling pathway
Endocytosis
PI3K-Akt signaling pathway
Focal adhesion
Transcriptional misregulation in cancer
Rheumatoid arthritis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K05096  FLT1, VEGFR1; FMS-like tyrosine kinase 1
   04015 Rap1 signaling pathway
    K05096  FLT1, VEGFR1; FMS-like tyrosine kinase 1
   04066 HIF-1 signaling pathway
    K05096  FLT1, VEGFR1; FMS-like tyrosine kinase 1
   04151 PI3K-Akt signaling pathway
    K05096  FLT1, VEGFR1; FMS-like tyrosine kinase 1
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05096  FLT1, VEGFR1; FMS-like tyrosine kinase 1
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    K05096  FLT1, VEGFR1; FMS-like tyrosine kinase 1
  Cell communication
   04510 Focal adhesion
    K05096  FLT1, VEGFR1; FMS-like tyrosine kinase 1
 Human Diseases
  Cancers
   05202 Transcriptional misregulation in cancers
    K05096  FLT1, VEGFR1; FMS-like tyrosine kinase 1
  Immune diseases
   05323 Rheumatoid arthritis
    K05096  FLT1, VEGFR1; FMS-like tyrosine kinase 1
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     K05096  FLT1, VEGFR1; FMS-like tyrosine kinase 1
Protein kinases [BR:ko01001]
 Tyrosine protein kinases
  VEGFR family [Table]
   K05096  FLT1, VEGFR1; FMS-like tyrosine kinase 1
Enzyme-linked receptors [BR:ko01020]
 Receptor tyrosine kinases
  RTK class V (VEGF receptor family)
   K05096  FLT1, VEGFR1; FMS-like tyrosine kinase 1
Cytokine receptors [BR:ko04050]
 Receptor tyrosine kinase
  RTK class V (VEGF receptor family)
   K05096  FLT1, VEGFR1; FMS-like tyrosine kinase 1
BRITE hierarchy
Genes
HSA: 
2321(FLT1)
PTR: 
452512(FLT1)
PPS: 
100977352(FLT1)
GGO: 
PON: 
100456061(FLT1)
MCC: 
574133(FLT1)
MCF: 
102115442(FLT1)
MMU: 
14254(Flt1)
RNO: 
CGE: 
HGL: 
101711333(Flt1)
TUP: 
102480253(FLT1)
CFA: 
403727(FLT1)
AML: 
100483462(FLT1)
FCA: 
101088292(FLT1)
PTG: 
102955273(FLT1)
BTA: 
503620(FLT1)
BOM: 
102269660(FLT1)
PHD: 
102329661(FLT1)
CHX: 
SSC: 
396763(FLT1)
CFR: 
102508666(FLT1)
ECB: 
100033957(FLT1)
MYB: 
MYD: 
PALE: 
MDO: 
SHR: 
OAA: 
GGA: 
MGP: 
TGU: 
FAB: 
PHI: 
APLA: 
FPG: 
FCH: 
CLV: 
ASN: 
PSS: 
CMY: 
ACS: 
XLA: 
373789(vegf-b) 379546
XTR: 
DRE: 
544667(flt1) 796537(kdrl)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
BFO: 
CIN: 
778954(vegfr)
SPU: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
CQU: 
AME: 
413303(Pvr)
NVI: 
TCA: 
BMOR: 
API: 
PHU: 
ISC: 
CEL: 
CBR: 
BMY: 
LOA: 
TSP: 
HMG: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Wiesmann C, Muller YA, de Vos AM.
  Title
Ligand-binding sites in Ig-like domains of receptor tyrosine kinases.
  Journal
J Mol Med 78:247-60 (2000)
Reference
  Authors
Stuttfeld E, Ballmer-Hofer K
  Title
Structure and function of VEGF receptors.
  Journal
IUBMB Life 61:915-22 (2009)

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