KEGG   ORTHOLOGY: K05098Help
Entry
K05098                      KO                                     

Name
KDR, VEGFR2
Definition
kinase insert domain protein receptor [EC:2.7.10.1]
Pathway
Ras signaling pathway
Rap1 signaling pathway
Cytokine-cytokine receptor interaction
Endocytosis
PI3K-Akt signaling pathway
VEGF signaling pathway
Focal adhesion
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K05098  KDR, VEGFR2; kinase insert domain protein receptor
   04015 Rap1 signaling pathway
    K05098  KDR, VEGFR2; kinase insert domain protein receptor
   04370 VEGF signaling pathway
    K05098  KDR, VEGFR2; kinase insert domain protein receptor
   04151 PI3K-Akt signaling pathway
    K05098  KDR, VEGFR2; kinase insert domain protein receptor
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05098  KDR, VEGFR2; kinase insert domain protein receptor
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    K05098  KDR, VEGFR2; kinase insert domain protein receptor
  Cell communication
   04510 Focal adhesion
    K05098  KDR, VEGFR2; kinase insert domain protein receptor
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    K05098  KDR, VEGFR2; kinase insert domain protein receptor
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     K05098  KDR, VEGFR2; kinase insert domain protein receptor
Protein kinases [BR:ko01001]
 Tyrosine protein kinases
  VEGFR family [Table]
   K05098  KDR, VEGFR2; kinase insert domain protein receptor
Enzyme-linked receptors [BR:ko01020]
 Receptor tyrosine kinases
  RTK class V (VEGF receptor family)
   K05098  KDR, VEGFR2; kinase insert domain protein receptor
Cytokine receptors [BR:ko04050]
 Receptor tyrosine kinase
  RTK class V (VEGF receptor family)
   K05098  KDR, VEGFR2; kinase insert domain protein receptor
Cellular antigens [BR:ko04090]
 Proteins
  K05098  CD309, KDR; kinase insert domain receptor (a type III receptor tyrosine kinase)
BRITE hierarchy
Genes
HSA: 
3791(KDR)
PTR: 
461315(KDR)
PPS: 
GGO: 
PON: 
MCC: 
698293(KDR)
MCF: 
MMU: 
16542(Kdr)
RNO: 
25589(Kdr)
CGE: 
HGL: 
TUP: 
CFA: 
482154(KDR)
AML: 
FCA: 
BTA: 
407170(KDR)
BOM: 
PHD: 
CHX: 
SSC: 
397311(KDR)
CFR: 
ECB: 
MYB: 
MDO: 
SHR: 
OAA: 
GGA: 
395323(KDR)
MGP: 
TGU: 
FAB: 
PHI: 
APLA: 
FPG: 
FCH: 
CLV: 
ASN: 
PSS: 
ACS: 
XTR: 
DRE: 
554230(kdr)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
BFO: 
NVI: 
HMG: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Wiesmann C, Muller YA, de Vos AM.
  Title
Ligand-binding sites in Ig-like domains of receptor tyrosine kinases.
  Journal
J Mol Med 78:247-60 (2000)
Reference
  Authors
Stuttfeld E, Ballmer-Hofer K
  Title
Structure and function of VEGF receptors.
  Journal
IUBMB Life 61:915-22 (2009)

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