KEGG   ORTHOLOGY: K05099Help
Entry
K05099                      KO                                     

Name
MET, HGFR
Definition
proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
Pathway
Ras signaling pathway
Rap1 signaling pathway
Cytokine-cytokine receptor interaction
Endocytosis
PI3K-Akt signaling pathway
Axon guidance
Focal adhesion
Adherens junction
Bacterial invasion of epithelial cells
Epithelial cell signaling in Helicobacter pylori infection
Malaria
Pathways in cancer
Transcriptional misregulation in cancer
Proteoglycans in cancer
MicroRNAs in cancer
Renal cell carcinoma
Melanoma
Disease
H00018  
Gastric cancer
H00021  
Renal cell carcinoma
H00046  
Cholangiocarcinoma
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met
   04015 Rap1 signaling pathway
    K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met
   04151 PI3K-Akt signaling pathway
    K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met
  Cellular commiunity
   04510 Focal adhesion
    K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met
   04520 Adherens junction
    K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met
 Organismal Systems
  Development
   04360 Axon guidance
    K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met
   05202 Transcriptional misregulation in cancers
    K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met
   05206 MicroRNAs in cancer
    K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met
   05205 Proteoglycans in cancer
    K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met
   05218 Melanoma
    K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met
   05211 Renal cell carcinoma
    K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met
  Infectious diseases
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met
   05100 Bacterial invasion of epithelial cells
    K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met
   05144 Malaria
    K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met
Protein kinases [BR:ko01001]
 Tyrosine protein kinases
  Met family
   K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met
Enzyme-linked receptors [BR:ko01020]
 Receptor tyrosine kinases
  RTK class VI (HGF receptor family)
   K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met
Cytokine receptors [BR:ko04050]
 Receptor tyrosine kinase
  RTK class VI (HGF receptor family)
   K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met
BRITE hierarchy
Genes
HSA: 
4233(MET)
PTR: 
463671(MET)
PPS: 
GGO: 
PON: 
NLE: 
MCC: 
704562(MET)
MCF: 
CJC: 
MMU: 
17295(Met)
RNO: 
24553(Met)
CGE: 
HGL: 
TUP: 
CFA: 
403438(MET)
AML: 
UMR: 
FCA: 
493669(MET)
PTG: 
BTA: 
280855(MET)
BOM: 
PHD: 
CHX: 
OAS: 
443076(C-MET)
SSC: 
654328(MET)
CFR: 
BACU: 
LVE: 
ECB: 
MYB: 
MYD: 
PALE: 
MDO: 
SHR: 
OAA: 
GGA: 
396134(MET)
MGP: 
APLA: 
TGU: 
FAB: 
PHI: 
FPG: 
FCH: 
CLV: 
ASN: 
AMJ: 
PSS: 
CMY: 
ACS: 
PBI: 
XLA: 
373551(met)
XTR: 
DRE: 
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
BFO: 
CIN: 
445767(rtkX)
SPU: 
ISC: 
BMY: 
LOA: 
TSP: 
HRO: 
LGI: 
AQU: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Ma PC, Maulik G, Christensen J, Salgia R
  Title
c-Met: structure, functions and potential for therapeutic inhibition.
  Journal
Cancer Metastasis Rev 22:309-25 (2003)

DBGET integrated database retrieval system